Coronavirus RNA proofreading: molecular basis and therapeutic targeting F Robson, KS Khan, TK Le, C Paris, S Demirbag, P Barfuss, P Rocchi, ... Molecular Cell, 2020 | 458 | 2020 |
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity TH Wright, BJ Bower, JM Chalker, GJL Bernardes, R Wiewiora, WL Ng, ... Science 354 (6312), aag1465, 2016 | 275 | 2016 |
In vivo epigenetic CRISPR screen identifies Asf1a as an immunotherapeutic target in Kras-mutant lung adenocarcinoma F Li, Q Huang, TA Luster, H Hu, H Zhang, WL Ng, A Khodadadi-Jamayran, ... Cancer Discovery 10 (2), 270-287, 2020 | 150 | 2020 |
Selective radical trifluoromethylation of native residues in proteins M Imiołek, G Karunanithy, WL Ng, AJ Baldwin, V Gouverneur, BG Davis Journal of the American Chemical Society 140 (5), 1568-1571, 2018 | 116 | 2018 |
Simeprevir potently suppresses SARS-CoV-2 replication and synergizes with remdesivir HS Lo, KPY Hui, HM Lai, X He, KS Khan, S Kaur, J Huang, Z Li, ... ACS Central Science 7 (5), 792-802, 2021 | 86 | 2021 |
Pharmacologically reversible zonation-dependent endothelial cell transcriptomic changes with neurodegenerative disease associations in the aged brain L Zhao, Z Li, JSL Vong, X Chen, HM Lai, LYC Yan, J Huang, SKH Sy, ... Nature Communications 11 (1), 1-15, 2020 | 71 | 2020 |
Famotidine inhibits Toll-like receptor 3-mediated inflammatory signaling in SARS-CoV2 infection R Mukherjee, A Bhattacharya, D Bojkova, AR Mehdipour, D Shin, ... Journal of Biological Chemistry, 100925, 2021 | 54 | 2021 |
Nucleic acid-based technologies targeting coronaviruses TK Le, C Paris, KS Khan, F Robson, WL Ng, P Rocchi Trends in Biochemical Sciences, 2020 | 50 | 2020 |
Chemical probes for visualizing intact animal and human brain tissue HM Lai, WL Ng, SM Gentleman, W Wu Cell chemical biology 24 (6), 659-672, 2017 | 43 | 2017 |
Rationalisation and validation of an acrylamide-free procedure in three-dimensional histological imaging HM Lai, AKL Liu, WL Ng, J DeFelice, WS Lee, H Li, W Li, HM Ng, ... PloS one 11 (6), e0158628, 2016 | 42 | 2016 |
Phase separation in viral infections H Li, C Ernst, M Kolonko-Adamska, B Greb-Markiewicz, J Man, V Parissi, ... Trends in Microbiology, 2022 | 38 | 2022 |
Post-translational site-selective protein backbone α-deuteration SRG Galan, JR Wickens, J Dadova, WL Ng, X Zhang, RA Simion, ... Nature chemical biology 14 (10), 955, 2018 | 32 | 2018 |
Carbocyclization of d-glucose: syntheses of gabosine I and streptol TKM Shing, Y Chen, WL Ng Tetrahedron 67 (33), 6001-6005, 2011 | 24 | 2011 |
Loss of TSC1/TSC2 sensitizes immune checkpoint blockade in non–small cell lung cancer Q Huang, F Li, H Hu, Z Fang, Z Gao, G Xia, WL Ng, ... Science Advances 8 (5), eabi9533, 2022 | 23 | 2022 |
Epigenetic CRISPR screens identify Npm1 as a therapeutic vulnerability in non-small cell lung cancer F Li, WL Ng, TA Luster, H Hu, VO Sviderskiy, CM Dowling, ... Cancer Research, 2020 | 22 | 2020 |
Short and Efficient Syntheses of Gabosine I, Streptol, 7-O-Acetylstreptol, 1-epi-Streptol, Gabosine K, and Carba-α-d-glucose from δ-d-Gluconolactone TKM Shing, Y Chen, WL Ng Synlett 2011 (09), 1318-1320, 2011 | 22 | 2011 |
Residue-Selective Protein C-Formylation via Sequential Difluoroalkylation-Hydrolysis M Imiołek, PG Isenegger, WL Ng, A Khan, V Gouverneur, BG Davis ACS central science 7 (1), 145-155, 2021 | 21 | 2021 |
Design, Syntheses, and SAR Studies of Carbocyclic Analogues of Sergliflozin as Potent Sodium‐Dependent Glucose Cotransporter 2 Inhibitors TKM Shing, WL Ng, JYW Chan, CBS Lau Angewandte Chemie International Edition 52 (32), 8401-8405, 2013 | 21 | 2013 |
Concise and Stereodivergent Synthesis of Carbasugars Reveals Unexpected Structure-Activity Relationship (SAR) of SGLT2 Inhibition WL Ng, HC Li, KM Lau, AKN Chan, C Bik-San Lau, TKM Shing Scientific Reports 7 (1), 5581, 2017 | 19 | 2017 |
Development of Alkylated Hydrazides as Highly Potent and Selective Class I Histone Deacetylase Inhibitors with T cell Modulatory Properties P Sun, J Wang, KS Khan, W Yang, BWL Ng, N Ilment, M Zessin, ... Journal of Medicinal Chemistry, 2022 | 13 | 2022 |