The protective role of estrogen and estrogen receptors in cardiovascular disease and the controversial use of estrogen therapy A Iorga, CM Cunningham, S Moazeni, G Ruffenach, S Umar, M Eghbali Biology of sex differences 8, 1-16, 2017 | 758 | 2017 |
Downregulation of microRNA-126 contributes to the failing right ventricle in pulmonary arterial hypertension F Potus, G Ruffenach, A Dahou, C Thebault, S Breuils-Bonnet, ... Circulation 132 (10), 932-943, 2015 | 211 | 2015 |
Potassium channel subfamily K member 3 (KCNK3) contributes to the development of pulmonary arterial hypertension F Antigny, A Hautefort, J Meloche, M Belacel-Ouari, B Manoury, ... Circulation 133 (14), 1371-1385, 2016 | 191 | 2016 |
Bromodomain-containing protein 4: the epigenetic origin of pulmonary arterial hypertension J Meloche, F Potus, M Vaillancourt, A Bourgeois, I Johnson, L Deschamps, ... Circulation research 117 (6), 525-535, 2015 | 172 | 2015 |
Autonomic nervous system involvement in pulmonary arterial hypertension M Vaillancourt, P Chia, S Sarji, J Nguyen, N Hoftman, G Ruffenach, ... Respiratory research 18, 1-15, 2017 | 148 | 2017 |
The role of estrogen receptors in cardiovascular disease L Aryan, D Younessi, M Zargari, S Banerjee, J Agopian, S Rahman, ... International journal of molecular sciences 21 (12), 4314, 2020 | 143 | 2020 |
Adaptation and remodelling of the pulmonary circulation in pulmonary hypertension M Vaillancourt, G Ruffenach, J Meloche, S Bonnet Canadian Journal of Cardiology 31 (4), 407-415, 2015 | 124 | 2015 |
Role for runt-related transcription factor 2 in proliferative and calcified vascular lesions in pulmonary arterial hypertension G Ruffenach, S Chabot, VF Tanguay, A Courboulin, O Boucherat, F Potus, ... American journal of respiratory and critical care medicine 194 (10), 1273-1285, 2016 | 106 | 2016 |
Novel biomarkers for pulmonary arterial hypertension A Anwar, G Ruffenach, A Mahajan, M Eghbali, S Umar Respiratory research 17, 1-10, 2016 | 70 | 2016 |
Pulmonary hypertension secondary to pulmonary fibrosis: clinical data, histopathology and molecular insights G Ruffenach, J Hong, M Vaillancourt, L Medzikovic, M Eghbali Respiratory research 21, 1-14, 2020 | 56 | 2020 |
Estrogen rescues heart failure through estrogen receptor Beta activation A Iorga, S Umar, G Ruffenach, L Aryan, J Li, S Sharma, N Motayagheni, ... Biology of sex differences 9, 1-11, 2018 | 51 | 2018 |
Y-Chromosome Gene, Uty, Protects Against Pulmonary Hypertension by Reducing Proinflammatory Chemokines CM Cunningham, M Li, G Ruffenach, M Doshi, L Aryan, J Hong, J Park, ... American journal of respiratory and critical care medicine 206 (2), 186-196, 2022 | 47 | 2022 |
Single-cell study of two rat models of pulmonary arterial hypertension reveals connections to human pathobiology and drug repositioning J Hong, D Arneson, S Umar, G Ruffenach, CM Cunningham, IS Ahn, ... American journal of respiratory and critical care medicine 203 (8), 1006-1022, 2021 | 47 | 2021 |
Role of oxidized lipids in pulmonary arterial hypertension S Sharma, G Ruffenach, S Umar, N Motayagheni, ST Reddy, M Eghbali Pulmonary circulation 6 (3), 261-273, 2016 | 46 | 2016 |
Sex differences underlying preexisting cardiovascular disease and cardiovascular injury in COVID-19 L Medzikovic, CM Cunningham, M Li, M Amjedi, J Hong, G Ruffenach, ... Journal of Molecular and Cellular Cardiology 148, 25-33, 2020 | 37 | 2020 |
Intralipid protects the heart in late pregnancy against ischemia/reperfusion injury via Caveolin2/STAT3/GSK-3β pathway J Li, G Ruffenach, G Kararigas, CM Cunningham, N Motayagheni, ... Journal of molecular and cellular cardiology 102, 108-116, 2017 | 36 | 2017 |
Role of miRNA-1 and miRNA-21 in acute myocardial ischemia-reperfusion injury and their potential as therapeutic strategy E Jayawardena, L Medzikovic, G Ruffenach, M Eghbali International journal of molecular sciences 23 (3), 1512, 2022 | 28 | 2022 |
Oral 15-Hydroxyeicosatetraenoic Acid Induces Pulmonary Hypertension in Mice by Triggering T Cell–Dependent Endothelial Cell Apoptosis G Ruffenach, E O’connor, M Vaillancourt, J Hong, N Cao, S Sarji, ... Hypertension 76 (3), 985-996, 2020 | 23 | 2020 |
Involvement of Low‐Density Lipoprotein Receptor in the Pathogenesis of Pulmonary Hypertension S Umar, G Ruffenach, S Moazeni, M Vaillancourt, J Hong, C Cunningham, ... Journal of the American Heart Association 9 (2), e012063, 2020 | 19 | 2020 |
Histological hallmarks and role of Slug/PIP axis in pulmonary hypertension secondary to pulmonary fibrosis G Ruffenach, S Umar, M Vaillancourt, J Hong, N Cao, S Sarji, S Moazeni, ... EMBO molecular medicine 11 (9), e10061, 2019 | 17 | 2019 |