| NF-κB–YY1–miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma H Wang, R Garzon, H Sun, KJ Ladner, R Singh, J Dahlman, A Cheng, ... Cancer cell 14 (5), 369-381, 2008 | 726 | 2008 |
| RNA splicing and disease: animal models to therapies M Montes, BL Sanford, DF Comiskey, DS Chandler Trends in Genetics 35 (1), 68-87, 2019 | 199 | 2019 |
| Apoptosis and expression of the bcl-2 proto-oncogene in the fetal and adult human kidney: evidence for the contribution of bcl-2 expression to renal carcinogenesis D Chandler, AK El-Naggar, S Brisbay, RW Redline, TJ McDonnell Human pathology 25 (8), 789-796, 1994 | 155 | 1994 |
| Genotoxic stress induces coordinately regulated alternative splicing of the p53 modulators MDM2 and MDM4 DS Chandler, RK Singh, LC Caldwell, JL Bitler, G Lozano Cancer research 66 (19), 9502-9508, 2006 | 129 | 2006 |
| miR-29 acts as a decoy in sarcomas to protect the tumor suppressor A20 mRNA from degradation by HuR MY Balkhi, OH Iwenofu, N Bakkar, KJ Ladner, DS Chandler, PJ Houghton, ... Science signaling 6 (286), ra63-ra63, 2013 | 98 | 2013 |
| Mouse models of SMA: tools for disease characterization and therapeutic development TW Bebee, CE Dominguez, DS Chandler Human genetics 131, 1277-1293, 2012 | 81 | 2012 |
| Modeling the human MTM1 p.R69C mutation in murine Mtm1 results in exon 4 skipping and a less severe myotubular myopathy phenotype CR Pierson, AN Dulin-Smith, AN Durban, ML Marshall, JT Marshall, ... Human molecular genetics 21 (4), 811-825, 2012 | 66 | 2012 |
| High frequency loss of heterozygosity in von Hippel-Lindau (VHL)-associated and sporadic pancreatic islet cell tumors: evidence for a stepwise mechanism for malignant … ST Lott, DS Chandler, SA Curley, CJ Foster, A El-Naggar, M Frazier, ... Cancer Research 62 (7), 1952-1955, 2002 | 55 | 2002 |
| Autoregulation of transformer-2 alternative splicing is necessary for normal male fertility in Drosophila ME McGuffin, D Chandler, D Somaiya, B Dauwalder, W Mattox Genetics 149 (3), 1477-1486, 1998 | 55 | 1998 |
| Splicing regulation of the survival motor neuron genes and implications for treatment of spinal muscular atrophy TW Bebee, JT Gladman, DS Chandler Frontiers in bioscience (Landmark edition) 15, 1191, 2010 | 52 | 2010 |
| Splicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage DF Comiskey Jr, AG Jacob, RK Singh, AS Tapia-Santos, DS Chandler Nucleic acids research 43 (8), 4202-4218, 2015 | 51 | 2015 |
| Evolutionary Conservation of Regulatory Strategies for the Sex Determination Factor transformer-2 D Chandler, ME McGuffin, J Piskur, J Yao, BS Baker, W Mattox Molecular and cellular biology 17 (5), 2908-2919, 1997 | 49 | 1997 |
| DEAR1 Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition N Chen, S Balasenthil, J Reuther, A Frayna, Y Wang, DS Chandler, ... Cancer discovery 3 (10), 1172-1189, 2013 | 48 | 2013 |
| DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence-free survival in early-onset breast cancer ST Lott, N Chen, DS Chandler, Q Yang, L Wang, M Rodriguez, H Xie, ... PLoS medicine 6 (5), e1000068, 2009 | 46 | 2009 |
| The splicing factor FUBP1 is required for the efficient splicing of oncogene MDM2 pre-mRNA AG Jacob, RK Singh, F Mohammad, TW Bebee, DS Chandler Journal of Biological Chemistry 289 (25), 17350-17364, 2014 | 45 | 2014 |
| Hypoxia is a modifier of SMN2 splicing and disease severity in a severe SMA mouse model TW Bebee, CE Dominguez, S Samadzadeh-Tarighat, KL Akehurst, ... Human molecular genetics 21 (19), 4301-4313, 2012 | 39 | 2012 |
| A humanized Smn gene containing the SMN2 nucleotide alteration in exon 7 mimics SMN2 splicing and the SMA disease phenotype JT Gladman, TW Bebee, C Edwards, X Wang, Z Sahenk, MM Rich, ... Human molecular genetics 19 (21), 4239-4252, 2010 | 39 | 2010 |
| Advances in pediatric rhabdomyosarcoma characterization and disease model development D O’Brien, AG Jacob, SJ Qualman, DS Chandler Histology and histopathology 27 (1), 13, 2012 | 38 | 2012 |
| MDM2 and MDM4 splicing: an integral part of the cancer spliceome S Jeyaraj, DM O’Brien, DS Chandler Front Biosci 14, 2647-2656, 2009 | 38 | 2009 |
| Direct repression of splicing by transformer-2 DS Chandler, J Qi, W Mattox Molecular and cellular biology, 2003 | 36 | 2003 |
