Peroxisome proliferator-activated receptor α negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-κB and AP-1 P Delerive, K De Bosscher, S Besnard, WV Berghe, JM Peters, ... Journal of Biological Chemistry 274 (45), 32048-32054, 1999 | 1380 | 1999 |
The interplay between the glucocorticoid receptor and nuclear factor-κB or activator protein-1: molecular mechanisms for gene repression K De Bosscher, W Vanden Berghe, G Haegeman Endocrine reviews 24 (4), 488-522, 2003 | 1198 | 2003 |
Transcriptional activation of the NF‐κB p65 subunit by mitogen‐and stress‐activated protein kinase‐1 (MSK1) L Vermeulen, G De Wilde, P Van Damme, WV Berghe, G Haegeman The EMBO journal, 2003 | 966 | 2003 |
p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor WV Berghe, S Plaisance, E Boone, K De Bosscher, ML Schmitz, W Fiers, ... Journal of Biological Chemistry 273 (6), 3285-3290, 1998 | 834 | 1998 |
The p38/RK mitogen‐activated protein kinase pathway regulates interleukin‐6 synthesis response to tumor necrosis factor. R Beyaert, A Cuenda, W Vanden Berghe, S Plaisance, JC Lee, ... The EMBO journal 15 (8), 1914-1923, 1996 | 814 | 1996 |
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma B Hassannia, B Wiernicki, I Ingold, K Declerck, CS Chirumamilla, ... The journal of clinical investigation., 1-16, 2018 | 488 | 2018 |
Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation K De Bosscher, ML Schmitz, W Vanden Berghe, S Plaisance, W Fiers, ... Proceedings of the National Academy of Sciences 94 (25), 13504-13509, 1997 | 462 | 1997 |
How glucocorticoid receptors modulate the activity of other transcription factors: a scope beyond tethering D Ratman, WV Berghe, L Dejager, C Libert, J Tavernier, IM Beck, ... Molecular and cellular endocrinology 380 (1-2), 41-54, 2013 | 461 | 2013 |
Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell K De Bosscher, W Vanden Berghe, L Vermeulen, S Plaisance, E Boone, ... Proceedings of the National Academy of Sciences 97 (8), 3919-3924, 2000 | 432 | 2000 |
The nuclear factor-κB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter WV Berghe, K De Bosscher, E Boone, S Plaisance, G Haegeman Journal of Biological Chemistry 274 (45), 32091-32098, 1999 | 423 | 1999 |
Regulation of the transcriptional activity of the nuclear factor-κB p65 subunit L Vermeulen, G De Wilde, S Notebaert, WV Berghe, G Haegeman Biochemical pharmacology 64 (5-6), 963-970, 2002 | 405 | 2002 |
The zinc finger protein A20 inhibits TNF-induced NF-κB–dependent gene expression by interfering with an RIP-or TRAF2-mediated transactivation signal and directly binds to a … K Heyninck, D De Valck, WV Berghe, W Van Criekinge, R Contreras, ... The Journal of cell biology 145 (7), 1471-1482, 1999 | 396 | 1999 |
Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: negative interference of activated glucocorticoid receptor with transcription factors K De Bosscher, WV Berghe, G Haegeman Journal of neuroimmunology 109 (1), 16-22, 2000 | 393 | 2000 |
Signal transduction by tumor necrosis factor and gene regulation of the inflammatory cytokine interleukin-6 WV Berghe, L Vermeulen, G De Wilde, K De Bosscher, E Boone, ... Biochemical pharmacology 60 (8), 1185-1195, 2000 | 391 | 2000 |
Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases IME Beck, W Vanden Berghe, L Vermeulen, KR Yamamoto, G Haegeman, ... Endocrine reviews 30 (7), 830-882, 2009 | 357 | 2009 |
A fully dissociated compound of plant origin for inflammatory gene repression K De Bosscher, WV Berghe, IME Beck, W Van Molle, N Hennuyer, ... Proceedings of the National Academy of Sciences 102 (44), 15827-15832, 2005 | 336 | 2005 |
Cross-talk between nuclear receptors and nuclear factor κB K De Bosscher, W Vanden Berghe, G Haegeman Oncogene 25 (51), 6868-6886, 2006 | 335 | 2006 |
Withaferin A strongly elicits IκB kinase β hyperphosphorylation concomitant with potent inhibition of its kinase activity M Kaileh, WV Berghe, A Heyerick, J Horion, J Piette, C Libert, ... Journal of Biological Chemistry 282 (7), 4253-4264, 2007 | 334 | 2007 |
Screening of indigenous Palestinian medicinal plants for potential anti-inflammatory and cytotoxic activity M Kaileh, WV Berghe, E Boone, T Essawi, G Haegeman Journal of ethnopharmacology 113 (3), 510-516, 2007 | 304 | 2007 |
A paradigm for gene regulation: inflammation, NF-κB and PPAR W Vanden Berghe, L Vermeulen, P Delerive, K De Bosscher, B Staels, ... Peroxisomal disorders and regulation of genes, 181-196, 2003 | 298 | 2003 |