关注
Alexander Kleger
Alexander Kleger
未知所在单位机构
在 uni-ulm.de 的电子邮件经过验证
标题
引用次数
引用次数
年份
SARS-CoV-2 variants B. 1.351 and P. 1 escape from neutralizing antibodies
M Hoffmann, P Arora, R Groß, A Seidel, BF Hörnich, AS Hahn, N Krüger, ...
Cell 184 (9), 2384-2393. e12, 2021
9682021
SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas
JA Müller, R Groß, C Conzelmann, J Krüger, U Merle, J Steinhart, T Weil, ...
Nature metabolism 3 (2), 149-165, 2021
4932021
Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling
M Hohwieler, A Illing, PC Hermann, T Mayer, M Stockmann, L Perkhofer, ...
Gut 66 (3), 473-486, 2017
2232017
Interpreting type 1 diabetes risk with genetics and single-cell epigenomics
J Chiou, RJ Geusz, ML Okino, JY Han, M Miller, R Melton, E Beebe, ...
Nature 594 (7863), 398-402, 2021
2162021
Telomerase gene mutations are associated with cirrhosis formation
D Hartmann, U Srivastava, M Thaler, KN Kleinhans, G N'kontchou, ...
Hepatology 53 (5), 1608-1617, 2011
1992011
European Guideline on IgG4-related digestive disease–UEG and SGF evidence-based recommendations
JM Löhr, U Beuers, M Vujasinovic, D Alvaro, JB Frøkjær, F Buttgereit, ...
United European gastroenterology journal 8 (6), 637-666, 2020
1632020
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro
C Prelli Bozzo, R Nchioua, M Volcic, L Koepke, J Krüger, D Schütz, ...
Nature communications 12 (1), 4584, 2021
1512021
Loss of ATM accelerates pancreatic cancer formation and epithelial–mesenchymal transition
R Russell, L Perkhofer, S Liebau, Q Lin, A Lechel, FM Feld, E Hessmann, ...
Nature communications 6 (1), 7677, 2015
1492015
DNA damage repair as a target in pancreatic cancer: state-of-the-art and future perspectives
L Perkhofer, J Gout, E Roger, FK de Almeida, CB Simões, L Wiesmüller, ...
Gut 70 (3), 606-617, 2021
1412021
Modulation of calcium-activated potassium channels induces cardiogenesis of pluripotent stem cells and enrichment of pacemaker-like cells
A Kleger, T Seufferlein, D Malan, M Tischendorf, A Storch, A Wolheim, ...
Circulation 122 (18), 1823-1836, 2010
1412010
ATM deficiency generating genomic instability sensitizes pancreatic ductal adenocarcinoma cells to therapy-induced DNA damage
L Perkhofer, A Schmitt, MC Romero Carrasco, M Ihle, S Hampp, ...
Cancer research 77 (20), 5576-5590, 2017
1042017
Smarter drugs emerging in pancreatic cancer therapy
A Kleger, L Perkhofer, T Seufferlein
Annals of Oncology 25 (7), 1260-1270, 2014
982014
Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection
L Wettstein, T Weil, C Conzelmann, JA Müller, R Groß, M Hirschenberger, ...
Nature communications 12 (1), 1726, 2021
972021
The role of pluripotency factors to drive stemness in gastrointestinal cancer
M Müller, PC Hermann, S Liebau, C Weidgang, T Seufferlein, A Kleger, ...
Stem cell research 16 (2), 349-357, 2016
942016
TBX3 directs cell-fate decision toward mesendoderm
CE Weidgang, R Russell, PR Tata, SJ Kühl, A Illing, M Müller, Q Lin, ...
Stem cell reports 1 (3), 248-265, 2013
902013
Mesodermal cell types induce neurogenesis from adult human hippocampal progenitor cells
A Hermann, M Maisel, S Liebau, M Gerlach, A Kleger, J Schwarz, KS Kim, ...
Journal of neurochemistry 98 (2), 629-640, 2006
892006
Protein kinase D2 is a crucial regulator of tumour cell–endothelial cell communication in gastrointestinal tumours
N Azoitei, GV Pusapati, A Kleger, P Möller, R Küfer, F Genze, M Wagner, ...
Gut 59 (10), 1316-1330, 2010
872010
Drug inhibition of SARS-CoV-2 replication in human pluripotent stem cell–derived intestinal organoids
J Krüger, R Groß, C Conzelmann, JA Müller, L Koepke, KMJ Sparrer, ...
Cellular and Molecular Gastroenterology and Hepatology 11 (4), 935-948, 2021
852021
Detection of hot-spot mutations in circulating cell-free DNA from patients with intraductal papillary mucinous neoplasms of the pancreas
AW Berger, D Schwerdel, IG Costa, T Hackert, O Strobel, S Lam, TF Barth, ...
Gastroenterology 151 (2), 267-270, 2016
832016
PDX-derived organoids model in vivo drug response and secrete biomarkers
L Huang, B Bockorny, I Paul, D Akshinthala, PO Frappart, O Gandarilla, ...
JCI insight 5 (21), 2020
822020
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