The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase TF Franke, SI Yang, TO Chan, K Datta, A Kazlauskas, DK Morrison, ... Cell 81 (5), 727-736, 1995 | 2618 | 1995 |
PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase J Chung, TC Grammar, KP Lemon, A Kazlauskas, J Blenis Nature 370 (6484), 71-75, 1994 | 913 | 1994 |
Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal M Valius, A Kazlauskas Cell 73 (2), 321-334, 1993 | 796 | 1993 |
Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis S Svegliati Baroni, M Santillo, F Bevilacqua, M Luchetti, T Spadoni, ... New England Journal of Medicine 354 (25), 2667-2676, 2006 | 763 | 2006 |
Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins A Kazlauskas, JA Cooper Cell 58 (6), 1121-1133, 1989 | 629 | 1989 |
Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes D Fambrough, K McClure, A Kazlauskas, ES Lander Cell 97 (6), 727-741, 1999 | 586 | 1999 |
c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF R Plattner, L Kadlec, KA DeMali, A Kazlauskas, AM Pendergast Genes & development 13 (18), 2400-2411, 1999 | 544 | 1999 |
Regulation of chemotaxis by the platelet-derived growth factor receptor-β V Kundra, JA Escobedo, A Kazlauskas, HK Kim, SG Rhee, LT Williams, ... Nature 367 (6462), 474-476, 1994 | 542 | 1994 |
PDGF signaling in cells and mice M Tallquist, A Kazlauskas Cytokine & growth factor reviews 15 (4), 205-213, 2004 | 517 | 2004 |
Binding of GAP to activated PDGF receptors A Kazlauskas, C Ellis, T Pawson, JA Cooper Science 247 (4950), 1578-1581, 1990 | 461 | 1990 |
Evidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (Aryl hydrocarbon) receptor A Kazlauskas, L Poellinger, I Pongratz Journal of Biological Chemistry 274 (19), 13519-13524, 1999 | 426 | 1999 |
The B cell antigen receptor complex: association of Ig-α and Ig-β with distinct cytoplasmic effectors MR Clark, KS Campbell, A Kazlauskas, SA Johnson, M Hertz, TA Potter, ... Science 258 (5079), 123-126, 1992 | 397 | 1992 |
Platelet-derived growth factor-induced H2O2 production requires the activation of phosphatidylinositol 3-kinase YS Bae, JY Sung, OS Kim, YJ Kim, KC Hur, A Kazlauskas, SG Rhee Journal of Biological Chemistry 275 (14), 10527-10531, 2000 | 393 | 2000 |
Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo. A Kashishian, A Kazlauskas, JA Cooper The EMBO journal 11 (4), 1373-1382, 1992 | 383 | 1992 |
Disruption of PDGF Receptor Trafficking by Mutation of Its PI-3 Linase Binding Sites M Joly, A Kazlauskas, FS Fay, S Corvera Science 263 (5147), 684-687, 1994 | 379 | 1994 |
Growth-factor-dependent mitogenesis requires two distinct phases of signalling SM Jones, A Kazlauskas Nature cell biology 3 (2), 165-172, 2001 | 320 | 2001 |
EGF or PDGF receptors activate atypical PKClambda through phosphatidylinositol 3‐kinase. K Akimoto, R Takahashi, S Moriya, N Nishioka, J Takayanagi, K Kimura, ... The EMBO journal 15 (4), 788-798, 1996 | 319 | 1996 |
Phosphoinositide 3-kinase regulates phospholipase Cγ-mediated calcium signaling LE Rameh, SG Rhee, K Spokes, A Kazlauskas, LC Cantley, LG Cantley Journal of Biological Chemistry 273 (37), 23750-23757, 1998 | 307 | 1998 |
Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinase. A Kazlauskas, JA Cooper The EMBO journal 9 (10), 3279-3286, 1990 | 305 | 1990 |
The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp. A Kazlauskas, GS Feng, T Pawson, M Valius Proceedings of the National Academy of Sciences 90 (15), 6939-6943, 1993 | 274 | 1993 |