The kinesin KIF1Bβ acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor S Schlisio, RS Kenchappa, LCW Vredeveld, RE George, R Stewart, ... Genes & development 22 (7), 884, 2008 | 407 | 2008 |
Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons RS Kenchappa, N Zampieri, MV Chao, PA Barker, HK Teng, ... Neuron 50 (2), 219-232, 2006 | 240 | 2006 |
Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures M Volosin, C Trotter, A Cragnolini, RS Kenchappa, M Light, ... Journal of neuroscience 28 (39), 9870-9879, 2008 | 205 | 2008 |
Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers M Vilar*, I Charalampopoulos*, RS Kenchappa*, A Simi, E Karaca, ... Neuron 62 (1), 72-83, 2009 | 199 | 2009 |
p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-α-converting enzyme/ADAM17 RS Kenchappa, C Tep, Z Korade, S Urra, FC Bronfman, SO Yoon, ... Journal of Biological Chemistry 285 (26), 20358-20368, 2010 | 170 | 2010 |
P75NTR mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up regulation of TACE/ADAM17 RS Kenchappa, C Tep, Z Korade, S Urra, FC Bronfman, SO Yoon, ... Journal of Biological Chemistry, jbc. M109. 082834, 2010 | 170 | 2010 |
Neurotrophin signaling via TrkB and TrkC Receptors promote the growth of Brain Tumor Initiating Cells S Lawn, N Krishna, A Pisklakova, X Qu, DA Fenstermacher, M Fournier, ... Journal of Biological Chemistry 290 (6), 3814-3824, 2015 | 148 | 2015 |
TRAF6‐mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor T Geetha*, RS Kenchappa*, MW Wooten, BD Carter The EMBO journal 24 (22), 3859-3868, 2005 | 125 | 2005 |
Protein thiol oxidation by haloperidol results in inhibition of mitochondrial complex I in brain regions: comparison with atypical antipsychotics S Balijepalli, RS Kenchappa, MR Boyd, V Ravindranath Neurochemistry international 38 (5), 425-435, 2001 | 115 | 2001 |
Glutaredoxin is essential for maintenance of brain mitochondrial complex I: studies with MPTP RS Kenchappa, V Ravindranath The FASEB Journal 17 (6), 717-719, 2003 | 101 | 2003 |
A promiscuous liaison between IL‐15 receptor and Axl receptor tyrosine kinase in cell death control V Budagian, E Bulanova, Z Orinska, L Thon, U Mamat, P Bellosta, ... The EMBO journal 24 (24), 4260-4270, 2005 | 100 | 2005 |
Estrogen and neuroprotection: higher constitutive expression of glutaredoxin in female mice offers protection against MPTP‐mediated neurodegeneration RS Kenchappa, L Diwakar, J Annepu, V Ravindranath The FASEB journal 18 (10), 1102-1104, 2004 | 100 | 2004 |
NRAGE, a p75NTR adaptor protein, is required for developmental apoptosis in vivo MJM Bertrand, RS Kenchappa, D Andrieu, M Leclercq-Smekens, ... Cell Death & Differentiation 15 (12), 1921-1929, 2008 | 92 | 2008 |
Ligand-independent signaling by disulfide-crosslinked dimers of the p75 neurotrophin receptor M Vilar, I Charalampopoulos, RS Kenchappa, A Reversi, ... Journal of cell science 122 (18), 3351, 2009 | 78 | 2009 |
BIRC3 is a novel driver of therapeutic resistance in Glioblastoma D Wang, A Berglund, RS Kenchappa, PA Forsyth, JJ Mulé, AB Etame Scientific reports 6 (1), 21710, 2016 | 76 | 2016 |
Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility D Astuti, CJ Ricketts, R Chowdhury, MA McDonough, D Gentle, G Kirby, ... Endocrine-related cancer 18 (1), 73, 2011 | 73 | 2011 |
p75 neurotrophin receptor cleavage by α-and γ-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells PA Forsyth, N Krishna, S Lawn, JG Valadez, X Qu, DA Fenstermacher, ... Journal of Biological Chemistry 289 (12), 8067-8085, 2014 | 67 | 2014 |
Managing leptomeningeal melanoma metastases in the era of immune and targeted therapy KSM Smalley, IV Fedorenko, RS Kenchappa, S Sahebjam, PA Forsyth International journal of cancer 139 (6), 1195-1201, 2016 | 55 | 2016 |
M011L-deficient oncolytic myxoma virus induces apoptosis in brain tumor-initiating cells and enhances survival in a novel immunocompetent mouse model of glioblastoma A Pisklakova, B McKenzie, F Zemp, X Lun, RS Kenchappa, AB Etame, ... Neuro-oncology 18 (8), 1088-1098, 2016 | 51 | 2016 |
RNA helicase A is a downstream mediator of KIF1Bβ tumor-suppressor function in neuroblastoma ZX Chen, K Wallis, SM Fell, VR Sobrado, MC Hemmer, D Ramsköld, ... Cancer discovery 4 (4), 434-451, 2014 | 51 | 2014 |