Formulation optimization of Docetaxel loaded self-emulsifying drug delivery system to enhance bioavailability and anti-tumor activity GR Valicherla, KM Dave, AA Syed, M Riyazuddin, AP Gupta, A Singh, ... Scientific reports 6, 26895, 2016 | 91 | 2016 |
Pancreastatin inhibitor activates AMPK pathway via GRP78 and ameliorates dexamethasone induced fatty liver disease in C57BL/6 mice AP Gupta, P Singh, R Garg, GR Valicherla, M Riyazuddin, AA Syed, ... Biomedicine & Pharmacotherapy 116, 108959, 2019 | 42 | 2019 |
Evaluation of anti-hypertensive activity of Ulmus wallichiana extract and fraction in SHR, DOCA-salt- and L-NAME-induced hypertensive rats AA Syed, S Lahiri, D Mohan, GR Valicherla, AP Gupta, M Riyazuddin, ... Journal of ethnopharmacology 193, 555-565, 2016 | 40 | 2016 |
Discovery of pancreastatin inhibitor PSTi8 for the treatment of insulin resistance and diabetes: studies in rodent models of diabetes mellitus Z Hossain, GR Valicherla, AP Gupta, AA Syed, M Riyazuddin, S Chandra, ... Scientific reports 8 (1), 1-13, 2018 | 34 | 2018 |
Pharmacokinetics and brain targeting of trans-resveratrol loaded mixed micelles in rats following intravenous administration R Katekar, G Thombre, M Riyazuddin, A Husain, H Rani, KS Praveena, ... Pharmaceutical Development and Technology 25 (3), 300-307, 2020 | 25 | 2020 |
Pancreastatin inhibitor PSTi8 attenuates hyperinsulinemia induced obesity and inflammation mediated insulin resistance via MAPK/NOX3-JNK pathway AP Gupta, AA Syed, R Garg, UK Goand, P Singh, M Riyazuddin, ... European journal of pharmacology 864, 172723, 2019 | 21 | 2019 |
Pancreastatin inhibitor, PSTi8 ameliorates metabolic health by modulating AKT/GSK-3β and PKCλ/ζ/SREBP1c pathways in high fat diet induced insulin resistance in peri-/post … GR Valicherla, AP Gupta, Z Hossain, M Riyazuddin, AA Syed, A Husain, ... Peptides 120, 170147, 2019 | 21 | 2019 |
Isoalantolactone derivative promotes glucose utilization in skeletal muscle cells and increases energy expenditure in db/db mice via activating AMPK-dependent signaling D Arha, E Ramakrishna, AP Gupta, AK Rai, A Sharma, I Ahmad, ... Molecular and cellular endocrinology 460, 134-151, 2018 | 21 | 2018 |
Skeletal restoration by phosphodiesterase 5 inhibitors in osteopenic mice: evidence of osteoanabolic and osteoangiogenic effects of the drugs S Pal, M Rashid, SK Singh, K Porwal, P Singh, R Mohamed, JR Gayen, ... Bone, 115305, 2020 | 19 | 2020 |
A nutraceutical composition containing diosmin and hesperidin has osteogenic and anti-resorptive effects and expands the anabolic window of teriparatide S Bhattacharyya, S Pal, R Mohamed, P Singh, S Chattopadhyay, ... Biomedicine & Pharmacotherapy 118, 109207, 2019 | 19 | 2019 |
Leprosy drug clofazimine activates peroxisome proliferator-activated receptor-γ and synergizes with imatinib to inhibit chronic myeloid leukemia cells H Kumar, S Chattopadhyay, N Das, S Shree, D Patel, J Mohapatra, ... Haematologica, haematol. 2018.194910, 2019 | 18 | 2019 |
Discovery of a Novel Small-Molecule Inhibitor that Targets PP2A–β-Catenin Signaling and Restricts Tumor Growth and Metastasis S Maheshwari, SR Avula, A Singh, LR Singh, GR Palnati, RK Arya, ... Molecular cancer therapeutics 16 (9), 1791-1805, 2017 | 18 | 2017 |
Pharmacokinetics and bioavailability assessment of Miltefosine in rats using high performance liquid chromatography tandem mass spectrometry GR Valicherla, P Tripathi, SK Singh, AA Syed, M Riyazuddin, A Husain, ... Journal of Chromatography B 1031, 123-130, 2016 | 18 | 2016 |
Combination of Pancreastatin inhibitor PSTi8 with metformin inhibits Fetuin-A in type 2 diabetic mice P Singh, R Garg, UK Goand, M Riyazuddin, MI Reza, AA Syed, AP Gupta, ... Heliyon 6 (10), e05133, 2020 | 17 | 2020 |
Pancreastatin inhibitor PSTi8 protects the obesity associated skeletal muscle insulin resistance in diet induced streptozotocin-treated diabetic mice AP Gupta, R Garg, P Singh, UK Goand, AA Syed, GR Valicherla, ... European Journal of Pharmacology, 173204, 2020 | 11 | 2020 |
Elucidation of pharmacokinetics of novel DNA ligase I inhibitor, S012-1332 in rats: Integration of in vitro and in vivo findings M Riyazuddin, GR Valicherla, A Husain, MK Hussain, M Shukla, ... Journal of pharmaceutical and biomedical analysis 162, 205-214, 2019 | 11 | 2019 |
LC-ESI-MS/MS assay development and validation of a novel antidiabetic peptide PSTi8 in mice plasma using SPE: An application to pharmacokinetics GR Valicherla, M Riyazuddin, S Shahi, AP Gupta, AA Syed, A Husain, ... Journal of Pharmaceutical and Biomedical Analysis 180, 113074, 2020 | 7 | 2020 |
Simultaneous quantification of five biomarkers in ethanolic extract of Cassia occidentalis Linn. stem using liquid chromatography tandem mass spectrometry: application to its … M Riyazuddin, A Husain, S Verma, R Katekar, R Garg, S Kumar, S Satish, ... RSC Advances 10 (8), 4579-4588, 2020 | 7 | 2020 |
Development and validation of LC-MS/MS method for quantification of novel PP2A–β-catenin signalling inhibitor, S011-2111 in mice plasma: Application to its preclinical … M Riyazuddin, A Husain, GR Valicherla, S Verma, AP Gupta, ... Journal of Chromatography B 1130, 121829, 2019 | 7 | 2019 |
Evaluation of oral pharmacokinetics, in vitro metabolism, blood partitioning and plasma protein binding of novel antidiabetic agent, S009‐0629 in rats GR Valicherla, KS Italiya, CP Gupta, S Mishra, M Riyazuddin, AA Syed, ... Drug Development Research 79 (4), 173-183, 2018 | 3 | 2018 |