mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation M Morita, SP Gravel, V Chenard, K Sikström, L Zheng, T Alain, V Gandin, ... Cell metabolism 18 (5), 698-711, 2013 | 822 | 2013 |
La-related protein 1 (LARP1) represses terminal oligopyrimidine (TOP) mRNA translation downstream of mTOR complex 1 (mTORC1) BD Fonseca, C Zakaria, JJ Jia, TE Graber, Y Svitkin, S Tahmasebi, ... Journal of Biological Chemistry 290 (26), 15996-16020, 2015 | 276 | 2015 |
S6K-STING interaction regulates cytosolic DNA–mediated activation of the transcription factor IRF3 F Wang, T Alain, KJ Szretter, K Stephenson, JG Pol, MJ Atherton, ... Nature immunology 17 (5), 514-522, 2016 | 86 | 2016 |
Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing R Arulanandam, C Batenchuk, O Varette, C Zakaria, V Garcia, NE Forbes, ... Nature communications 6 (1), 6410, 2015 | 62 | 2015 |
The endonuclease IV family of apurinic/apyrimidinic endonucleases JM Daley, C Zakaria, D Ramotar Mutation Research/Reviews in Mutation Research 705 (3), 217-227, 2010 | 61 | 2010 |
Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis C Zakaria, P Sean, HD Hoang, LP Leroux, M Watson, ST Workenhe, ... PLoS Pathogens 14 (8), e1007264, 2018 | 29 | 2018 |
Metformin requires 4E-BPs to induce apoptosis and repress translation of Mcl-1 in hepatocellular carcinoma cells M Bhat, A Yanagiya, T Graber, N Razumilava, S Bronk, D Zammit, Y Zhao, ... Oncotarget 8 (31), 50542, 2017 | 26 | 2017 |
Caenorhabditis elegans APN-1 plays a vital role in maintaining genome stability C Zakaria, H Kassahun, X Yang, JC Labbé, H Nilsen, D Ramotar DNA repair 9 (2), 169-176, 2010 | 26 | 2010 |
La-related protein 1 (LARP1) represses terminal oligopyrimidine (TOP) mRNA translation downstream of mTOR complex 1 (mTORC1) J Biol Chem. 2015; 290 (26): 15996–16020. doi: 10 … BD Fonseca, C Zakaria, JJ Jia, TE Graber, Y Svitkin, S Tahmasebi, ... M114 621730, 0 | 13 | |
Molecular targeting of the UDP-glucuronosyltransferase enzymes in high-eukaryotic translation initiation factor 4E refractory/relapsed acute myeloid leukemia patients: a … S Assouline, J Gasiorek, J Bergeron, C Lambert, B Culjkovic-Kraljacic, ... Haematologica 108 (11), 2946, 2023 | 5 | 2023 |
Exploring the effects and effectors of mTOR inhibition in oncolysis and TOP mRNA translation C Zakaria McGill University (Canada), 2018 | 1 | 2018 |
The in vivo characterization of the DNA repair gene apn-1 in the model organism Caenorhabditis elegans C Zakaria | | 2010 |
Supplemental Information mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation M Morita, SP Gravel, V Chénard, K Sikström, L Zheng, T Alain, V Gandin, ... | | |
Best of Supplement—Cell Metabolism Best of 2013 M Morita, SP Gravel, V Chénard, K Sikström, L Zheng, T Alain, V Gandin, ... | | |