Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer’s disease and vascular cognitive impairment CE Van Skike, JB Jahrling, AB Olson, NL Sayre, SA Hussong, Z Ungvari, ... American Journal of Physiology-Heart and Circulatory Physiology, 2018 | 133 | 2018 |
Inborn errors of RNA lariat metabolism in humans with brainstem viral infection SY Zhang, NE Clark, CA Freije, E Pauwels, AJ Taggart, S Okada, ... Cell 172 (5), 952-965. e18, 2018 | 123 | 2018 |
Cerebral microvascular accumulation of tau oligomers in Alzheimer’s disease and related tauopathies DL Castillo-Carranza, AN Nilson, CE Van Skike, JB Jahrling, K Patel, ... Aging and disease 8 (3), 257, 2017 | 113 | 2017 |
Adult-onset CNS myelin sulfatide deficiency is sufficient to cause Alzheimer’s disease-like neuroinflammation and cognitive impairment S Qiu, JP Palavicini, J Wang, NS Gonzalez, S He, E Dustin, C Zou, L Ding, ... Molecular neurodegeneration 16, 1-24, 2021 | 80 | 2021 |
Effects of ethanol on hippocampal function during adolescence: a look at the past and thoughts on the future VS Chin, CE Van Skike, DB Matthews Alcohol 44 (1), 3-14, 2010 | 77 | 2010 |
mTOR drives cerebrovascular, synaptic, and cognitive dysfunction in normative aging CE Van Skike, AL Lin, R Roberts Burbank, JJ Halloran, SF Hernandez, ... Aging Cell 19 (1), e13057, 2020 | 72 | 2020 |
Acute alcohol and cognition: Remembering what it causes us to forget CE Van Skike, C Goodlett, DB Matthews Alcohol 79, 105-125, 2019 | 70 | 2019 |
Age‐related effects of alcohol from adolescent, adult, and aged populations using human and animal models LM Squeglia, J Boissoneault, CE Van Skike, SJ Nixon, DB Matthews Alcoholism: Clinical and Experimental Research 38 (10), 2509-2516, 2014 | 67 | 2014 |
Effect of acute ethanol and acute allopregnanolone on spatial memory in adolescent and adult rats VS Chin, CE Van Skike, RB Berry, RE Kirk, J Diaz-Granados, ... Alcohol 45 (5), 473-483, 2011 | 63 | 2011 |
Behavioral effects of ethanol in cerebellum are age dependent: potential system and molecular mechanisms CE Van Skike, P Botta, VS Chin, S Tokunaga, JM McDaniel, J Venard, ... Alcoholism: Clinical and Experimental Research 34 (12), 2070-2080, 2010 | 59 | 2010 |
Critical needs in drug discovery for cessation of alcohol and nicotine polysubstance abuse CE Van Skike, SE Maggio, AR Reynolds, EM Casey, MT Bardo, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 65, 269-287, 2016 | 51 | 2016 |
Chronic intermittent ethanol exposure produces persistent anxiety in adolescent and adult rats CE Van Skike, JL Diaz‐Granados, DB Matthews Alcoholism: clinical and experimental research 39 (2), 262-271, 2015 | 51 | 2015 |
Acute alcohol produces ataxia and cognitive impairments in aged animals: a comparison between young adult and aged rats A Novier, CE Van Skike, JL Diaz‐Granados, G Mittleman, DB Matthews Alcoholism: Clinical and Experimental Research 37 (8), 1317-1324, 2013 | 51 | 2013 |
mTOR drives cerebral blood flow and memory deficits in LDLR−/− mice modeling atherosclerosis and vascular cognitive impairment JB Jahrling, AL Lin, N DeRosa, SA Hussong, CE Van Skike, M Girotti, ... Journal of Cerebral Blood Flow & Metabolism 38 (1), 58-74, 2018 | 48 | 2018 |
A perfect sTORm: the role of the mammalian target of rapamycin (mTOR) in cerebrovascular dysfunction of Alzheimer's disease: a mini-review CE Van Skike, V Galvan Gerontology 64 (3), 205-211, 2018 | 47 | 2018 |
mTOR attenuation with rapamycin reverses neurovascular uncoupling and memory deficits in mice modeling Alzheimer's disease CE Van Skike, SA Hussong, SF Hernandez, AQ Banh, N DeRosa, ... Journal of Neuroscience 41 (19), 4305-4320, 2021 | 46 | 2021 |
The effects of acute alcohol on motor impairments in adolescent, adult, and aged rats LC Ornelas, A Novier, CE Van Skike, JL Diaz-Granados, DB Matthews Alcohol 49 (2), 121-126, 2015 | 39 | 2015 |
Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models ES Chocron, E Munkácsy, HS Kim, P Karpowicz, N Jiang, CE Van Skike, ... Science advances 8 (23), eabk2252, 2022 | 38 | 2022 |
Mammalian target of rapamycin at the crossroad between Alzheimer’s disease and diabetes H Liang, J Nie, CE Van Skike, JM Valentine, ME Orr Diabetes Mellitus: A risk factor for Alzheimer's Disease, 185-225, 2019 | 37 | 2019 |
Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy SA Hussong, AQ Banh, CE Van Skike, AO Dorigatti, SF Hernandez, ... Nature communications 14 (1), 2367, 2023 | 29 | 2023 |