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John M. Nicoludis
John M. Nicoludis
Computational Structural Biology, Genentech
在 gene.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Interaction of human telomeric DNA with N- methyl mesoporphyrin IX
JM Nicoludis, SP Barrett, JL Mergny, LA Yatsunyk
Nucleic acids research 40 (12), 5432-5447, 2012
2292012
Optimized End-Stacking Provides Specificity of N-Methyl Mesoporphyrin IX for Human Telomeric G-Quadruplex DNA
JM Nicoludis, ST Miller, PD Jeffrey, SP Barrett, PR Rablen, TJ Lawton, ...
Journal of the American Chemical Society 134 (50), 20446-20456, 2012
2012012
Rudimentary G-quadruplex–based telomere capping in Saccharomyces cerevisiae
JS Smith, Q Chen, LA Yatsunyk, JM Nicoludis, MS Garcia, R Kranaster, ...
Nature structural & molecular biology 18 (4), 478-485, 2011
1612011
Induction of G-quadruplex DNA structure by Zn (II) 5, 10, 15, 20-tetrakis (N-methyl-4-pyridyl) porphyrin
AJ Bhattacharjee, K Ahluwalia, S Taylor, O Jin, JM Nicoludis, R Buscaglia, ...
Biochimie 93 (8), 1297-1309, 2011
1032011
N‐methylmesoporphyrin IX fluorescence as a reporter of strand orientation in guanine quadruplexes
NC Sabharwal, V Savikhin, JR Turek‐Herman, JM Nicoludis, VA Szalai, ...
The FEBS journal 281 (7), 1726-1737, 2014
1012014
Structure and sequence analyses of clustered protocadherins reveal antiparallel interactions that mediate homophilic specificity
JM Nicoludis, SY Lau, CPI Schärfe, DS Marks, WA Weihofen, R Gaudet
Structure 23 (11), 2087-2098, 2015
782015
Antiparallel protocadherin homodimers use distinct affinity-and specificity-mediating regions in cadherin repeats 1-4
JM Nicoludis, BE Vogt, AG Green, CPI Schärfe, DS Marks, R Gaudet
Elife 5, e18449, 2016
592016
Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter
AT Bozzi, CM Zimanyi, JM Nicoludis, BK Lee, CH Zhang, R Gaudet
Elife 8, e41124, 2019
552019
Applications of sequence coevolution in membrane protein biochemistry
JM Nicoludis, R Gaudet
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (4), 895-908, 2017
372017
Investigation of the interactions between Pt(II) and Pd(II) derivatives of 5,10,15,20-tetrakis (N-methyl-4-pyridyl) porphyrin and G-quadruplex DNA
NC Sabharwal, O Mendoza, JM Nicoludis, T Ruan, JL Mergny, ...
JBIC Journal of Biological Inorganic Chemistry 21, 227-239, 2016
322016
Interaction specificity of clustered protocadherins inferred from sequence covariation and structural analysis
JM Nicoludis, AG Green, S Walujkar, EJ May, M Sotomayor, DS Marks, ...
Proceedings of the National Academy of Sciences 116 (36), 17825-17830, 2019
312019
Transient water wires mediate selective proton transport in designed channel proteins
HT Kratochvil, LC Watkins, M Mravic, JL Thomaston, JM Nicoludis, ...
Nature chemistry 15 (7), 1012-1021, 2023
182023
Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8
D Sun, Y Sun, E Janezic, T Zhou, M Johnson, C Azumaya, S Noreng, ...
Nature Communications 14 (1), 7940, 2023
72023
Crystal structure of a three-tetrad, parallel, K+-stabilized human telomeric G-quadruplex at 1.35 Å resolution
EV Chen, JM Nicoludis, BM Powell, KS Li, LA Yatsunyk
Acta Crystallographica Section F: Structural Biology Communications 79 (6), 2023
22023
Transient water wires mediate selective proton conduction in designed channel proteins
HT Kratochvil, LC Watkins, WF DeGrado
bioRxiv, 2022
22022
Scalable approaches for generating, validating and incorporating data from high-throughput functional assays to improve clinical variant classification
SR Padigepati, DA Stafford, CA Tan, MR Silvis, K Jamieson, A Keyser, ...
Human Genetics, 1-10, 2024
2024
P244: Developing Bayesian graphical models to provide continuous, probabilistic variant interpretation
T Manders, Y Kobayashi, J Nicoludis, A Numpally, F Facio, B Johnson, ...
Genetics in Medicine Open 1 (1), 100272, 2023
2023
A Probabilistic Graphical Modeling Approach to Variant Interpretation That Improves VUS Resolution and Increases Actionability of Genetic Testing by Providing Continuous …
R Nussbaum, T Manders, J Nicoludis, A Nampally, K Nykamp, ...
JOURNAL OF MOLECULAR DIAGNOSTICS 24 (10), S19-S20, 2022
2022
Developing large-scale molecular stability engines for clinical variant interpretation
JM Nicoludis, GF Ptacek, J Morin-Leisk, A Colavin, CL Araya
Biophysical Journal 121 (3), 325a, 2022
2022
Roles of Hydrogen-Bonding Networks in Proton Channel Function as Revealed through de novo Designed Proton Channels
HT Kratochvil, JM Nicoludis, WF DeGrado
Biophysical Journal 118 (3), 483a, 2020
2020
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