Divergent evolution of protein conformational dynamics in dihydrofolate reductase G Bhabha, DC Ekiert, M Jennewein, CM Zmasek, LM Tuttle, G Kroon, ... Nat Struct Mol Biol, 2013 | 181 | 2013 |
Gcn4-mediator specificity is mediated by a large and dynamic fuzzy protein-protein complex LM Tuttle, D Pacheco, L Warfield, J Luo, J Ranish, S Hahn, RE Klevit Cell reports 22 (12), 3251-3264, 2018 | 124 | 2018 |
A sequence-specific transcription activator motif and powerful synthetic variants that bind Mediator using a fuzzy protein interface L Warfield, LM Tuttle, D Pacheco, RE Klevit, S Hahn Proceedings of the National Academy of Sciences 111 (34), E3506-E3513, 2014 | 100 | 2014 |
BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1 SR Witus, AL Burrell, DP Farrell, J Kang, M Wang, JM Hansen, A Pravat, ... Nature structural & molecular biology 28 (3), 268-277, 2021 | 67 | 2021 |
Model-driven designs of an oscillating gene network LM Tuttle, H Salis, J Tomshine, YN Kaznessis Biophysical journal 89 (6), 3873-3883, 2005 | 66 | 2005 |
Mediator subunit Med15 dictates the conserved “fuzzy” binding mechanism of yeast transcription activators Gal4 and Gcn4 LM Tuttle, D Pacheco, L Warfield, DB Wilburn, S Hahn, RE Klevit Nature communications 12 (1), 2220, 2021 | 42 | 2021 |
Side-Chain Conformational Heterogeneity of Intermediates in the Escherichia coli Dihydrofolate Reductase Catalytic Cycle LM Tuttle, HJ Dyson, PE Wright Biochemistry, 2013 | 21 | 2013 |
Identification of endogenous ligands bound to bacterially expressed human and E. coli dihydrofolate reductase by 2D NMR G Bhabha, L Tuttle, MA Martinez-Yamout, PE Wright FEBS letters 585 (22), 3528-3532, 2011 | 17 | 2011 |
Solution structure of sperm lysin yields novel insights into molecular dynamics of rapid protein evolution DB Wilburn, LM Tuttle, RE Klevit, WJ Swanson Proceedings of the National Academy of Sciences 115 (6), 1310-1315, 2018 | 14 | 2018 |
Side Chain Conformational Averaging in Human Dihydrofolate Reductase LM Tuttle, HJ Dyson, PE Wright Biochemistry, 2014 | 12 | 2014 |
Indirect sexual selection drives rapid sperm protein evolution in abalone DB Wilburn, LM Tuttle, RE Klevit, WJ Swanson Elife 8, e52628, 2019 | 9 | 2019 |
BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation SR Witus, LM Tuttle, W Li, A Zelter, M Wang, KE Kermoade, DB Wilburn, ... The EMBO Journal 42 (15), e113565, 2023 | 6 | 2023 |
Gcn4-Mediator specificity is mediated by a large and dynamic fuzzy protein-protein complex. Cell Rep 22: 3251–3264 LM Tuttle, D Pacheco, L Warfield, J Luo, J Ranish, S Hahn, RE Klevit | 6 | 2018 |
INDIRECT SEXUAL SELECTION DRIVES RAPID EVOLUTION OF AN INTRINSICALLY DISORDERED SPERM PROTEIN D Wilburn, L Tuttle, R Klevit, W Swanson PROTEIN SCIENCE 28, 72-73, 2019 | | 2019 |
Indirect Sexual Selection Drives Rapid Sperm Protein Evolution DB Wilburn, LM Tuttle, RE Klevit, WJ Swanson bioRxiv, 682062, 2019 | | 2019 |
NMR studies of side chain conformations and dynamics in Escherichia coli and human DHFR LM Tuttle The Scripps Research Institute, 2012 | | 2012 |
Masters Thesis: Model-driven designs of an oscillating gene network LM Tuttle University of Minnesota, Twin Cities, 2005 | | 2005 |