Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia T Schenk, WC Chen, S Göllner, L Howell, L Jin, K Hebestreit, HU Klein, ... Nature medicine 18 (4), 605-611, 2012 | 706 | 2012 |
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia S Göllner, T Oellerich, S Agrawal-Singh, T Schenk, HU Klein, C Rohde, ... Nature medicine 23 (1), 69-78, 2017 | 231 | 2017 |
Unlocking the potential of retinoic acid in anticancer therapy T Schenk, S Stengel, A Zelent British journal of cancer 111 (11), 2039-2045, 2014 | 172 | 2014 |
Retinoic acid and its derivatives in skin Ł Szymański, R Skopek, M Palusińska, T Schenk, S Stengel, S Lewicki, ... Cells 9 (12), 2660, 2020 | 115 | 2020 |
Hypomethylation of PRAME is responsible for its aberrant overexpression in human malignancies T Schenk, S Stengel, S Goellner, D Steinbach, HP Saluz Genes, Chromosomes and Cancer 46 (9), 796-804, 2007 | 85 | 2007 |
Interference with Sin3 function induces epigenetic reprogramming and differentiation in breast cancer cells EF Farias, K Petrie, B Leibovitch, J Murtagh, MB Chornet, T Schenk, ... Proceedings of the National Academy of Sciences 107 (26), 11811-11816, 2010 | 79 | 2010 |
Childhood acute myelogenous leukaemia: association between PRAME, apoptosis-and MDR-related gene expression S Goellner, D Steinbach, T Schenk, B Gruhn, F Zintl, E Ramsay, HP Saluz European Journal of Cancer 42 (16), 2807-2814, 2006 | 42 | 2006 |
The acetyltransferase GCN5 maintains ATRA-resistance in non-APL AML M Kahl, A Brioli, M Bens, F Perner, A Kresinsky, U Schnetzke, A Hinze, ... Leukemia 33 (11), 2628-2639, 2019 | 35 | 2019 |
High-intensity UV laser ChIP-seq for the study of protein-DNA interactions in living cells A Steube, T Schenk, A Tretyakov, HP Saluz Nature Communications 8 (1), 1303, 2017 | 30 | 2017 |
Choosing the right cell line for acute myeloid leukemia (AML) research R Skopek, M Palusińska, K Kaczor-Keller, R Pingwara, ... International journal of molecular sciences 24 (6), 5377, 2023 | 19 | 2023 |
Kami nski, P T Schenk, S Stengel, S Lewicki, L Kraj Zelent, A. Retinoic acid and its derivatives in skin. Cells 9, 2660, 2020 | 18 | 2020 |
Inhibition of the PI3K/AKT/mTOR pathway leads to down-regulation of c-Myc and overcomes resistance to ATRA in acute myeloid leukemia RT Swords, T Schenk, S Stengel, VS Gil, KR Petrie, A Perez, R Ana, ... Blood 126 (23), 1363, 2015 | 16 | 2015 |
Suppression of MYC by PI3K/AKT/mTOR pathway inhibition in combination with all-trans retinoic acid treatment for therapeutic gain in acute myeloid leukaemia S Stengel, KR Petrie, Y Sbirkov, C Stanko, FG Zadegan, V Gil, R Skopek, ... British journal of haematology, 2022 | 15 | 2022 |
Dual inhibition of EZH2 and G9A/GLP histone methyltransferases by HKMTI-1-005 promotes differentiation of acute myeloid leukemia cells Y Sbirkov, T Schenk, C Kwok, S Stengel, R Brown, G Brown, L Chesler, ... Frontiers in Cell and Developmental Biology 11, 1076458, 2023 | 12* | 2023 |
Tyrosine kinase inhibitor insensitivity of non‐cycling CD34+ human acute myeloid leukaemia cells with FMS‐like tyrosine kinase 3 mutations CL Alvares, T Schenk, S Hulkki, T Min, G Vijayaraghavan, J Yeung, ... British journal of haematology 154 (4), 457-465, 2011 | 9* | 2011 |
Investigating the interplay between myeloma cells and bone marrow stromal cells in the development of drug resistance: dissecting the role of epigenetic modifications J Schütt, T Nägler, T Schenk, A Brioli Cancers 13 (16), 4069, 2021 | 7 | 2021 |
The Protozoan Inhibitor Atovaquone Affects Mitochondrial Respiration and Shows In Vitro Efficacy Against Glucocorticoid-Resistant Cells in Childhood B-Cell Acute … Y Sbirkov, T Ivanova, H Burnusuzov, K Gercheva, K Petrie, T Schenk, ... Frontiers in oncology 11, 632181, 2021 | 4 | 2021 |
PAPAS promotes differentiation of mammary epithelial cells and suppresses breast carcinogenesis S Ren, F Bai, V Schnell, C Stanko, M Ritsch, T Schenk, E Barth, M Marz, ... Cell Reports 43 (1), 2024 | 2 | 2024 |
Targeting glutaminolysis shows efficacy in both prednisolone-sensitive and in metabolically rewired prednisolone-resistant B-cell childhood acute lymphoblastic leukaemia cells Y Sbirkov, B Vergov, V Dzharov, T Schenk, K Petrie, V Sarafian International journal of molecular sciences 24 (4), 3378, 2023 | 2 | 2023 |
Unraveling the complexity of drug resistance mechanisms to SINE, T cell-engaging therapies and CELMoDs in multiple myeloma: a comprehensive review J Schütt, K Brinkert, A Plis, T Schenk, A Brioli Cancer Drug Resistance 7, 2024 | | 2024 |