Robust enumeration of cell subsets from tissue expression profiles AM Newman, CL Liu, MR Green, AJ Gentles, W Feng, Y Xu, CD Hoang, ... Nature methods 12 (5), 453-457, 2015 | 9426 | 2015 |
The immune landscape of cancer V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ... Immunity 48 (4), 812-830. e14, 2018 | 4544 | 2018 |
The prognostic landscape of genes and infiltrating immune cells across human cancers AJ Gentles, AM Newman, CL Liu, SV Bratman, W Feng, D Kim, VS Nair, ... Nature medicine 21 (8), 938-945, 2015 | 2861 | 2015 |
Determining cell type abundance and expression from bulk tissues with digital cytometry AM Newman, CB Steen, CL Liu, AJ Gentles, AA Chaudhuri, F Scherer, ... Nature biotechnology 37 (7), 773-782, 2019 | 2764 | 2019 |
Machine learning identifies stemness features associated with oncogenic dedifferentiation TM Malta, A Sokolov, AJ Gentles, T Burzykowski, L Poisson, JN Weinstein, ... Cell 173 (2), 338-354. e15, 2018 | 1635 | 2018 |
The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors SB Willingham, JP Volkmer, AJ Gentles, D Sahoo, P Dalerba, SS Mitra, ... Proceedings of the National Academy of Sciences 109 (17), 6662-6667, 2012 | 1625 | 2012 |
Annotation, submission and screening of repetitive elements in Repbase: RepbaseSubmitter and Censor O Kohany, AJ Gentles, L Hankus, J Jurka BMC bioinformatics 7, 1-7, 2006 | 923 | 2006 |
Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47 MP Chao, S Jaiswal, R Weissman-Tsukamoto, AA Alizadeh, AJ Gentles, ... Science translational medicine 2 (63), 63ra94-63ra94, 2010 | 829 | 2010 |
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences TS Mikkelsen, MJ Wakefield, B Aken, CT Amemiya, JL Chang, S Duke, ... Nature 447 (7141), 167-177, 2007 | 802 | 2007 |
Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia AJ Gentles, SK Plevritis, R Majeti, AA Alizadeh Jama 304 (24), 2706-2715, 2010 | 468 | 2010 |
A simple method for estimating interactions between a treatment and a large number of covariates L Tian, AA Alizadeh, AJ Gentles, R Tibshirani Journal of the American Statistical Association 109 (508), 1517-1532, 2014 | 437 | 2014 |
Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling EW Weber, KR Parker, E Sotillo, RC Lynn, H Anbunathan, J Lattin, ... Science 372 (6537), eaba1786, 2021 | 383 | 2021 |
Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation MR Green, S Kihira, CL Liu, RV Nair, R Salari, AJ Gentles, J Irish, H Stehr, ... Proceedings of the National Academy of Sciences 112 (10), E1116-E1125, 2015 | 369 | 2015 |
Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma MR Green, AJ Gentles, RV Nair, JM Irish, S Kihira, CL Liu, I Kela, ... Blood, The Journal of the American Society of Hematology 121 (9), 1604-1611, 2013 | 367 | 2013 |
Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker M Jan, MP Chao, AC Cha, AA Alizadeh, AJ Gentles, IL Weissman, ... Proceedings of the National Academy of Sciences 108 (12), 5009-5014, 2011 | 321 | 2011 |
Role of KEAP1/NRF2 and TP53 Mutations in Lung Squamous Cell Carcinoma Development and Radiation Resistance Y Jeong, NT Hoang, A Lovejoy, H Stehr, AM Newman, AJ Gentles, ... Cancer discovery 7 (1), 86-101, 2017 | 285 | 2017 |
Amino acid runs in eukaryotic proteomes and disease associations S Karlin, L Brocchieri, A Bergman, J Mrázek, AJ Gentles Proceedings of the National Academy of Sciences 99 (1), 333-338, 2002 | 265 | 2002 |
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities K Han, SE Pierce, A Li, K Spees, GR Anderson, JA Seoane, YH Lo, ... Nature 580 (7801), 136-141, 2020 | 239 | 2020 |
Prediction of survival in diffuse large B-cell lymphoma based on the expression of 2 genes reflecting tumor and microenvironment AA Alizadeh, AJ Gentles, AJ Alencar, CL Liu, HE Kohrt, R Houot, ... Blood, The Journal of the American Society of Hematology 118 (5), 1350-1358, 2011 | 207 | 2011 |
Genome-scale compositional comparisons in eukaryotes AJ Gentles, S Karlin Genome research 11 (4), 540-546, 2001 | 203 | 2001 |