| The dopamine hypothesis of reward: past and current status R Spanagel, F Weiss Trends in neurosciences 22 (11), 521-527, 1999 | 1324 | 1999 |
| Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. R Spanagel, A Herz, TS Shippenberg Proceedings of the National Academy of Sciences 89 (6), 2046-2050, 1992 | 1228 | 1992 |
| Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1 P Timpl, R Spanagel, I Sillaber, A Kresse, JMHM Reul, GK Stalla, ... Nature genetics 19 (2), 162-166, 1998 | 1105 | 1998 |
| Alcoholism: a systems approach from molecular physiology to addictive behavior R Spanagel Physiological reviews 89 (2), 649-705, 2009 | 805 | 2009 |
| Behavioural assessment of drug reinforcement and addictive features in rodents: an overview C Sanchis‐Segura, R Spanagel Addiction biology 11 (1), 2-38, 2006 | 763 | 2006 |
| Neuropharmacology of alcohol addiction V Vengeliene, A Bilbao, A Molander, R Spanagel British journal of pharmacology 154 (2), 299-315, 2008 | 735 | 2008 |
| The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology G Schumann, E Loth, T Banaschewski, A Barbot, G Barker, C Büchel, ... Molecular psychiatry 15 (12), 1128-1139, 2010 | 697 | 2010 |
| The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption R Spanagel, G Pendyala, C Abarca, T Zghoul, C Sanchis-Segura, ... Nature medicine 11 (1), 35-42, 2005 | 684 | 2005 |
| The effects of opioid peptides on dopamine release in the nucleus accumbens: an in vivo microdialysis study R Spanagel, A Herz, TS Shippenberg Journal of neurochemistry 55 (5), 1734-1740, 1990 | 670 | 1990 |
| Stress-induced anhedonia in mice is associated with deficits in forced swimming and exploration T Strekalova, R Spanagel, D Bartsch, FA Henn, P Gass Neuropsychopharmacology 29 (11), 2007-2017, 2004 | 664 | 2004 |
| Correlated gene expression supports synchronous activity in brain networks J Richiardi, A Altmann, AC Milazzo, C Chang, MM Chakravarty, ... Science 348 (6240), 1241-1244, 2015 | 611 | 2015 |
| Cocaine sensitization and reward are under the influence of circadian genes and rhythm C Abarca, U Albrecht, R Spanagel Proceedings of the National Academy of Sciences 99 (13), 9026-9030, 2002 | 546 | 2002 |
| Adolescent impulsivity phenotypes characterized by distinct brain networks R Whelan, PJ Conrod, JB Poline, A Lourdusamy, T Banaschewski, ... Nature neuroscience 15 (6), 920-925, 2012 | 490 | 2012 |
| Neuropsychosocial profiles of current and future adolescent alcohol misusers R Whelan, R Watts, CA Orr, RR Althoff, E Artiges, T Banaschewski, ... Nature 512 (7513), 185-189, 2014 | 480 | 2014 |
| Withdrawal phenomena and dependence syndrome after the consumption of" spice gold" US Zimmermann, PR Winkelmann, M Pilhatsch, JA Nees, R Spanagel, ... Deutsches Ärzteblatt International 106 (27), 464, 2009 | 474 | 2009 |
| Genome-wide association study of alcohol dependence J Treutlein, S Cichon, M Ridinger, N Wodarz, M Soyka, P Zill, W Maier, ... Archives of general psychiatry 66 (7), 773-784, 2009 | 457 | 2009 |
| Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood G Hampp, JA Ripperger, T Houben, I Schmutz, C Blex, S Perreau-Lenz, ... Current Biology 18 (9), 678-683, 2008 | 457 | 2008 |
| Impaired long-term memory and NR2A-type NMDA receptor-dependent synaptic plasticity in mice lacking c-Fos in the CNS A Fleischmann, O Hvalby, V Jensen, T Strekalova, C Zacher, LE Layer, ... Journal of Neuroscience 23 (27), 9116-9122, 2003 | 441 | 2003 |
| Anti-craving compounds for ethanol: new pharmacological tools to study addictive processes R Spanagel, W Zieglgänsberger Trends in pharmacological sciences 18 (2), 54-59, 1997 | 438 | 1997 |
| Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc M Mameli, B Halbout, C Creton, D Engblom, JR Parkitna, R Spanagel, ... Nature neuroscience 12 (8), 1036-1041, 2009 | 376 | 2009 |
