Methods for discovery and characterization of cell subsets in high dimensional mass cytometry data KE Diggins, PB Ferrell Jr, JM Irish Methods 82, 55-63, 2015 | 145 | 2015 |
Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment S Kordasti, B Costantini, T Seidl, P Perez Abellan, M Martinez Llordella, ... Blood, The Journal of the American Society of Hematology 128 (9), 1193-1205, 2016 | 139 | 2016 |
Characterizing cell subsets using marker enrichment modeling KE Diggins, AR Greenplate, N Leelatian, CE Wogsland, JM Irish Nature methods 14 (3), 275-278, 2017 | 108 | 2017 |
In vivo autofluorescence imaging of tumor heterogeneity in response to treatment AT Shah, KE Diggins, AJ Walsh, JM Irish, MC Skala Neoplasia 17 (12), 862-870, 2015 | 106 | 2015 |
Mass cytometry deep phenotyping of human mononuclear phagocytes and myeloid-derived suppressor cells from human blood and bone marrow M Roussel, PB Ferrell Jr, AR Greenplate, F Lhomme, S Le Gallou, ... Journal of leukocyte biology 102 (2), 437-447, 2017 | 97 | 2017 |
Characterizing phenotypes and signaling networks of single human cells by mass cytometry N Leelatian, KE Diggins, JM Irish Single Cell Protein Analysis: Methods and Protocols, 99-113, 2015 | 58 | 2015 |
Machine learning reveals chronic graft-versus-host disease phenotypes and stratifies survival after stem cell transplant for hematologic malignancies JS Gandelman, MT Byrne, AM Mistry, HG Polikowsky, KE Diggins, ... Haematologica 104 (1), 189, 2019 | 53 | 2019 |
High-dimensional analysis of acute myeloid leukemia reveals phenotypic changes in persistent cells during induction therapy PB Ferrell Jr, KE Diggins, HG Polikowsky, SR Mohan, AC Seegmiller, ... PloS one 11 (4), e0153207, 2016 | 50 | 2016 |
Cutting edge: redox signaling hypersensitivity distinguishes human germinal center B cells HG Polikowsky, CE Wogsland, KE Diggins, K Huse, JM Irish The Journal of Immunology 195 (4), 1364-1367, 2015 | 41 | 2015 |
Exhausted-like CD8+ T cell phenotypes linked to C-peptide preservation in alefacept-treated T1D subjects KE Diggins, E Serti, V Muir, M Rosasco, TT Lu, E Balmas, G Nepom, ... JCI insight 6 (3), 2021 | 38 | 2021 |
Computational immune monitoring reveals abnormal double-negative T cells present across human tumor types AR Greenplate, DD McClanahan, BK Oberholtzer, DB Doxie, CE Roe, ... Cancer Immunology Research 7 (1), 86-99, 2019 | 32 | 2019 |
IRF5 genetic risk variants drive myeloid-specific IRF5 hyperactivation and presymptomatic SLE D Li, B Matta, S Song, V Nelson, K Diggins, KR Simpfendorfer, ... JCI insight 5 (2), 2020 | 31 | 2020 |
Generating quantitative cell identity labels with marker enrichment modeling (MEM) KE Diggins, JS Gandelman, CE Roe, JM Irish Current protocols in cytometry 83 (1), 10.21. 1-10.21. 28, 2018 | 25 | 2018 |
Unsupervised machine learning reveals risk stratifying glioblastoma tumor cells N Leelatian, J Sinnaeve, AM Mistry, SM Barone, AA Brockman, ... Elife 9, e56879, 2020 | 22 | 2020 |
Human Germinal Center B Cells Differ from Naïve and Memory B Cells in CD40 Expression and CD40L‐Induced Signaling Response K Huse, CE Wogsland, HG Polikowsky, KE Diggins, EB Smeland, ... Cytometry Part A 95 (4), 442-449, 2019 | 13 | 2019 |
BRAF and MEK inhibitor therapy eliminates Nestin‐expressing melanoma cells in human tumors DB Doxie, AR Greenplate, JS Gandelman, KE Diggins, CE Roe, ... Pigment cell & melanoma research 31 (6), 708-719, 2018 | 12 | 2018 |
Guidelines for standardizing T‐cell cytometry assays to link biomarkers, mechanisms, and disease outcomes in type 1 diabetes JHM Yang, KA Ward‐Hartstonge, DJ Perry, JL Blanchfield, AL Posgai, ... European journal of immunology 52 (3), 372-388, 2022 | 9 | 2022 |
Frequency and phenotype consequence of APOC3 rare variants in patients with very low triglyceride levels DC Crawford, NA Restrepo, KE Diggins, E Farber-Eger, QS Wells BMC Medical Genomics 11, 11-18, 2018 | 8 | 2018 |
Responders to low-dose ATG induce CD4+ T cell exhaustion in type 1 diabetes LM Jacobsen, K Diggins, L Blanchfield, J McNichols, DJ Perry, J Brant, ... JCI insight 8 (16), 2023 | 6 | 2023 |
Testing population-specific quantitative trait associations for clinical outcome relevance in a biorepository linked to electronic health records: LPA and myocardial infarction … L Dumitrescu, KE Diggins, R Goodloe, DC Crawford Biocomputing 2016: Proceedings of the Pacific Symposium, 96-107, 2016 | 5 | 2016 |