Predictive markers guide differentiation to improve graft outcome in clinical translation of hESC-based therapy for Parkinson’s disease A Kirkeby, S Nolbrant, K Tiklova, A Heuer, N Kee, T Cardoso, ... Cell stem cell 20 (1), 135-148, 2017 | 281 | 2017 |
Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation S Nolbrant, A Heuer, M Parmar, A Kirkeby Nature protocols 12 (9), 1962-1979, 2017 | 225 | 2017 |
Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development K Tiklová, ÅK Björklund, L Lahti, A Fiorenzano, S Nolbrant, L Gillberg, ... Nature communications 10 (1), 581, 2019 | 215 | 2019 |
Single-cell analysis reveals a close relationship between differentiating dopamine and subthalamic nucleus neuronal lineages N Kee, N Volakakis, A Kirkeby, L Dahl, H Storvall, S Nolbrant, L Lahti, ... Cell stem cell 20 (1), 29-40, 2017 | 147 | 2017 |
A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism M Davidsson, G Wang, P Aldrin-Kirk, T Cardoso, S Nolbrant, M Hartnor, ... Proceedings of the National Academy of Sciences 116 (52), 27053-27062, 2019 | 141 | 2019 |
Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease K Tiklová, S Nolbrant, A Fiorenzano, ÅK Björklund, Y Sharma, A Heuer, ... Nature communications 11 (1), 2434, 2020 | 93 | 2020 |
hESC-derived dopaminergic transplants integrate into basal ganglia circuitry in a preclinical model of Parkinson’s disease AF Adler, T Cardoso, S Nolbrant, B Mattsson, DB Hoban, U Jarl, ... Cell reports 28 (13), 3462-3473. e5, 2019 | 82 | 2019 |
Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of Parkinsonian rats T Cardoso, AF Adler, B Mattsson, DB Hoban, S Nolbrant, JN Wahlestedt, ... Journal of Comparative Neurology 526 (13), 2133-2146, 2018 | 58 | 2018 |
Direct reprogramming of human fetal-and stem cell-derived glial progenitor cells into midbrain dopaminergic neurons S Nolbrant, J Giacomoni, DB Hoban, A Bruzelius, M Birtele, ... Stem Cell Reports 15 (4), 869-882, 2020 | 24 | 2020 |
Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery Z Alekseenko, JM Dias, AF Adler, M Kozhevnikova, JA van Lunteren, ... Nature Communications 13 (1), 3046, 2022 | 14 | 2022 |
Profiling of lincRNAs in human pluripotent stem cell derived forebrain neural progenitor cells DA Grassi, PL Brattås, ME Jönsson, D Atacho, O Karlsson, S Nolbrant, ... Heliyon 6 (1), 2020 | 13 | 2020 |
The putative tumor suppressor gene EphA7 is a novel BMI-1 target G Prost, S Braun, F Hertwig, M Winkler, L Jagemann, S Nolbrant, IV Leefa, ... Oncotarget 7 (36), 58203, 2016 | 10 | 2016 |
Single cell gene expression analysis reveals human stem cell-derived graft composition in a cell therapy model of Parkinson’s disease K Tiklová, S Nolbrant, A Fiorenzano, ÅK Björklund, Y Sharma, A Heuer, ... bioRxiv, 720870, 2019 | 7 | 2019 |
Barcoded Rational AAV Vector Evolution enables systematic in vivo mapping of peptide binding motifs M Davidsson, G Wang, P Aldrin-Kirk, T Cardoso, S Nolbrant, M Hartnor, ... bioRxiv, 335372, 2018 | 7 | 2018 |
Human embryonic stem cell-derived dopaminergic grafts alleviate L-DOPA induced dyskinesia OF Elabi, R Pass, I Sormonta, S Nolbrant, N Drummond, A Kirkeby, ... Journal of Parkinson's disease 12 (6), 1881-1896, 2022 | 6 | 2022 |
A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants P Aldrin-Kirk, M Åkerblom, T Cardoso, S Nolbrant, AF Adler, X Liu, ... Stem Cell Reports 17 (1), 159-172, 2022 | 5 | 2022 |
Neural tube patterning: From a minimal model for rostrocaudal patterning toward an integrated 3D model M Brambach, A Ernst, S Nolbrant, J Drouin-Ouellet, A Kirkeby, M Parmar, ... Iscience 24 (6), 2021 | 3 | 2021 |
Post-transcriptional mechanisms distinguish human and chimp forebrain progenitor cells DA Grassi, PL Brattås, JG Valdés, M Rezeli, ME Jönsson, S Nolbrant, ... bioRxiv, 582197, 2019 | 3 | 2019 |
Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants in vivo J Rájová, M Davidsson, M Avallone, M Hartnor, P Aldrin-Kirk, T Cardoso, ... Molecular Therapy Methods & Clinical Development 29, 381-394, 2023 | 2 | 2023 |
Unbiased Gene Expression Analysis Reveals Human Stem Cell-Derived Graft Composition in a Cell Therapy Model of Parkinson's Disease S Nolbrant, K Tiklova, A Fiorenzano, AK Bjorklund, Y Sharma, A Heuer, ... CELL TRANSPLANTATION 30, 16-16, 2021 | | 2021 |