| Chalcone derivatives: promising starting points for drug design MN Gomes, EN Muratov, M Pereira, JC Peixoto, LP Rosseto, PVL Cravo, ... Molecules 22 (8), 1210, 2017 | 370 | 2017 |
| Outbreak of human malaria caused by Plasmodium simium in the Atlantic Forest in Rio de Janeiro: a molecular epidemiological investigation P Brasil, MG Zalis, A de Pina-Costa, AM Siqueira, CB Júnior, S Silva, ... The Lancet Global Health 5 (10), e1038-e1046, 2017 | 301 | 2017 |
| Malaria parasites can develop stable resistance to artemisinin but lack mutations in candidate genes atp6 (encoding the sarcoplasmic and endoplasmic reticulum Ca2+ ATPase … A Afonso, P Hunt, S Cheesman, AC Alves, CV Cunha, V Do Rosário, ... Antimicrobial agents and chemotherapy 50 (2), 480-489, 2006 | 289 | 2006 |
| Gene encoding a deubiquitinating enzyme is mutated in artesunate‐ and chloroquine‐resistant rodent malaria parasites§ P Hunt, A Afonso, A Creasey, R Culleton, ABS Sidhu, J Logan, ... Molecular microbiology 65 (1), 27-40, 2007 | 206 | 2007 |
| Real-time quantitative PCR with SYBR Green I detection for estimating copy numbers of nine drug resistance candidate genes in Plasmodium falciparum ID Ferreira, VE Do Rosário, PVL Cravo Malaria journal 5, 1-6, 2006 | 160 | 2006 |
| Failure to detect Plasmodium vivax in West and Central Africa by PCR species typing RL Culleton, T Mita, M Ndounga, H Unger, PVL Cravo, GM Paganotti, ... Malaria journal 7, 1-8, 2008 | 106 | 2008 |
| Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites P Hunt, A Martinelli, K Modrzynska, S Borges, A Creasey, L Rodrigues, ... BMC genomics 11, 1-13, 2010 | 104 | 2010 |
| Of mice and malaria mutants: unravelling the genetics of drug resistance using rodent malaria models JMR Carlton, K Hayton, PVL Cravo, D Walliker Trends in parasitology 17 (5), 236-242, 2001 | 103 | 2001 |
| Natural products as leads in schistosome drug discovery BJ Neves, CH Andrade, PVL Cravo Molecules 20 (2), 1872-1903, 2015 | 96 | 2015 |
| Emerging Plasmodium vivax resistance to chloroquine in South America: an overview LA Gonçalves, P Cravo, MU Ferreira Memorias do Instituto Oswaldo Cruz 109, 534-539, 2014 | 90 | 2014 |
| Simple and sensitive antimalarial drug screening in vitro and in vivo using transgenic luciferase expressing Plasmodium berghei parasites B Franke-Fayard, D Djokovic, MW Dooren, J Ramesar, AP Waters, ... International journal for parasitology 38 (14), 1651-1662, 2008 | 89 | 2008 |
| Molecular characterisation of drug-resistant Plasmodium falciparum from Thailand D Lopes, K Rungsihirunrat, F Nogueira, A Seugorn, JP Gil, VE Do Rosário, ... Malaria journal 1, 1-11, 2002 | 88 | 2002 |
| Detection of atovaquone and Malarone™ resistance conferring mutations in Plasmodium falciparum cytochrome b gene (cytb) JP Gil, F Nogueira, J Strömberg-Nörklit, J Lindberg, M Carrolo, ... Molecular and cellular probes 17 (2-3), 85-89, 2003 | 73 | 2003 |
| Artemisinin resistance in rodent malaria-mutation in the AP2 adaptor μ-chain suggests involvement of endocytosis and membrane protein trafficking G Henriques, A Martinelli, L Rodrigues, K Modrzynska, R Fawcett, ... Malaria journal 12, 1-15, 2013 | 71 | 2013 |
| Chloroquine resistance in Plasmodium chabaudi: are chloroquine-resistance transporter (crt) and multi-drug resistance (mdr1) orthologues involved? P Hunt, PVL Cravo, P Donleavy, JMR Carlton, D Walliker Molecular and biochemical parasitology 133 (1), 27-35, 2004 | 69 | 2004 |
| Genetics of Mefloquine Resistance in the Rodent Malaria Parasite Plasmodium chabaudi PVL Cravo, JMR Carlton, P Hunt, L Bisoni, RA Padua, D Walliker Antimicrobial agents and chemotherapy 47 (2), 709-718, 2003 | 69 | 2003 |
| Antiplasmodial activity of lignans and extracts from Pycnanthus angolensis M Abrantes, T Mil-Homens, N Duarte, D Lopes, P Cravo, ... Planta medica 74 (11), 1408-1412, 2008 | 68 | 2008 |
| Malaria combination therapies: advantages and shortcomings A Martinelli, R Moreira, PVL Cravo Mini reviews in medicinal chemistry 8 (3), 201-212, 2008 | 63 | 2008 |
| In Silico Repositioning-Chemogenomics Strategy Identifies New Drugs with Potential Activity against Multiple Life Stages of Schistosoma mansoni BJ Neves, RC Braga, JCB Bezerra, PVL Cravo, CH Andrade PLoS Neglected Tropical Diseases 9 (1), e3435, 2015 | 60 | 2015 |
| Plasmodium falciparum from Pará state (Brazil) shows satisfactory in vitro response to artemisinin derivatives and absence of the S769N mutation in the SERCA‐type PfATPase6 ID Ferreira, A Martinelli, LA Rodrigues, EL Do Carmo, VE Do Rosário, ... Tropical Medicine & International Health 13 (2), 199-207, 2008 | 60 | 2008 |
Axel MartinelliInstitute for Research in Biomedicine, Bellinzona在 irb.usi.ch 的电子邮件经过验证
