Landscape of X chromosome inactivation across human tissues T Tukiainen, AC Villani, A Yen, MA Rivas, JL Marshall, R Satija, M Aguirre, ... Nature 550 (7675), 244-248, 2017 | 886 | 2017 |
Genetics of 35 blood and urine biomarkers in the UK Biobank N Sinnott-Armstrong, Y Tanigawa, D Amar, N Mars, C Benner, M Aguirre, ... Nature Genetics 53 (2), 185-194, 2021 | 534 | 2021 |
Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide DM Ruderfer, CG Walsh, MW Aguirre, Y Tanigawa, JD Ribeiro, ... Molecular psychiatry, 1-9, 2019 | 135 | 2019 |
A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank J Qian, Y Tanigawa, W Du, M Aguirre, C Chang, R Tibshirani, MA Rivas, ... PLoS genetics 16 (10), e1009141, 2020 | 119* | 2020 |
Global Biobank Engine: enabling genotype-phenotype browsing for biobank summary statistics G McInnes, Y Tanigawa, C DeBoever, A Lavertu, J Olivieri, M Aguirre, ... Bioinformatics, 2018 | 100 | 2018 |
Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology Y Tanigawa, J Li, JM Justesen, H Horn, M Aguirre, C DeBoever, C Chang, ... Nature Communications 10 (1), 1-14, 2019 | 66 | 2019 |
Phenome-wide burden of copy-number variation in the UK biobank M Aguirre, MA Rivas, J Priest The American Journal of Human Genetics 105 (2), 373-383, 2019 | 65 | 2019 |
Assessing digital phenotyping to enhance genetic studies of human diseases C DeBoever, Y Tanigawa, M Aguirre, G McInnes, A Lavertu, MA Rivas The American Journal of Human Genetics 106 (5), 611-622, 2020 | 57 | 2020 |
Polygenic risk modeling with latent trait-related genetic components M Aguirre, Y Tanigawa, GR Venkataraman, R Tibshirani, T Hastie, ... European Journal of Human Genetics, 1-11, 2021 | 19 | 2021 |
A phenome-wide association study of 26 mendelian genes reveals phenotypic expressivity of common and rare variants within the general population C Tcheandjieu, M Aguirre, S Gustafsson, P Saha, P Potiny, M Haendel, ... PLoS genetics 16 (11), e1008802, 2020 | 15* | 2020 |
Integration of rare expression outlier-associated variants improves polygenic risk prediction C Smail, NM Ferraro, Q Hui, MG Durrant, M Aguirre, Y Tanigawa, ... The American Journal of Human Genetics 109 (6), 1055-1064, 2022 | 14* | 2022 |
Bayesian model comparison for rare-variant association studies GR Venkataraman, C DeBoever, Y Tanigawa, M Aguirre, AG Ioannidis, ... The American Journal of Human Genetics 108 (12), 2354-2367, 2021 | 9* | 2021 |
Learning epistatic polygenic phenotypes with Boolean interactions M Behr, K Kumbier, A Cordova-Palomera, M Aguirre, O Ronen, C Ye, ... Plos one 19 (4), e0298906, 2024 | 7 | 2024 |
Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes M Yu, M Aguirre, M Jia, K Gjoni, A Cordova-Palomera, C Munger, ... Circulation: Genomic and Precision Medicine, e003968, 2023 | 3 | 2023 |
Genetic Determinants of the Interventricular Septum Are Linked to Ventricular Septal Defects and Hypertrophic Cardiomyopathy M Yu, AR Harper, M Aguirre, M Pittman, C Tcheandjieu, D Amgalan, ... Circulation: Genomic and Precision Medicine, e003708, 2023 | 3 | 2023 |
Transcriptomics and chromatin accessibility in multiple African population samples MK DeGorter, PC Goddard, E Karakoc, S Kundu, SM Yan, D Nachun, ... bioRxiv, 2023 | 1 | 2023 |
Gene regulatory network structure informs the distribution of perturbation effects M Aguirre, JP Spence, G Sella, JK Pritchard bioRxiv, 2024.07. 04.602130, 2024 | | 2024 |
Assessment of Polygenic Trait Risk via Trait Components and Applications Thereof MA Rivas, MW Aguirre US Patent App. 17/005,241, 2021 | | 2021 |
A deep learning classifier for local ancestry inference M Aguirre, J Sokol, G Venkataraman, A Ioannidis arXiv preprint arXiv:2011.02081, 2020 | | 2020 |