| Molecular basis of high viscosity in concentrated antibody solutions: Strategies for high concentration drug product development DS Tomar, S Kumar, SK Singh, S Goswami, L Li MAbs 8 (2), 216-228, 2016 | 173 | 2016 |
| Characterization and higher-order structure assessment of an interchain cysteine-based ADC: impact of drug loading and distribution on the mechanism of aggregation J Guo, S Kumar, M Chipley, O Marcq, D Gupta, Z Jin, DS Tomar, ... Bioconjugate chemistry 27 (3), 604-615, 2016 | 78 | 2016 |
| In-silico prediction of concentration-dependent viscosity curves for monoclonal antibody solutions DS Tomar, L Li, MP Broulidakis, NG Luksha, CT Burns, SK Singh, ... MAbs 9 (3), 476-489, 2017 | 75 | 2017 |
| In Silico Prediction of Diffusion Interaction Parameter (kD), a Key Indicator of Antibody Solution Behaviors DS Tomar, SK Singh, L Li, MP Broulidakis, S Kumar Pharmaceutical Research 35, 1-20, 2018 | 40 | 2018 |
| Adsorption of dichloromethane on activated carbon C Borkar, D Tomar, S Gumma Journal of Chemical & Engineering Data 55 (4), 1640-1644, 2010 | 35 | 2010 |
| Importance of hydrophilic hydration and intramolecular interactions in the thermodynamics of helix–coil transition and helix–helix assembly in a deca-alanine peptide DS Tomar, V Weber, BM Pettitt, D Asthagiri The Journal of Physical Chemistry B 120 (1), 69-76, 2016 | 32 | 2016 |
| Intramolecular Interactions Overcome Hydration to Drive the Collapse Transition of Gly15 D Asthagiri, D Karandur, DS Tomar, BM Pettitt The Journal of Physical Chemistry B 121 (34), 8078-8084, 2017 | 31 | 2017 |
| Rational optimization of a monoclonal antibody for simultaneous improvements in its solution properties and biological activity S Kumar, K Roffi, DS Tomar, D Cirelli, N Luksha, D Meyer, J Mitchell, ... Protein Engineering, Design and Selection 31 (7-8), 313-325, 2018 | 29 | 2018 |
| Solvation free energy of the peptide group: its model dependence and implications for the additive-transfer free-energy model of protein stability DS Tomar, D Asthagiri, V Weber Biophysical journal 105 (6), 1482-1490, 2013 | 25 | 2013 |
| Conditional solvation thermodynamics of isoleucine in model peptides and the limitations of the group-transfer model DS Tomar, V Weber, BM Pettitt, D Asthagiri The Journal of Physical Chemistry B 118 (15), 4080-4087, 2014 | 20 | 2014 |
| Hydrophilic interactions dominate the inverse temperature dependence of polypeptide hydration free energies attributed to hydrophobicity DS Tomar, ME Paulaitis, LR Pratt, DN Asthagiri The Journal of Physical Chemistry Letters 11 (22), 9965-9970, 2020 | 14 | 2020 |
| Masked cytokine polypeptides M Karow, DM Lai, DS Tomar, P Johnson, R Rozenfeld, R O'hagan, H Qiu US Patent 11,053,294, 2021 | 11 | 2021 |
| Stress-dependent flexibility of a full-length human monoclonal antibody: Insights from molecular dynamics to support biopharmaceutical development DS Tomar, G Licari, J Bauer, SK Singh, L Li, S Kumar Journal of Pharmaceutical Sciences 111 (3), 628-637, 2022 | 10 | 2022 |
| Solvophobic and solvophilic contributions in the water-to-aqueous guanidinium chloride transfer free energy of model peptides DS Tomar, N Ramesh, D Asthagiri The Journal of Chemical Physics 148 (22), 2018 | 10 | 2018 |
| Potential parameters for helium adsorption in silicalite DS Tomar, M Singla, S Gumma Microporous and mesoporous materials 142 (1), 116-121, 2011 | 10 | 2011 |
| System size dependence of Hydration-Shell occupancy and its implications for assessing the hydrophobic and hydrophilic contributions to hydration D Asthagiri, DS Tomar The Journal of Physical Chemistry B 124 (5), 798-806, 2020 | 9 | 2020 |
| XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies E Patel, NV Malkova, D Crowe, M Pederzoli-Ribeil, D Fantini, M Fanny, ... Molecular Cancer Therapeutics 23 (4), 421-435, 2024 | 1 | 2024 |
| Engineered cleavable carriers and methods of use thereof E Eryilmaz, CU Bialucha, P Johnson, D Tomar US Patent App. 18/352,762, 2024 | | 2024 |
| MASKED IL-12 CYTOKINE AND THEIR DECOMPOSITION PRODUCTS R Rozenfeld, U Eskiocak, H Qiu, P Johnson, KA Jenkins, ... | | 2024 |
| Masked IL-2-Fc fusion polypeptides M Karow, DM Lai, D Tomar, P Johnson, R Rozenfeld, R O'hagan, H Qiu US Patent 11,866,476, 2024 | | 2024 |
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