Pharmacological inhibition of histone deacetylases by suberoylanilide hydroxamic acid specifically alters gene expression and reduces ischemic injury in the mouse brain G Faraco, T Pancani, L Formentini, P Mascagni, G Fossati, F Leoni, ... Molecular pharmacology 70 (6), 1876-1884, 2006 | 291 | 2006 |
The mitochondrial ATPase inhibitory factor 1 triggers a ROS-mediated retrograde prosurvival and proliferative response L Formentini, M Sánchez-Aragó, L Sánchez-Cenizo, JM Cuezva Molecular cell 45 (6), 731-742, 2012 | 258 | 2012 |
Up-regulation of the ATPase inhibitory factor 1 (IF1) of the mitochondrial H+-ATP synthase in human tumors mediates the metabolic shift of cancer cells to a Warburg phenotype L Sánchez-Cenizo, L Formentini, M Aldea, AD Ortega, P García-Huerta, ... Journal of Biological Chemistry 285 (33), 25308-25313, 2010 | 244 | 2010 |
Inhibition of nicotinamide phosphoribosyltransferase: cellular bioenergetics reveals a mitochondrial insensitive NAD pool M Pittelli, L Formentini, G Faraco, A Lapucci, E Rapizzi, F Cialdai, ... Journal of Biological Chemistry 285 (44), 34106-34114, 2010 | 227 | 2010 |
Mitochondrial ROS production protects the intestine from inflammation through functional M2 macrophage polarization L Formentini, F Santacatterina, CN de Arenas, K Stamatakis, ... Cell reports 19 (6), 1202-1213, 2017 | 176 | 2017 |
In vivo inhibition of the mitochondrial H+‐ATP synthase in neurons promotes metabolic preconditioning L Formentini, MP Pereira, L Sánchez‐Cenizo, F Santacatterina, JJ Lucas, ... The EMBO journal 33 (7), 762-778, 2014 | 133 | 2014 |
Poly (ADP-ribose) catabolism triggers AMP-dependent mitochondrial energy failure L Formentini, A Macchiarulo, G Cipriani, E Camaioni, E Rapizzi, ... Journal of Biological Chemistry 284 (26), 17668-17676, 2009 | 113 | 2009 |
Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo L Formentini, F Moroni, A Chiarugi Biochemical pharmacology 77 (10), 1612-1620, 2009 | 96 | 2009 |
Expression, regulation and clinical relevance of the ATPase inhibitory factor 1 in human cancers M Sánchez-Aragó, L Formentini, I Martínez-Reyes, J García-Bermudez, ... Oncogenesis 2 (4), e46-e46, 2013 | 94 | 2013 |
Coordinate β-adrenergic inhibition of mitochondrial activity and angiogenesis arrest tumor growth C Nuevo-Tapioles, F Santacatterina, K Stamatakis, C Núñez de Arenas, ... Nature communications 11 (1), 3606, 2020 | 88 | 2020 |
On the way to selective PARP‐2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives R Pellicciari, E Camaioni, G Costantino, L Formentini, P Sabbatini, ... ChemMedChem: Chemistry Enabling Drug Discovery 3 (6), 914-923, 2008 | 86 | 2008 |
Poly (ADP-ribose) accumulation and enhancement of postischemic brain damage in 110-kDa poly (ADP-ribose) glycohydrolase null mice A Cozzi, G Cipriani, S Fossati, G Faraco, L Formentini, W Min, U Cortes, ... Journal of Cerebral Blood Flow & Metabolism 26 (5), 684-695, 2006 | 80 | 2006 |
Mitochondria-Mediated Energy Adaption in Cancer: The H+-ATP Synthase-Geared Switch of Metabolism in Human Tumors M Sánchez-Aragó, L Formentini, JM Cuezva Antioxidants & redox signaling 19 (3), 285-298, 2013 | 77 | 2013 |
Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state F Santacatterina, L Sánchez-Cenizo, L Formentini, MA Mobasher, ... Oncotarget 7 (1), 490, 2016 | 74 | 2016 |
The mitochondrial bioenergetic capacity of carcinomas L Formentini, I Martínez‐Reyes, JM Cuezva IUBMB life 62 (7), 2010 | 66 | 2010 |
Long‐lasting neuroprotection and neurological improvement in stroke models with new, potent and brain permeable inhibitors of poly (ADP‐ribose) polymerase F Moroni, A Cozzi, A Chiarugi, L Formentini, E Camaioni, ... British journal of pharmacology 165 (5), 1487-1500, 2012 | 63 | 2012 |
Mono‐galloyl glucose derivatives are potent poly (ADP‐ribose) glycohydrolase (PARG) inhibitors and partially reduce PARP‐1‐dependent cell death L Formentini, P Arapistas, M Pittelli, M Jacomelli, V Pitozzi, S Menichetti, ... British journal of pharmacology 155 (8), 1235-1249, 2008 | 58 | 2008 |
Selective PARP‐2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post‐ischaemic brain damage F Moroni, L Formentini, E Gerace, E Camaioni, DE Pellegrini‐Giampietro, ... British journal of pharmacology 157 (5), 854-862, 2009 | 53 | 2009 |
Mitochondrial H+-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance L Formentini, AJ Ryan, M Gálvez-Santisteban, L Carter, P Taub, JD Lapek, ... Diabetologia 60, 2052-2065, 2017 | 49 | 2017 |
Dysfunctional oxidative phosphorylation shunts branched‐chain amino acid catabolism onto lipogenesis in skeletal muscle C Sánchez‐González, C Nuevo‐Tapioles, JC Herrero Martin, MP Pereira, ... The EMBO Journal 39 (14), e103812, 2020 | 40 | 2020 |