Screening binary systems of chelating agents combined with carbon or silica gel adsorbents: the development of a cost-effective method to remove palladium from pharmaceutical … L Wang, L Green, Z Li, J McCabe Dunn, X Bu, CJ Welch, C Li, T Wang, ... Organic Process Research & Development 15 (6), 1371-1376, 2011 | 48 | 2011 |
Total synthesis of darobactin a M Nesic, DB Ryffel, J Maturano, M Shevlin, SR Pollack, DR Gauthier Jr, ... Journal of the American Chemical Society 144 (31), 14026-14030, 2022 | 43 | 2022 |
Development of a palladium-catalyzed α-arylation of cyclopropyl nitriles JM McCabe Dunn, JT Kuethe, RK Orr, M Tudge, LC Campeau Organic letters 16 (24), 6314-6317, 2014 | 38 | 2014 |
A modular synthesis of 2-alkyl-and 2-arylchromans via a three-step sequence RK Orr, LC Campeau, HR Chobanian, JMMC Dunn, B Pio, CW Plummer, ... Synthesis 49 (03), 657-666, 2017 | 26 | 2017 |
The allenic Alder-ene reaction: constitutional group selectivity and its application to the synthesis of ovalicin KM Brummond, JM McCabe Tetrahedron 62 (45), 10541-10554, 2006 | 26 | 2006 |
Development of a novel tricyclic class of potent and selective FIXa inhibitors D Meng, P Andre, TJ Bateman, R Berger, YH Chen, K Desai, S Dewnani, ... Bioorganic & Medicinal Chemistry Letters 25 (22), 5437-5443, 2015 | 25 | 2015 |
Ti-based subunit couplings: a concise, modular synthesis of routiennocin methyl ester J McCabe, AJ Phillips Tetrahedron 69 (27-28), 5710-5714, 2013 | 18 | 2013 |
New reactions and processes for the efficient synthesis of a HCV NS5b prodrug RK Orr, JMMC Dunn, A Nolting, AM Hyde, ER Ashley, J Leone, E Sirota, ... Green Chemistry 20 (11), 2519-2525, 2018 | 14 | 2018 |
The safe use of sodium hydride on scale: the process development of a chloropyrimidine displacement JM McCabe Dunn, A Duran-Capece, B Meehan, J Ulis, T Iwama, G Gloor, ... Organic Process Research & Development 15 (6), 1442-1446, 2011 | 14 | 2011 |
Mechanistic Understanding of a Robust and Scalable Synthesis of Per (6-deoxy-6-halo) cyclodextrins, Versatile Intermediates for Cyclodextrin Modification SL Zultanski, N Kuhl, W Zhong, RD Cohen, M Reibarkh, J Jurica, J Kim, ... Organic Process Research & Development 25 (3), 597-607, 2020 | 12 | 2020 |
The protecting-group free selective 3′-functionalization of nucleosides JMMC Dunn, M Reibarkh, EC Sherer, RK Orr, RT Ruck, B Simmons, ... Chemical Science 8 (4), 2804-2810, 2017 | 12 | 2017 |
Discovery and optimization of 2-pyridinone aminal integrase strand transfer inhibitors for the treatment of HIV JD Schreier, MW Embrey, IT Raheem, G Barbe, LC Campeau, D Dubost, ... Bioorganic & Medicinal Chemistry Letters 27 (9), 2038-2046, 2017 | 9 | 2017 |
Rhodium-catalyzed intramolecular cyclopropanation of α-diazo β-keto nitriles containing an unsaturated substituted cycloalkyl group JL Zhu, YP Wu Synlett 28 (12), 1467-1472, 2017 | 7 | 2017 |
Trimethylaluminum (TMA)-catalyzed reaction of alkynyllithiums with ethylene oxide: increased yields and purity of homopropargylic alcohols KM Brummond, JM McCabe Synlett 2005 (16), 2457-2460, 2005 | 6 | 2005 |
The Rhodium (I)‐Catalyzed Alder‐Ene Reaction KM Brummond, JM McCabe Modern Rhodium‐Catalyzed Organic Reactions, 151-172, 2005 | 6 | 2005 |
Selective formation of functionalized α-quaternary malononitriles toward 5, 5-disubstituted pyrrolopyrimidinones A Whitehead, Y Zhang, J McCabe Dunn, EC Sherer, Y Lam, J Stelmach, ... Organic letters 19 (17), 4448-4451, 2017 | 4 | 2017 |
An Approach to 1, 1-Disubstituted Pyrazolylcyclopropane Building Blocks PS Nosik, OS Artamonov, SV Ryabukhin, OO Grygorenko SynOpen 1 (01), 0084-0090, 2017 | 3 | 2017 |
Rapid End-Game Process Development and First GMP Production of MK-7845: An Experimental Antiviral Treatment for COVID-19 NR Deprez, JME Hughes, SO Badir, S Popov, T Andreani, RS Bade, ... Organic Process Research & Development, 2024 | 1 | 2024 |
Processes for the preparation of sugammadex JMMC Dunn, N Kuhl, WY Chen, Y Cao, DR Gauthier Jr, AM Hyde, ... US Patent 11,634,511, 2023 | | 2023 |
Enabling medicinal chemistry as a process chemist JMC Dunn ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |