Predicting the energetics of osmolyte-induced protein folding/unfolding M Auton, DW Bolen Proceedings of the National Academy of Sciences 102 (42), 15065-15068, 2005 | 511 | 2005 |
Anatomy of energetic changes accompanying urea-induced protein denaturation M Auton, LMF Holthauzen, DW Bolen Proceedings of the National Academy of Sciences 104 (39), 15317-15322, 2007 | 331 | 2007 |
Osmolyte effects on protein stability and solubility: A balancing act between backbone and side-chains M Auton, J Rösgen, M Sinev, LMF Holthauzen, DW Bolen Biophysical chemistry 159 (1), 90-99, 2011 | 262 | 2011 |
Additive transfer free energies of the peptide backbone unit that are independent of the model compound and the choice of concentration scale M Auton, DW Bolen Biochemistry 43 (5), 1329-1342, 2004 | 252 | 2004 |
Structural thermodynamics of protein preferential solvation: osmolyte solvation of proteins, aminoacids, and peptides M Auton, DW Bolen, J Rösgen Proteins: Structure, Function, and Bioinformatics 73 (4), 802-813, 2008 | 202 | 2008 |
Application of the transfer model to understand how naturally occurring osmolytes affect protein stability M Auton, DW Bolen Methods in enzymology 428, 397-418, 2007 | 116 | 2007 |
Conformational stability and domain unfolding of the Von Willebrand factor A domains M Auton, MA Cruz, J Moake Journal of molecular biology 366 (3), 986-1000, 2007 | 112 | 2007 |
Metrics that differentiate the origins of osmolyte effects on protein stability: a test of the surface tension proposal M Auton, ACM Ferreon, DW Bolen Journal of molecular biology 361 (5), 983-992, 2006 | 108 | 2006 |
Kinetic control in protein folding for light chain amyloidosis and the differential effects of somatic mutations LM Blancas-Mejía, A Tischer, JR Thompson, J Tai, L Wang, M Auton, ... Journal of molecular biology 426 (2), 347-361, 2014 | 59 | 2014 |
N-terminal flanking region of A1 domain in von Willebrand factor stabilizes structure of A1A2A3 complex and modulates platelet activation under shear stress M Auton, KE Sowa, M Behymer, MA Cruz Journal of Biological Chemistry 287 (18), 14579-14585, 2012 | 59 | 2012 |
The mechanism of VWF-mediated platelet GPIbα binding M Auton, C Zhu, MA Cruz Biophysical journal 99 (4), 1192-1201, 2010 | 56 | 2010 |
Thermodynamic and fibril formation studies of full length immunoglobulin light chain AL-09 and its germline protein using scan rate dependent thermal unfolding LM Blancas-Mejía, TJ Horn, M Marin-Argany, M Auton, A Tischer, ... Biophysical chemistry 207, 13-20, 2015 | 52 | 2015 |
Destabilization of the A1 domain in von Willebrand factor dissociates the A1A2A3 tri-domain and provokes spontaneous binding to glycoprotein Ibα and platelet activation under … M Auton, KE Sowa, SM Smith, E Sedlák, KV Vijayan, MA Cruz Journal of Biological Chemistry 285 (30), 22831-22839, 2010 | 52 | 2010 |
Changes in thermodynamic stability of von Willebrand factor differentially affect the force-dependent binding to platelet GPIbα M Auton, E Sedlák, J Marek, T Wu, C Zhu, MA Cruz Biophysical journal 97 (2), 618-627, 2009 | 48 | 2009 |
The linker between the d3 and a1 domains of vwf suppresses a1‐GPIbα catch bonds by site‐specific binding to the a1 domain A Tischer, MA Cruz, M Auton Protein Science 22 (8), 1049-1059, 2013 | 41 | 2013 |
Misfolding of vWF to pathologically disordered conformations impacts the severity of von Willebrand disease A Tischer, P Madde, L Moon-Tasson, M Auton Biophysical journal 107 (5), 1185-1195, 2014 | 40 | 2014 |
Alanine and proline content modulate global sensitivity to discrete perturbations in disordered proteins RB Perez, A Tischer, M Auton, ST Whitten Proteins: Structure, Function, and Bioinformatics 82 (12), 3373-3384, 2014 | 37 | 2014 |
The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction R Schneppenheim, N Hellermann, MA Brehm, U Klemm, T Obser, V Huck, ... Blood, The Journal of the American Society of Hematology 133 (4), 356-365, 2019 | 34 | 2019 |
Mutational constraints on local unfolding inhibit the rheological adaptation of von Willebrand factor A Tischer, JC Campbell, VR Machha, L Moon-Tasson, LM Benson, ... Journal of Biological Chemistry 291 (8), 3848-3859, 2016 | 31 | 2016 |
Protein stability in the presence of cosolutes LMF Holthauzen, M Auton, M Sinev, J Rösgen Methods in Enzymology 492, 61-125, 2011 | 31 | 2011 |