Characterization and comparison of ATF and TFF in stirred bioreactors for continuous mammalian cell culture processes DJ Karst, E Serra, TK Villiger, M Soos, M Morbidelli Biochemical Engineering Journal 110, 17-26, 2016 | 145 | 2016 |
Process performance and product quality in an integrated continuous antibody production process DJ Karst, F Steinebach, M Soos, M Morbidelli Biotechnology and bioengineering 114 (2), 298-307, 2017 | 144 | 2017 |
Design and operation of a continuous integrated monoclonal antibody production process F Steinebach, N Ulmer, M Wolf, L Decker, V Schneider, R Wälchli, D Karst, ... Biotechnology Progress 33 (5), 1303-1313, 2017 | 112 | 2017 |
Continuous integrated manufacturing of therapeutic proteins DJ Karst, F Steinebach, M Morbidelli Current opinion in biotechnology 53, 76-84, 2018 | 110 | 2018 |
Model based adaptive control of a continuous capture process for monoclonal antibodies production F Steinebach, M Angarita, DJ Karst, T Müller-Späth, M Morbidelli Journal of Chromatography A 1444, 50-56, 2016 | 96 | 2016 |
Experimental and CFD physical characterization of animal cell bioreactors: from micro-to production scale TK Villiger, B Neunstoecklin, DJ Karst, E Lucas, M Stettler, H Broly, ... Biochemical engineering journal 131, 84-94, 2018 | 86 | 2018 |
Modulation and modeling of monoclonal antibody N‐linked glycosylation in mammalian cell perfusion reactors DJ Karst, E Scibona, E Serra, JM Bielser, J Souquet, M Stettler, H Broly, ... Biotechnology and Bioengineering 114 (9), 1978-1990, 2017 | 80 | 2017 |
Development of a shake tube‐based scale‐down model for perfusion cultures MKF Wolf, V Lorenz, DJ Karst, J Souquet, H Broly, M Morbidelli Biotechnology and bioengineering 115 (11), 2703-2713, 2018 | 48 | 2018 |
Intracellular CHO cell metabolite profiling reveals steady‐state dependent metabolic fingerprints in perfusion culture DJ Karst, RF Steinhoff, MRG Kopp, E Serra, M Soos, R Zenobi, ... Biotechnology progress 33 (4), 879-890, 2017 | 37 | 2017 |
A two-step procedure for the design of perfusion bioreactors MKF Wolf, A Pechlaner, V Lorenz, DJ Karst, J Souquet, H Broly, ... Biochemical Engineering Journal 151, 107295, 2019 | 23 | 2019 |
Microarray-based MALDI-TOF mass spectrometry enables monitoring of monoclonal antibody production in batch and perfusion cell cultures RF Steinhoff, DJ Karst, F Steinebach, MRG Kopp, GW Schmidt, A Stettler, ... Methods 104, 33-40, 2016 | 20 | 2016 |
Transcriptome and proteome analysis of steady‐state in a perfusion CHO cell culture process V Bertrand, DJ Karst, A Bachmann, K Cantalupo, M Soos, M Morbidelli Biotechnology and bioengineering 116 (8), 1959-1972, 2019 | 19 | 2019 |
Isotope labeling to determine the dynamics of metabolic response in CHO cell perfusion bioreactors using MALDI‐TOF‐MS DJ Karst, RF Steinhoff, MRG Kopp, M Soos, R Zenobi, M Morbidelli Biotechnology progress 33 (6), 1630-1639, 2017 | 10 | 2017 |
Modulation of transmembrane pressure in manufacturing scale tangential flow filtration N‐1 perfusion seed culture DJ Karst, K Ramer, EH Hughes, C Jiang, PJ Jacobs, FG Mitchelson Biotechnology Progress 36 (6), e3040, 2020 | 8 | 2020 |
Monitoring of antibody glycosylation pattern based on microarray MALDI-TOF mass spectrometry J Hajduk, M Wolf, R Steinhoff, D Karst, J Souquet, H Broly, M Morbidelli, ... Journal of biotechnology 302, 77-84, 2019 | 8 | 2019 |
Characterization and comparison of ATF and TFF in stirred bioreactors for the continuous production of therapeutic proteins DJ Karst, E Serra, TK Villiger, M Soos, M Morbidelli Biochemical Engineering Journal 110, 17-26, 2016 | 7 | 2016 |
Integrated continuous processing for the manufacture of monoclonal antibodies D Karst, F Steinenbach, M Morbidelli | 4 | 2015 |
Tuning metabolic efficiency for increased product yield in high titer fed‐batch Chinese hamster ovary cell culture A Helfer, S Gros, D Kolwyck, DJ Karst Biotechnology Progress 39 (3), e3327, 2023 | 3 | 2023 |
Design of integrated continuous processes for high-quality biotherapeutics F Steinebach, D Karst, M Morbidelli Continuous Biomanufacturing-Innovative Technologies and Methods, 457-480, 2017 | 2 | 2017 |
Perfusion cell culture: Challenges and potentials between lab and manufacturing scale DJ Karst | 1 | 2018 |