| The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs YI Zhu, T Tchkonia, T Pirtskhalava, AC Gower, H Ding, N Giorgadze, ... Aging cell 14 (4), 644-658, 2015 | 2124 | 2015 |
| A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection XM Chen, PL Splinter, SP O'Hara, NF LaRusso Journal of Biological Chemistry 282 (39), 28929-28938, 2007 | 544 | 2007 |
| Physiology of cholangiocytes JH Tabibian, AI Masyuk, TV Masyuk, SP O’Hara, NF LaRusso Comprehensive Physiology 3 (1), 2013 | 321 | 2013 |
| Multiple TLRs are expressed in human cholangiocytes and mediate host epithelial defense responses to Cryptosporidium parvum via activation of NF-κB XM Chen, SP O’Hara, JB Nelson, PL Splinter, AJ Small, PS Tietz, ... The Journal of Immunology 175 (11), 7447-7456, 2005 | 256 | 2005 |
| Cholangiocyte senescence by way of N‐ras activation is a characteristic of primary sclerosing cholangitis JH Tabibian, SP O'Hara, PL Splinter, CE Trussoni, NF LaRusso Hepatology 59 (6), 2263-2275, 2014 | 251 | 2014 |
| MicroRNA-513 regulates B7-H1 translation and is involved in IFN-γ-induced B7-H1 expression in cholangiocytes AY Gong, R Zhou, G Hu, X Li, PL Splinter, SP O'Hara, NF LaRusso, ... The Journal of Immunology 182 (3), 1325-1333, 2009 | 246 | 2009 |
| Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis JH Tabibian, SP O'Hara, CE Trussoni, PS Tietz, PL Splinter, T Mounajjed, ... Hepatology 63 (1), 185-196, 2016 | 235 | 2016 |
| The dynamic biliary epithelia: molecules, pathways, and disease SP O’Hara, JH Tabibian, PL Splinter, NF LaRusso Journal of hepatology 58 (3), 575-582, 2013 | 179 | 2013 |
| Endothelial cell toll‐like receptor 4 regulates fibrosis‐associated angiogenesis in the liver K Jagavelu, C Routray, U Shergill, SP O'Hara, W Faubion, VH Shah Hepatology 52 (2), 590-601, 2010 | 158 | 2010 |
| Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice ME Guicciardi, CE Trussoni, A Krishnan, SF Bronk, MJL Pisarello, ... Journal of hepatology 69 (3), 676-686, 2018 | 157 | 2018 |
| MicroRNA regulation of innate immune responses in epithelial cells R Zhou, SP O'hara, XM Chen Cellular & molecular immunology 8 (5), 371-379, 2011 | 141 | 2011 |
| The cell biology of Cryptosporidium infection SP O’Hara, XM Chen Microbes and infection 13 (8-9), 721-730, 2011 | 139 | 2011 |
| Targeting senescent cholangiocytes and activated fibroblasts with B‐cell lymphoma‐extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2−/−) mice A Moncsek, MS Al‐Suraih, CE Trussoni, SP O'Hara, PL Splinter, C Zuber, ... Hepatology 67 (1), 247-259, 2018 | 133 | 2018 |
| NFκB p50-CCAAT/enhancer-binding protein β (C/EBPβ)-mediated transcriptional repression of microRNA let-7i following microbial infection SP O'Hara, PL Splinter, GB Gajdos, CE Trussoni, ME Fernandez-Zapico, ... Journal of Biological Chemistry 285 (1), 216-225, 2010 | 126 | 2010 |
| MicroRNAs: key modulators of posttranscriptional gene expression SP O'Hara, JL Mott, PL Splinter, GJ Gores, NF LaRusso Gastroenterology 136 (1), 17-25, 2009 | 123 | 2009 |
| Localized glucose and water influx facilitates Cryptosporidium parvum cellular invasion by means of modulation of host-cell membrane protrusion XM Chen, SP O'Hara, BQ Huang, PL Splinter, JB Nelson, NF LaRusso Proceedings of the National Academy of Sciences 102 (18), 6338-6343, 2005 | 116 | 2005 |
| Apical Organelle Discharge by Cryptosporidium parvum Is Temperature, Cytoskeleton, and Intracellular Calcium Dependent and Required for Host Cell Invasion XM Chen, SP O'Hara, BQ Huang, JB Nelson, JJC Lin, G Zhu, HD Ward, ... Infection and Immunity 72 (12), 6806-6816, 2004 | 110 | 2004 |
| The immunobiology of cholangiocytes XM Chen, SP O'hara, NF LaRusso Immunology and cell biology 86 (6), 497-505, 2008 | 103 | 2008 |
| Characterization of cultured cholangiocytes isolated from livers of patients with primary sclerosing cholangitis JH Tabibian, CE Trussoni, SP O'hara, PL Splinter, JK Heimbach, ... Laboratory investigation 94 (10), 1126-1133, 2014 | 100 | 2014 |
| Primary sclerosing cholangitis and the microbiota: current knowledge and perspectives on etiopathogenesis and emerging therapies JH Tabibian, SP O’hara, KD Lindor Scandinavian journal of gastroenterology 49 (8), 901-908, 2014 | 99 | 2014 |
