Targeting the NF-κB pathway in asthma and chronic obstructive pulmonary disease MR Edwards, NW Bartlett, D Clarke, M Birrell, M Belvisi, SL Johnston Pharmacology & therapeutics 121 (1), 1-13, 2009 | 472 | 2009 |
Lung-resident eosinophils represent a distinct regulatory eosinophil subset C Mesnil, S Raulier, G Paulissen, X Xiao, MA Birrell, D Pirottin, T Janss, ... The Journal of clinical investigation 126 (9), 3279-3295, 2016 | 459 | 2016 |
Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking NS Shenker, S Polidoro, K van Veldhoven, C Sacerdote, F Ricceri, ... Human molecular genetics 22 (5), 843-851, 2013 | 439 | 2013 |
Expression profiling in vivo demonstrates rapid changes in lung microRNA levels following lipopolysaccharide-induced inflammation but not in the anti … SA Moschos, AE Williams, MM Perry, MA Birrell, MG Belvisi, MA Lindsay BMC genomics 8, 1-12, 2007 | 368 | 2007 |
TRPA1 agonists evoke coughing in guinea pig and human volunteers MA Birrell, MG Belvisi, M Grace, L Sadofsky, S Faruqi, DJ Hele, SA Maher, ... American journal of respiratory and critical care medicine 180 (11), 1042-1047, 2009 | 327 | 2009 |
Resveratrol, an extract of red wine, inhibits lipopolysaccharide induced airway neutrophilia and inflammatory mediators through an NF‐κB‐independent mechanism MA Birrell, K McCluskie, S Wong, LE Donnelly, PJ Barnes, MG Belvisi The FASEB journal 19 (7), 1-22, 2005 | 237 | 2005 |
Transient receptor potential (TRP) channels in the airway: role in airway disease MS Grace, M Baxter, E Dubuis, MA Birrell, MG Belvisi British journal of pharmacology 171 (10), 2593-2607, 2014 | 207 | 2014 |
Theobromine inhibits sensory nerve activation and cough OS Usmani, MG Belvisi, HJ Patel, N Crispino, MA Birrell, M Korbonits, ... The FASEB journal 19 (2), 1-16, 2005 | 206 | 2005 |
Peroxisome proliferator-activated receptor gamma agonists as therapy for chronic airway inflammation MG Belvisi, DJ Hele, MA Birrell European journal of pharmacology 533 (1-3), 101-109, 2006 | 200 | 2006 |
Iκ-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma MA Birrell, E Hardaker, S Wong, K McCluskie, M Catley, J De Alba, ... American journal of respiratory and critical care medicine 172 (8), 962-971, 2005 | 182 | 2005 |
Transient receptor potential channels mediate the tussive response to prostaglandin E2 and bradykinin M Grace, MA Birrell, E Dubuis, SA Maher, MG Belvisi Thorax 67 (10), 891-900, 2012 | 177 | 2012 |
Phagocytosis‐dependent activation of a TLR9–BTK–calcineurin–NFAT pathway co‐ordinates innate immunity to Aspergillus fumigatus S Herbst, A Shah, M Mazon Moya, V Marzola, B Jensen, A Reed, ... EMBO molecular medicine 7 (3), 240-258, 2015 | 176 | 2015 |
Moving towards a new generation of animal models for asthma and COPD with improved clinical relevance CS Stevenson, MA Birrell Pharmacology & therapeutics 130 (2), 93-105, 2011 | 163 | 2011 |
DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease J Birch, RK Anderson, C Correia-Melo, D Jurk, G Hewitt, FM Marques, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 309 …, 2015 | 162 | 2015 |
Impact of tobacco‐smoke on key signaling pathways in the innate immune response in lung macrophages MA Birrell, S Wong, MC Catley, MG Belvisi Journal of cellular physiology 214 (1), 27-37, 2008 | 159 | 2008 |
Prostaglandin E2 Mediates Cough via the EP3 Receptor: Implications for Future Disease Therapy SA Maher, MA Birrell, MG Belvisi American journal of respiratory and critical care medicine 180 (10), 923-928, 2009 | 152 | 2009 |
PPAR‐γ agonists as therapy for diseases involving airway neutrophilia MA Birrell, HJ Patel, K McCluskie, S Wong, T Leonard, MH Yacoub, ... European respiratory journal 24 (1), 18-23, 2004 | 149 | 2004 |
A role for sensory nerves in the late asthmatic response K Raemdonck, J De Alba, MA Birrell, M Grace, SA Maher, CG Irvin, ... Thorax 67 (1), 19-25, 2012 | 148 | 2012 |
P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke S Eltom, CS Stevenson, J Rastrick, N Dale, K Raemdonck, S Wong, ... PLoS one 6 (9), e24097, 2011 | 147 | 2011 |
XEN-D0501, a novel transient receptor potential vanilloid 1 antagonist, does not reduce cough in patients with refractory cough MG Belvisi, MA Birrell, MA Wortley, SA Maher, I Satia, H Badri, K Holt, ... American journal of respiratory and critical care medicine 196 (10), 1255-1263, 2017 | 138 | 2017 |