Eigenvector centrality for characterization of protein allosteric pathways CFA Negre, UN Morzan, HP Hendrickson, R Pal, GP Lisi, JP Loria, ... Proceedings of the National Academy of Sciences 115 (52), E12201-E12208, 2018 | 202 | 2018 |
Solution NMR spectroscopy for the study of enzyme allostery GP Lisi, JP Loria Chemical reviews 116 (11), 6323-6369, 2016 | 127 | 2016 |
Allosteric motions of the CRISPR–Cas9 HNH nuclease probed by NMR and molecular dynamics KW East, JC Newton, UN Morzan, YB Narkhede, A Acharya, E Skeens, ... Journal of the American Chemical Society 142 (3), 1348-1358, 2019 | 84 | 2019 |
Allostery in enzyme catalysis GP Lisi, JP Loria Current Opinion in Structural Biology 47, 123-130, 2017 | 68 | 2017 |
A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch JF Amacher, F Zhong, GP Lisi, MQ Zhu, SL Alden, KR Hoke, DR Madden, ... Journal of the American Chemical Society 137 (26), 8435-8449, 2015 | 63 | 2015 |
Altering the allosteric pathway in IGPS suppresses millisecond motions and catalytic activity GP Lisi, KW East, VS Batista, JP Loria Proceedings of the National Academy of Sciences 114 (17), E3414-E3423, 2017 | 58 | 2017 |
Redox-dependent stability, protonation, and reactivity of cysteine-bound heme proteins F Zhong, GP Lisi, DP Collins, JH Dawson, EV Pletneva Proceedings of the National Academy of Sciences 111 (3), E306-E315, 2014 | 55 | 2014 |
Using NMR spectroscopy to elucidate the role of molecular motions in enzyme function GP Lisi, JP Loria Progress in nuclear magnetic resonance spectroscopy 92, 1-17, 2016 | 50 | 2016 |
Allosteric communication disrupted by a small molecule binding to the imidazole glycerol phosphate synthase protein–protein interface I Rivalta, GP Lisi, NS Snoeberger, G Manley, JP Loria, VS Batista Biochemistry 55 (47), 6484-6494, 2016 | 43 | 2016 |
Dissecting dynamic allosteric pathways using chemically related small-molecule activators GP Lisi, GA Manley, H Hendrickson, I Rivalta, VS Batista, JP Loria Structure 24 (7), 1155-1166, 2016 | 43 | 2016 |
Novel biomarkers of hepatitis B virus and their use in chronic hepatitis B patient management A Vachon, C Osiowy Viruses 13 (6), 951, 2021 | 41 | 2021 |
Syntheses, characterization, density functional theory calculations, and activity of tridentate SNS zinc pincer complexes based on bis-imidazole or bis-triazole precursors JR Miecznikowski, W Lo, MA Lynn, S Jain, LC Keilich, NF Kloczko, ... Inorganica Chimica Acta 387, 25-36, 2012 | 41 | 2012 |
NMR and computational methods for molecular resolution of allosteric pathways in enzyme complexes KW East, E Skeens, JY Cui, HB Belato, B Mitchell, R Hsu, VS Batista, ... Biophysical reviews 12 (1), 155-174, 2020 | 39 | 2020 |
Thermodynamic contributions to the stability of the insulin hexamer GP Lisi, CYM Png, DE Wilcox Biochemistry 53 (22), 3576-3584, 2014 | 33 | 2014 |
Glutamine hydrolysis by imidazole glycerol phosphate synthase displays temperature dependent allosteric activation GP Lisi, AA Currier, JP Loria Frontiers in Molecular Biosciences 5, 4, 2018 | 30 | 2018 |
Syntheses, characterization, density functional theory calculations, and activity of tridentate SNS zinc pincer complexes JR Miecznikowski, W Lo, MA Lynn, BE O’Loughlin, AP DiMarzio, ... Inorganica Chimica Acta 376 (1), 515-524, 2011 | 29 | 2011 |
Enhanced specificity mutations perturb allosteric signaling in CRISPR-Cas9 L Nierzwicki, KW East, UN Morzan, PR Arantes, VS Batista, GP Lisi, ... Elife 10, e73601, 2021 | 28 | 2021 |
Regulation of MIF enzymatic activity by an allosteric site at the central solvent channel G Pantouris, L Khurana, A Ma, E Skeens, K Reiss, VS Batista, GP Lisi, ... Cell chemical biology 27 (6), 740-750. e5, 2020 | 27 | 2020 |
Principles of target DNA cleavage and the role of Mg2+ in the catalysis of CRISPR–Cas9 Ł Nierzwicki, KW East, JM Binz, RV Hsu, M Ahsan, PR Arantes, E Skeens, ... Nature catalysis 5 (10), 912-922, 2022 | 24 | 2022 |
Mechanism of Inhibition of the Reproduction of SARS-CoV-2 and Ebola Viruses by Remdesivir J Wang, K Reiss, Y Shi, E Lolis, GP Lisi, VS Batista Biochemistry 60 (24), 1869-1875, 2021 | 17 | 2021 |