Scalable platform for human embryonic stem cell differentiation to cardiomyocytes in suspended microcarrier cultures M Lecina, S Ting, A Choo, S Reuveny, S Oh Tissue Engineering Part C: Methods 16 (6), 1609-1619, 2010 | 152 | 2010 |
On-line monitoring of yeast cell growth by impedance spectroscopy A Soley, M Lecina, X Gámez, JJ Cairo, P Riu, X Rosell, R Bragos, F Godia Journal of biotechnology 118 (4), 398-405, 2005 | 98 | 2005 |
Microcarriers for Stem Cell Culture S Oh, M Lecina, A Choo, S Reuveny, R Zweigert, A Chen US Patent App. 12/497,591, 2010 | 83 | 2010 |
Lactate and glucose concomitant consumption as a self-regulated pH detoxification mechanism in HEK293 cell cultures L Liste-Calleja, M Lecina, J Lopez-Repullo, J Albiol, C Solà, JJ Cairó Applied microbiology and biotechnology 99, 9951-9960, 2015 | 71 | 2015 |
Electrical impedance spectroscopy measurements using a four-electrode configuration improve on-line monitoring of cell concentration in adherent animal cell cultures E Sarró, M Lecina, A Fontova, C Sola, F Godia, JJ Cairó, R Bragos Biosensors and Bioelectronics 31 (1), 257-263, 2012 | 60 | 2012 |
Optimization of HEK-293S cell cultures for the production of adenoviral vectors in bioreactors using on-line OUR measurements J Gálvez, M Lecina, C Solà, JJ Cairó, F Gòdia Journal of biotechnology 157 (1), 214-222, 2012 | 52 | 2012 |
Enhancing heterologous protein expression and secretion in HEK293 cells by means of combination of CMV promoter and IFNα2 signal peptide R Román, J Miret, F Scalia, A Casablancas, M Lecina, JJ Cairó Journal of Biotechnology 239, 57-60, 2016 | 46 | 2016 |
Metabolic flux balance analysis during lactate and glucose concomitant consumption in HEK293 cell cultures I Martínez‐Monge, J Albiol, M Lecina, L Liste‐Calleja, J Miret, C Solà, ... Biotechnology and Bioengineering 116 (2), 388-404, 2019 | 42 | 2019 |
IPTG limitation avoids metabolic burden and acetic acid accumulation in induced fed-batch cultures of Escherichia coli M15 under glucose limiting conditions M Lecina, E Sarró, A Casablancas, F Gòdia, JJ Cairó Biochemical engineering journal 70, 78-83, 2013 | 42 | 2013 |
Distinct regulation of mitogen-activated protein kinase activities is coupled with enhanced cardiac differentiation of human embryonic stem cells H Kempf, M Lecina, S Ting, R Zweigerdt, S Oh Stem cell research 7 (3), 198-209, 2011 | 39 | 2011 |
Application of on-line OUR measurements to detect actions points to improve baculovirus-insect cell cultures in bioreactors M Lecina, A Soley, J Gràcia, E Espunya, B Lázaro, JJ Cairó, F Gòdia Journal of biotechnology 125 (3), 385-394, 2006 | 38 | 2006 |
HEK293 cell culture media study towards bioprocess optimization: Animal derived component free and animal derived component containing platforms L Liste-Calleja, M Lecina, JJ Cairó Journal of bioscience and bioengineering 117 (4), 471-477, 2014 | 36 | 2014 |
New developments in online OUR monitoring and its application to animal cell cultures I Martínez-Monge, R Roman, P Comas, A Fontova, M Lecina, ... Applied microbiology and biotechnology 103, 6903-6917, 2019 | 29 | 2019 |
Comparison of control strategies for fed‐batch culture of hybridoma cells based on on‐line monitoring of oxygen uptake rate, optical cell density and glucose concentration A Casablancas, X Gámez, M Lecina, C Solà, JJ Cairó, F Gòdia Journal of Chemical Technology & Biotechnology 88 (9), 1680-1689, 2013 | 29 | 2013 |
Application of advanced quantification techniques in nanoparticle-based vaccine development with the Sf9 cell baculovirus expression system E Puente-Massaguer, M Lecina, F Gòdia Vaccine 38 (7), 1849-1859, 2020 | 27 | 2020 |
Nanoscale characterization coupled to multi-parametric optimization of Hi5 cell transient gene expression E Puente-Massaguer, M Lecina, F Gòdia Applied microbiology and biotechnology 102, 10495-10510, 2018 | 27 | 2018 |
Strategies for large-scale expansion of clinical-grade human multipotent mesenchymal stromal cells C Garcia-Fernandez, A Lopez-Fernandez, S Borros, M Lecina, J Vives Biochemical engineering journal 159, 107601, 2020 | 26 | 2020 |
Real‐time and on‐line monitoring of morphological cell parameters using electrical impedance spectroscopy measurements E Sarró, M Lecina, A Fontova, F Gòdia, R Bragós, JJ Cairó Journal of Chemical Technology & Biotechnology 91 (6), 1755-1762, 2016 | 24 | 2016 |
Development of a non-viral platform for rapid virus-like particle production in Sf9 cells E Puente-Massaguer, F Gòdia, M Lecina Journal of Biotechnology 322, 43-53, 2020 | 23 | 2020 |
A new strategy for fed-batch process control of HEK293 cell cultures based on alkali buffer addition monitoring: comparison with OUR dynamic method I Martínez-Monge, P Comas, J Triquell, M Lecina, A Casablancas, ... Applied microbiology and biotechnology 102, 10469-10483, 2018 | 23 | 2018 |