Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display DM Shechner, E Hacisuleyman, ST Younger, JL Rinn Nature methods 12 (7), 664-670, 2015 | 328 | 2015 |
Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs M Melé, K Mattioli, W Mallard, DM Shechner, C Gerhardinger, JL Rinn Genome research 27 (1), 27-37, 2017 | 256 | 2017 |
Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking P Kaewsapsak, DM Shechner, W Mallard, JL Rinn, AY Ting Elife 6, e29224, 2017 | 173 | 2017 |
Directed evolution of split APEX2 peroxidase Y Han, TC Branon, JD Martell, D Boassa, D Shechner, MH Ellisman, ... ACS Chemical Biology 14 (4), 619-635, 2019 | 154 | 2019 |
Crystal structure of the catalytic core of an RNA-polymerase ribozyme DM Shechner, RA Grant, SC Bagby, Y Koldobskaya, JA Piccirilli, ... Science 326 (5957), 1271-1275, 2009 | 143 | 2009 |
High‐throughput identification of RNA nuclear enrichment sequences CJ Shukla, AL McCorkindale, C Gerhardinger, KD Korthauer, MN Cabili, ... The EMBO journal 37 (6), e98452, 2018 | 114 | 2018 |
Spatiotemporal allele organization by allele-specific CRISPR live-cell imaging (SNP-CLING) PG Maass, AR Barutcu, DM Shechner, CL Weiner, M Melé, JL Rinn Nature structural & molecular biology 25 (2), 176-184, 2018 | 92 | 2018 |
A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination Y Koldobskaya, EM Duguid, DM Shechner, NB Suslov, J Ye, SS Sidhu, ... Nature structural & molecular biology 18 (1), 100-106, 2011 | 89 | 2011 |
The structural basis of RNA-catalyzed RNA polymerization DM Shechner, DP Bartel Nature structural & molecular biology 18 (9), 1036-1042, 2011 | 54 | 2011 |
A class I ligase ribozyme with reduced Mg2+ dependence: Selection, sequence analysis, and identification of functional tertiary interactions SC Bagby, NH Bergman, DM Shechner, C Yen, DP Bartel Rna 15 (12), 2129-2146, 2009 | 25 | 2009 |
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo DM Shechner, E Hacisüleyman, ST Younger, JL Rinn Nature methods 12 (7), 664, 2015 | 10 | 2015 |
‘Morphs’(MRFs): metal-reversible folding domains for differential IgG binding SF Marino, D Shechner, L Regan Chemistry & biology 8 (12), 1221-1229, 2001 | 9 | 2001 |
Oligonucleotide-directed proximity-interactome mapping (O-MAP): A unified method for discovering RNA-interacting proteins, transcripts and genomic loci in situ AF Tsue, EE Kania, DQ Lei, R Fields, CD McGann, E Hershberg, X Deng, ... bioRxiv, 2023.01. 19.524825, 2023 | 6 | 2023 |
Methods of making and using guide RNA for use with Cas9 systems JL Rinn, DM Shechner US Patent 10,920,221, 2021 | 4 | 2021 |
High-Throughput Identification of Calcium Regulated Proteins Across Diverse Proteomes TM Locke, R Fields, H Gizinski, GM Otto, DM Shechner, MD Berg, J Villen, ... bioRxiv, 2024 | 1 | 2024 |
Programmable peroxidase-assisted signal amplification enables flexible detection of nucleic acid targets in cellular and histopathological specimens S Attar, VE Browning, Y Liu, EK Nichols, AF Tsue, DM Shechner, ... bioRxiv, 2023.01. 30.526264, 2023 | 1 | 2023 |
Targeting Noncoding RNA Domains to Genomic Loci with CRISPR-Display: Guidelines for Designing, Building, and Testing sgRNA–ncRNA Expression Constructs DM Shechner CRISPR Guide RNA Design: Methods and Protocols, 115-152, 2021 | 1 | 2021 |
DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci Y Liu, CD McGann, M Krebs, TA Perkins Jr, R Fields, CK Camplisson, ... bioRxiv, 2024.07. 24.604987, 2024 | | 2024 |
Architecture of an RNA polymerase ribozyme illuminates the RNA World DM Shechner Trends in Genetics, 2024 | | 2024 |
Efficient and highly amplified imaging of nucleic acid targets in cellular and histopathological samples with pSABER S Attar, VE Browning, Y Liu, EK Nichols, AF Tsue, DM Shechner, ... bioRxiv, 2023.01. 30.526264, 2023 | | 2023 |