CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity ML Burr, CE Sparbier, YC Chan, JC Williamson, K Woods, PA Beavis, ... Nature 549 (7670), 101-105, 2017 | 751 | 2017 |
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer ML Burr, CE Sparbier, KL Chan, YC Chan, A Kersbergen, EYN Lam, ... Cancer cell 36 (4), 385-401. e8, 2019 | 442 | 2019 |
The roles of DNA, RNA and histone methylation in ageing and cancer EM Michalak, ML Burr, AJ Bannister, MA Dawson Nature reviews Molecular cell biology 20 (10), 573-589, 2019 | 424 | 2019 |
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation O Gilan, I Rioja, K Knezevic, MJ Bell, MM Yeung, NR Harker, EYN Lam, ... Science 368 (6489), 387-394, 2020 | 306 | 2020 |
HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation ML Burr, F Cano, S Svobodova, LH Boyle, JM Boname, PJ Lehner Proceedings of the National Academy of Sciences 108 (5), 2034-2039, 2011 | 153 | 2011 |
Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia CC Bell, KA Fennell, YC Chan, F Rambow, MM Yeung, D Vassiliadis, ... Nature communications 10 (1), 2723, 2019 | 150 | 2019 |
PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population ML Burr, H Naseem, A Hinks, S Eyre, LJ Gibbons, J Bowes, AG Wilson, ... Annals of the rheumatic diseases 69 (4), 666-670, 2010 | 139 | 2010 |
HBO1 is required for the maintenance of leukaemia stem cells L MacPherson, J Anokye, MM Yeung, EYN Lam, YC Chan, CF Weng, ... Nature 577 (7789), 266-270, 2020 | 128 | 2020 |
Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway LH Boyle, C Hermann, JM Boname, KM Porter, PA Patel, ML Burr, ... Proceedings of the National Academy of Sciences 110 (9), 3465-3470, 2013 | 128 | 2013 |
The value of ambulatory blood pressure in older adults: the Dublin outcome study ML Burr, E Dolan, EW O'Brien, ET O'Brien, P McCormack Age and ageing 37 (2), 201-206, 2008 | 88 | 2008 |
MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation ML Burr, DJH van den Boomen, H Bye, R Antrobus, EJ Wiertz, PJ Lehner Proceedings of the National Academy of Sciences 110 (35), 14290-14295, 2013 | 75 | 2013 |
Long-term stability of anti-cyclic citrullinated peptide antibody status in patients with early inflammatory polyarthritis ML Burr, S Viatte, M Bukhari, D Plant, DP Symmons, W Thomson, ... Arthritis research & therapy 14, 1-10, 2012 | 43 | 2012 |
SP142 PD-L1 scoring shows high interobserver and intraobserver agreement in triple-negative breast carcinoma but overall low percentage agreement with other PD-L1 clones SP263 … JMB Pang, B Castles, DJ Byrne, P Button, S Hendry, SR Lakhani, ... The American journal of surgical pathology 45 (8), 1108-1117, 2021 | 31 | 2021 |
Metabolic myopathies: a guide and update for clinicians ML Burr, JC Roos, AJK Östör Current opinion in rheumatology 20 (6), 639-647, 2008 | 31 | 2008 |
Rituximab in rheumatoid arthritis following anti-TNF-associated tuberculosis ML Burr, AP Malaviya, JH Gaston, AJ Carmichael, AJK Östör Rheumatology 47 (5), 738-739, 2008 | 28 | 2008 |
Pharmacologic reduction of mitochondrial iron triggers a noncanonical BAX/BAK-dependent cell death S Garciaz, AA Guirguis, S Müller, FC Brown, YC Chan, A Motazedian, ... Cancer Discovery 12 (3), 774-791, 2022 | 21 | 2022 |
Sterol metabolism regulates neuroserpin polymer degradation in the absence of the unfolded protein response in the dementia FENIB BD Roussel, TM Newton, E Malzer, N Simecek, I Haq, SE Thomas, ... Human Molecular Genetics 22 (22), 4616-4626, 2013 | 20 | 2013 |
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes CE Sparbier, A Gillespie, J Gomez, N Kumari, A Motazedian, KL Chan, ... Nature cell biology 25 (2), 258-272, 2023 | 12 | 2023 |
Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses KL Chan, J Gomez, C Cardinez, N Kumari, CE Sparbier, EYN Lam, ... Cancer cell 40 (10), 1190-1206. e9, 2022 | 11 | 2022 |
Studying ubiquitination of MHC class I molecules ML Burr, JM Boname, PJ Lehner Antigen Processing: Methods and Protocols, 109-125, 2013 | 6 | 2013 |