LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation JP Green, T Swanton, LV Morris, LY El-Sharkawy, J Cook, S Yu, ... Elife 9, e59704, 2020 | 42 | 2020 |
Design, synthesis and evaluation of oxazaborine inhibitors of the NLRP3 inflammasome AG Baldwin, VS Tapia, T Swanton, CS White, JA Beswick, D Brough, ... ChemMedChem 13 (4), 312-320, 2018 | 31 | 2018 |
Is targeting the inflammasome a way forward for neuroscience drug discovery? T Swanton, J Cook, JA Beswick, S Freeman, CB Lawrence, D Brough Slas discovery: Advancing Life Sciences R&D 23 (10), 991-1017, 2018 | 26 | 2018 |
Selective inhibition of the K+ efflux sensitive NLRP3 pathway by Cl− channel modulation T Swanton, JA Beswick, H Hammadi, L Morris, D Williams, S De Cesco, ... Chemical Science 11 (43), 11720-11728, 2020 | 17 | 2020 |
LRRC8A regulates hypotonicity-induced NLRP3 inflammasome activation JP Green, T Swanton, LV Morris, LY El-Sharkawy, J Cook, S Yu, ... BioRxiv, 2020.06. 11.146225, 2020 | 2 | 2020 |
Squaramides enhance NLRP3 inflammasome activation by lowering intracellular potassium PI Seoane, JA Beswick, AG Leach, T Swanton, LV Morris, K Couper, ... Cell death discovery 9 (1), 469, 2023 | | 2023 |
New insights into targeting the NLRP3 inflammasome for inflammatory disease T Swanton PQDT-UK & Ireland, 2021 | | 2021 |
Selective inhibition of the K T Swanton, JA Beswick, H Hammadi, L Morris, D Williams, S de Cesco, ... | | 2020 |