Regulation of cellular iron metabolism J Wang, K Pantopoulos Biochemical Journal 434 (Pt 3), 365, 2011 | 1201 | 2011 |
Dependence of mouse embryonic stem cells on threonine catabolism J Wang, P Alexander, L Wu, R Hammer, O Cleaver, SL McKnight Science 325 (5939), 435-439, 2009 | 405 | 2009 |
Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53 J Wang, J Shou, X Chen Oncogene 19 (14), 1843-1848, 2000 | 222 | 2000 |
Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity J Wang, G Chen, M Muckenthaler, B Galy, MW Hentze, K Pantopoulos Molecular and cellular biology 24 (3), 954-965, 2004 | 154 | 2004 |
p73 is transcriptionally regulated by DNA damage, p53, and p73 X Chen, Y Zheng, J Zhu, J Jiang, J Wang Oncogene 20 (6), 769-774, 2001 | 123 | 2001 |
p53 induces TAP1 and enhances the transport of MHC class I peptides. K Zhu, J Wang, J Zhu, J Jiang, J Shou, X Chen Oncogene 18 (54), 7740, 1999 | 119 | 1999 |
Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2 Y Zhang, Y Qian, J Zhang, W Yan, YS Jung, M Chen, E Huang, K Lloyd, ... Genes & development 31 (12), 1243-1256, 2017 | 108 | 2017 |
Myeloperoxidase-derived hypochlorous acid antagonizes the oxidative stress-mediated activation of iron regulatory protein 1 S Mütze, U Hebling, W Stremmel, J Wang, J Arnhold, K Pantopoulos, ... Journal of Biological Chemistry 278 (42), 40542-40549, 2003 | 102 | 2003 |
Iron-dependent degradation of apo-IRP1 by the ubiquitin-proteasome pathway J Wang, C Fillebeen, G Chen, A Biederbick, R Lill, K Pantopoulos Molecular and cellular biology 27 (7), 2423-2430, 2007 | 82 | 2007 |
Conditional derepression of ferritin synthesis in cells expressing a constitutive IRP1 mutant J Wang, K Pantopoulos Molecular and cellular biology 22 (13), 4638-4651, 2002 | 69 | 2002 |
Overexpression of iron regulatory protein 1 suppresses growth of tumor xenografts G Chen, C Fillebeen, J Wang, K Pantopoulos Carcinogenesis 28 (4), 785-791, 2006 | 67 | 2006 |
Serine catabolism is essential to maintain mitochondrial respiration in mammalian cells S Lucas, G Chen, S Aras, J Wang Life science alliance 1 (2), 2018 | 64 | 2018 |
Targeted killing of a mammalian cell based upon its specialized metabolic state PB Alexander, J Wang, SL McKnight Proceedings of the National Academy of Sciences 108 (38), 15828-15833, 2011 | 59 | 2011 |
p73 cooperates with DNA damage agents to induce apoptosis in MCF7 cells in a p53-dependent manner J Zhu, S Nozell, J Wang, J Jiang, W Zhou, X Chen Oncogene 20 (30), 4050-4057, 2001 | 57 | 2001 |
Sustained hydrogen peroxide induces iron uptake by transferrin receptor-1 independent of the iron regulatory protein/iron-responsive element network B Andriopoulos, S Hegedüsch, J Mangin, HD Riedel, U Hebling, J Wang, ... Journal of Biological Chemistry 282 (28), 20301-20308, 2007 | 56 | 2007 |
The prolyl 4-hydroxylase inhibitor ethyl-3, 4-dihydroxybenzoate generates effective iron deficiency in cultured cells J Wang, JL Buss, G Chen, P Ponka, K Pantopoulos FEBS letters 529 (2-3), 309-312, 2002 | 55 | 2002 |
Metabolic Specialization of Mouse Embryonic Stem Cells J Wang, P Alexander, SL McKnight Cold Spring Harbor Symposia on Quantitative Biology, 2011 | 49 | 2011 |
Nitric oxide inhibits the degradation of IRP2 J Wang, G Chen, K Pantopoulos Molecular and cellular biology 25 (4), 1347-1353, 2005 | 44 | 2005 |
Loss of ABHD5 promotes the aggressiveness of prostate cancer cells G Chen, G Zhou, S Aras, Z He, S Lucas, I Podgorski, W Skar, ... Scientific reports 7 (1), 13021, 2017 | 42 | 2017 |
Sodium nitroprusside promotes IRP2 degradation via an increase in intracellular iron and in the absence of S nitrosylation at C178 J Wang, C Fillebeen, G Chen, B Andriopoulos, K Pantopoulos Molecular and cellular biology 26 (5), 1948-1954, 2006 | 40 | 2006 |