Role of tau protein in both physiological and pathological conditions J Avila, JJ Lucas, MAR Perez, F Hernandez Physiological reviews, 2004 | 1210 | 2004 |
Decreased nuclear β‐catenin, tau hyperphosphorylation and neurodegeneration in GSK‐3β conditional transgenic mice JJ Lucas, F Hernández, P Gómez‐Ramos, MA Morán, R Hen, J Avila The EMBO journal, 2001 | 1136 | 2001 |
Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418 R Bhat, Y Xue, S Berg, S Hellberg, M Ormö, Y Nilsson, AC Radesäter, ... Journal of Biological Chemistry 278 (46), 45937-45945, 2003 | 615 | 2003 |
GSK-3β, a pivotal kinase in Alzheimer disease M Llorens-Marítin, J Jurado, F Hernández, J Ávila Frontiers in molecular neuroscience 7, 46, 2014 | 553 | 2014 |
Tauopathies F Hernández, J Avila Cellular and Molecular Life Sciences 64, 2219-2233, 2007 | 465 | 2007 |
Spatial learning deficit in transgenic mice that conditionally over‐express GSK‐3β in the brain but do not form tau filaments F Hernández, J Borrell, C Guaza, J Avila, JJ Lucas Journal of neurochemistry 83 (6), 1529-1533, 2002 | 415 | 2002 |
Glycogen synthase kinase‐3 inhibition is integral to long‐term potentiation C Hooper, V Markevich, F Plattner, R Killick, E Schofield, T Engel, ... European journal of Neuroscience 25 (1), 81-86, 2007 | 408 | 2007 |
GSK3 and tau: two convergence points in Alzheimer's disease F Hernandez, JJ Lucas, J Avila Journal of Alzheimer's disease 33 (s1), S141-S144, 2013 | 360 | 2013 |
GSK3: a possible link between beta amyloid peptide and tau protein F Hernández, EG de Barreda, A Fuster-Matanzo, JJ Lucas, J Avila Experimental neurology 223 (2), 322-325, 2010 | 356 | 2010 |
Neuronal induction of the immunoproteasome in Huntington's disease M Díaz-Hernández, F Hernández, E Martín-Aparicio, P Gómez-Ramos, ... Journal of Neuroscience 23 (37), 11653-11661, 2003 | 322 | 2003 |
Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3 T Engel, F Hernández, J Avila, JJ Lucas Journal of Neuroscience 26 (19), 5083-5090, 2006 | 321 | 2006 |
Extracellular tau is toxic to neuronal cells A Gómez-Ramos, M Díaz-Hernández, R Cuadros, F Hernández, J Avila FEBS letters 580 (20), 4842-4850, 2006 | 289 | 2006 |
Chronic lithium administration to FTDP‐17 tau and GSK‐3β overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre‐formed … T Engel, P Goñi‐Oliver, JJ Lucas, J Avila, F Hernández Journal of neurochemistry 99 (6), 1445-1455, 2006 | 278 | 2006 |
Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo AR Cole, F Causeret, G Yadirgi, CJ Hastie, H McLauchlan, EJ McManus, ... Journal of Biological Chemistry 281 (24), 16591-16598, 2006 | 258 | 2006 |
FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and Tau filaments in forebrain F Lim, F Hernández, JJ Lucas, P Gómez-Ramos, MA Morán, J Ávila Molecular and Cellular Neuroscience 18 (6), 702-714, 2001 | 254 | 2001 |
A path toward precision medicine for neuroinflammatory mechanisms in Alzheimer's disease H Hampel, F Caraci, AC Cuello, G Caruso, R Nisticò, M Corbo, F Baldacci, ... Frontiers in immunology 11, 456, 2020 | 244 | 2020 |
Huntington's disease is a four-repeat tauopathy with tau nuclear rods M Fernández-Nogales, JR Cabrera, M Santos-Galindo, JJM Hoozemans, ... Nature medicine 20 (8), 881-885, 2014 | 240 | 2014 |
Direct evidence of internalization of tau by microglia in vitro and in vivo M Bolós, M Llorens-Martín, J Jurado-Arjona, F Hernández, A Rábano, ... Journal of Alzheimer's Disease 50 (1), 77-87, 2016 | 225 | 2016 |
Chronic lithium treatment decreases mutant tau protein aggregation in a transgenic mouse model M Pérez, F Hernández, F Lim, J Díaz-Nido, J Avila Journal of Alzheimer's Disease 5 (4), 301-308, 2003 | 214 | 2003 |
Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease E Martın-Aparicio, A Yamamoto, F Hernandez, R Hen, J Avila, JJ Lucas Journal of Neuroscience 21 (22), 8772-8781, 2001 | 206 | 2001 |