Cloning and functional expression of two families of β-subunits of the large conductance calcium-activated K+ channel VN Uebele, A Lagrutta, T Wade, DJ Figueroa, Y Liu, E McKenna, ... Journal of Biological Chemistry 275 (30), 23211-23218, 2000 | 300 | 2000 |
Essential thalamic contribution to slow waves of natural sleep F David, JT Schmiedt, HL Taylor, G Orban, G Di Giovanni, VN Uebele, ... The Journal of Neuroscience 33 (50), 19599-19610, 2013 | 230 | 2013 |
Selective T-type calcium channel block in thalamic neurons reveals channel redundancy and physiological impact of ITwindow FM Dreyfus, A Tscherter, AC Errington, JJ Renger, HS Shin, VN Uebele, ... The Journal of Neuroscience 30 (1), 99-109, 2010 | 229 | 2010 |
Presynaptic HCN1 channels regulate Cav3. 2 activity and neurotransmission at select cortical synapses Z Huang, R Lujan, I Kadurin, VN Uebele, JJ Renger, AC Dolphin, ... Nature neuroscience 14 (4), 478-486, 2011 | 204 | 2011 |
Characterization of a voltage-gated K+ channel beta subunit expressed in human heart SK England, VN Uebele, H Shear, J Kodali, PB Bennett, MM Tamkun Proceedings of the National Academy of Sciences 92 (14), 6309-6313, 1995 | 192 | 1995 |
Presynaptic Cav3. 2 channels regulate excitatory neurotransmission in nociceptive dorsal horn neurons MO Jacus, VN Uebele, JJ Renger, SM Todorovic The Journal of Neuroscience 32 (27), 9374-9382, 2012 | 188 | 2012 |
High throughput ion-channel pharmacology: planar-array-based voltage clamp L Kiss, PB Bennett, VN Uebele, KS Koblan, SA Kane, B Neagle, ... Assay and drug development technologies 1 (1, Supplement 2), 127-135, 2003 | 170 | 2003 |
A novel K+ channel β-subunit (hKvβ1. 3) is produced via alternative mRNA splicing SK England, VN Uebele, J Kodali, PB Bennett, MM Tamkun Journal of Biological Chemistry 270 (48), 28531-28534, 1995 | 170 | 1995 |
Functional differences in Kv1. 5 currents expressed in mammalian cell lines are due to the presence of endogenous Kvβ2. 1 subunits VN Uebele, SK England, A Chaudhary, MM Tamkun, DJ Snyders Journal of Biological Chemistry 271 (5), 2406-2412, 1996 | 165 | 1996 |
Molecular Analysis of a Binding Site for Quinidine in a Human Cardiac Delayed Rectifier K+ Channel Role of S6 in Antiarrhythmic Drug Binding SW Yeola, TC Rich, VN Uebele, MM Tamkun, DJ Snyders Circulation Research 78 (6), 1105-1114, 1996 | 161 | 1996 |
Design, synthesis, and evaluation of a novel 4-aminomethyl-4-fluoropiperidine as a T-type Ca2+ channel antagonist WD Shipe, JC Barrow, ZQ Yang, CW Lindsley, FV Yang, KAS Schlegel, ... Journal of medicinal chemistry 51 (13), 3692-3695, 2008 | 141 | 2008 |
Calcineurin signaling mediates activity-dependent relocation of the axon initial segment MD Evans, RP Sammons, S Lebron, AS Dumitrescu, TBK Watkins, ... The Journal of Neuroscience 33 (16), 6950-6963, 2013 | 134 | 2013 |
Orexin receptor antagonism prevents transcriptional and behavioral plasticity resulting from stimulant exposure CJ Winrow, KQ Tanis, DR Reiss, AM Rigby, JM Uslaner, VN Uebele, ... Neuropharmacology 58 (1), 185-194, 2010 | 128 | 2010 |
In vitro characterization of T-type calcium channel antagonist TTA-A2 and in vivo effects on arousal in mice RL Kraus, Y Li, Y Gregan, AL Gotter, VN Uebele, SV Fox, SM Doran, ... Journal of Pharmacology and Experimental Therapeutics 335 (2), 409-417, 2010 | 125 | 2010 |
State-dependent properties of a new T-type calcium channel blocker enhance Ca V 3.2 selectivity and support analgesic effects A Francois, N Kerckhove, M Meleine, A Alloui, C Barrere, A Gelot, ... Pain 154 (2), 283-293, 2013 | 124 | 2013 |
Nerve terminal nicotinic acetylcholine receptors initiate quantal GABA release from perisomatic interneurons by activating axonal T-type (Cav3) Ca2+ channels and Ca2+ release … AH Tang, MA Karson, DA Nagode, JM McIntosh, VN Uebele, JJ Renger, ... The Journal of Neuroscience 31 (38), 13546-13561, 2011 | 106 | 2011 |
Discovery of 1, 4-substituted piperidines as potent and selective inhibitors of T-type calcium channels ZQ Yang, JC Barrow, WD Shipe, KAS Schlegel, Y Shu, FV Yang, ... Journal of medicinal chemistry 51 (20), 6471-6477, 2008 | 100 | 2008 |
Antagonism of T-type calcium channels inhibits high-fat diet–induced weight gain in mice VN Uebele, AL Gotter, CE Nuss, RL Kraus, SM Doran, SL Garson, ... The Journal of clinical investigation 119 (6), 1659-1667, 2009 | 99 | 2009 |
Biphasic cholinergic synaptic transmission controls action potential activity in thalamic reticular nucleus neurons YG Sun, JD Pita-Almenar, CS Wu, JJ Renger, VN Uebele, HC Lu, ... The Journal of Neuroscience 33 (5), 2048-2059, 2013 | 92 | 2013 |
T-type calcium channels consolidate tonic action potential output of thalamic neurons to neocortex C Deleuze, F David, S Béhuret, G Sadoc, HS Shin, VN Uebele, JJ Renger, ... The Journal of Neuroscience 32 (35), 12228-12236, 2012 | 85 | 2012 |