Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2 D Héja, A Kocsis, J Dobó, K Szilágyi, R Szász, P Závodszky, G Pál, P Gál Proceedings of the National Academy of Sciences 109 (26), 10498-10503, 2012 | 264 | 2012 |
DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond P Rapali, Á Szenes, L Radnai, A Bakos, G Pál, L Nyitray The FEBS journal 278 (17), 2980-2996, 2011 | 165 | 2011 |
Phage display in biotechnology and drug discovery CR Geyer, SS Sidhu CRC Press, 2015 | 159* | 2015 |
Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning G Pál, JLK Kouadio, DR Artis, AA Kossiakoff, SS Sidhu Journal of Biological Chemistry 281 (31), 22378-22385, 2006 | 155 | 2006 |
Two mutations in rat trypsin confer resistance against autolysis É Várallyay, G Pál, A Patthy, L Szilágyi, L Gráf Biochemical and biophysical research communications 243 (1), 56-60, 1998 | 136 | 1998 |
MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked J Dobó, D Szakács, G Oroszlán, E Kortvely, B Kiss, E Boros, R Szász, ... Scientific reports 6 (1), 1-12, 2016 | 132 | 2016 |
Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PLA2R1–associated membranous nephropathy G Haddad, JM Lorenzen, H Ma, N de Haan, H Seeger, C Zaghrini, ... The Journal of clinical investigation 131 (5), 2021 | 113 | 2021 |
Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and-2 are essential for lectin pathway activation and reveal structural … D Héja, V Harmat, K Fodor, M Wilmanns, J Dobó, KA Kékesi, P Závodszky, ... Journal of Biological Chemistry 287 (24), 20290-20300, 2012 | 103 | 2012 |
The emerging roles of mannose‐binding lectin‐associated serine proteases (MASP s) in the lectin pathway of complement and beyond J Dobó, G Pál, L Cervenak, P Gál Immunological reviews 274 (1), 98-111, 2016 | 102 | 2016 |
Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and-2 … A Kocsis, KA Kékesi, R Szász, BM Végh, J Balczer, J Dobó, P Závodszky, ... The Journal of Immunology 185 (7), 4169-4178, 2010 | 90 | 2010 |
Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation … M Megyeri, V Harmat, B Major, Á Végh, J Balczer, D Héja, K Szilágyi, ... Journal of Biological Chemistry 288 (13), 8922-8934, 2013 | 83 | 2013 |
Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome P Rapali, L Radnai, D Süveges, V Harmat, F Tölgyesi, WY Wahlgren, ... PloS one 6 (4), e18818, 2011 | 80 | 2011 |
Human Cationic Trypsinogen Arg117 IS THE REACTIVE SITE OF AN INHIBITORY SURFACE LOOP THAT CONTROLS SPONTANEOUS ZYMOGEN ACTIVATION Z Kukor, M Tóth, G Pál, M Sahin-Tóth Journal of Biological Chemistry 277 (8), 6111-6117, 2002 | 75 | 2002 |
Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization B Bernat, G Pal, M Sun, AA Kossiakoff Proceedings of the National Academy of Sciences 100 (3), 952-957, 2003 | 69 | 2003 |
The functional binding epitope of a high affinity variant of human growth hormone mapped by shotgun alanine-scanning mutagenesis: insights into the mechanisms responsible for … G Pal, AA Kossiakoff, SS Sidhu Journal of molecular biology 332 (1), 195-204, 2003 | 67 | 2003 |
MASP-1 and MASP-2 Do Not Activate Pro–Factor D in Resting Human Blood, whereas MASP-3 Is a Potential Activator: Kinetic Analysis Involving Specific MASP-1 and MASP-2 Inhibitors G Oroszlán, E Kortvely, D Szakács, A Kocsis, S Dammeier, A Zeck, ... The Journal of Immunology 196 (2), 857-865, 2016 | 63 | 2016 |
Proteinase inhibitors from desert locust, Schistocerca gregaria: engineering of both P1 and P1′ residues converts a potent chymotrypsin inhibitor to a potent trypsin inhibitor Z Malik, S Amir, G Pál, Z Buzás, É Várallyay, J Antal, Z Szilágyi, K Vékey, ... Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1999 | 63 | 1999 |
Shotgun alanine scanning shows that growth hormone can bind productively to its receptor through a drastically minimized interface JLK Kouadio, JR Horn, G Pal, AA Kossiakoff Journal of Biological Chemistry 280 (27), 25524-25532, 2005 | 60 | 2005 |
Affinity purification of recombinant trypsinogen using immobilized ecotin Z Lengyel, G Pál, M Sahin-Tóth Protein expression and purification 12 (2), 291-294, 1998 | 58 | 1998 |
Introduction to practical biochemistry G Hegyi, J Kardos, M Kovács, A Málnási-Csizmadia, L Nyitray, G Pál, ... Eötvös Loránd University, 2013 | 45 | 2013 |