Stem cell factor receptor/c-Kit: from basic science to clinical implications J Lennartsson, L Rönnstrand Physiological reviews 92 (4), 1619-1649, 2012 | 865 | 2012 |
A cis-acting regulatory mutation causes premature hair graying and susceptibility to melanoma in the horse G Rosengren Pielberg, A Golovko, E Sundström, I Curik, J Lennartsson, ... Nature genetics 40 (8), 1004-1009, 2008 | 382 | 2008 |
Normal and oncogenic forms of the receptor tyrosine kinase kit J Lennartsson, T Jelacic, D Linnekin, R Shivakrupa Stem cells 23 (1), 16-43, 2005 | 357 | 2005 |
VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis F Zhang, Z Tang, X Hou, J Lennartsson, Y Li, AW Koch, P Scotney, C Lee, ... Proceedings of the National Academy of Sciences 106 (15), 6152-6157, 2009 | 355 | 2009 |
The PDGF/PDGFR pathway as a drug target N Papadopoulos, J Lennartsson Molecular aspects of medicine 62, 75-88, 2018 | 258 | 2018 |
VEGF-B inhibits apoptosis via VEGFR-1–mediated suppression of the expression of BH3-only protein genes in mice and rats Y Li, F Zhang, N Nagai, Z Tang, S Zhang, P Scotney, J Lennartsson, ... The Journal of clinical investigation 118 (3), 913-923, 2008 | 253 | 2008 |
Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction J Lennartsson, P Blume-Jensen, M Hermanson, E Pontén, M Carlberg, ... Oncogene 18 (40), 5546-5553, 1999 | 237 | 1999 |
Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors X Li, M Tjwa, L Moons, P Fons, A Noel, A Ny, JM Zhou, J Lennartsson, ... The Journal of clinical investigation 115 (1), 118-127, 2005 | 213 | 2005 |
IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells T Strömberg, S Ekman, L Girnita, LY Dimberg, O Larsson, M Axelson, ... Blood 107 (2), 669-678, 2006 | 197 | 2006 |
Structural and functional properties of platelet-derived growth factor and stem cell factor receptors CH Heldin, J Lennartsson Cold Spring Harbor perspectives in biology 5 (8), a009100, 2013 | 182 | 2013 |
Involvement of platelet‐derived growth factor ligands and receptors in tumorigenesis CH Heldin, J Lennartsson, B Westermark Journal of internal medicine 283 (1), 16-44, 2018 | 162 | 2018 |
Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor K Thömmes, J Lennartsson, M CARLBERG, L Rönnstrand Biochemical Journal 341 (1), 211-216, 1999 | 147 | 1999 |
Stem cell factor promotes mast cell survival via inactivation of FOXO3a-mediated transcriptional induction and MEK-regulated phosphorylation of the proapoptotic protein Bim C Möller, J Alfredsson, M Engström, H Wootz, Z Xiang, J Lennartsson, ... Blood 106 (4), 1330-1336, 2005 | 145 | 2005 |
Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3β phosphorylation Z Tang, P Arjunan, C Lee, Y Li, A Kumar, X Hou, B Wang, P Wardega, ... Journal of Experimental Medicine 207 (4), 867-880, 2010 | 141 | 2010 |
The stem cell factor receptor/c-Kit as a drug target in cancer J Lennartsson, L Ronnstrand Current cancer drug targets 6 (1), 65-75, 2006 | 128 | 2006 |
Lack of evidence of stimulatory autoantibodies to platelet‐derived growth factor receptor in patients with systemic sclerosis JF Classen, D Henrohn, F Rorsman, J Lennartsson, BR Lauwerys, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 102 | 2009 |
Src family kinases are involved in the differential signaling from two splice forms of c-Kit O Voytyuk, J Lennartsson, A Mogi, G Caruana, S Courtneidge, ... Journal of Biological Chemistry 278 (11), 9159-9166, 2003 | 101 | 2003 |
PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets X Hou, A Kumar, C Lee, B Wang, P Arjunan, L Dong, A Maminishkis, ... Proceedings of the National Academy of Sciences 107 (27), 12216-12221, 2010 | 96 | 2010 |
Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification M Vanlandewijck, T Lebouvier, M Andaloussi Mäe, K Nahar, ... PloS one 10 (11), e0143407, 2015 | 90 | 2015 |
Negative and positive regulation of MAPK phosphatase 3 controls platelet-derived growth factor-induced Erk activation A Jurek, K Amagasaki, A Gembarska, CH Heldin, J Lennartsson Journal of Biological Chemistry 284 (7), 4626-4634, 2009 | 90 | 2009 |