Challenges with advanced therapy medicinal products and how to meet them Nature reviews Drug discovery 9 (3), 195-201, 2010 | 207 | 2010 |
p53 interacts with p34cdc2 in mammalian cells: implications for cell cycle control and oncogenesis. HW Stürzbecher, T Maimets, P Chumakov, R Brain, C Addison, V Simanis, ... Oncogene 5 (6), 795-781, 1990 | 191 | 1990 |
Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells T Maimets, I Neganova, L Armstrong, M Lako Oncogene 27 (40), 5277-5287, 2008 | 156 | 2008 |
Characterization of a novel cytotoxic cell‐penetrating peptide derived from p14ARF protein HJ Johansson, S El-Andaloussi, T Holm, M Mäe, J Jänes, T Maimets, ... Molecular Therapy 16 (1), 115-123, 2008 | 125 | 2008 |
Mouse p53 blocks SV40 DNA replication in vitro and downregulates T antigen DNA helicase activity. HW Stürzbecher, R Brain, T Maimets, C Addison, K Rudge, JR Jenkins Oncogene 3 (4), 405-413, 1988 | 84 | 1988 |
ARF and ATM/ATR cooperate in p53-mediated apoptosis upon oncogenic stress S Pauklin, A Kristjuhan, T Maimets, V Jaks Biochemical and biophysical research communications 334 (2), 386-394, 2005 | 71 | 2005 |
p53 protein is a suppressor of papillomavirus DNA amplificational replication D Lepik, I Ilves, A Kristjuhan, T Maimets, M Ustav Journal of virology 72 (8), 6822-6831, 1998 | 66 | 1998 |
Pre-administration of PepFect6-microRNA-146a nanocomplexes inhibits inflammatory responses in keratinocytes and in a mouse model of irritant contact dermatitis E Urgard, A Lorents, M Klaas, K Padari, J Viil, T Runnel, K Langel, ... Journal of Controlled Release 235, 195-204, 2016 | 47 | 2016 |
p53-dependent transcription can exhibit both on/off and graded response after genotoxic stress A Joers, V Jaks, J Kase, T Maimets Oncogene 23 (37), 6175-6185, 2004 | 46 | 2004 |
SOX2 is regulated differently from NANOG and OCT4 in human embryonic stem cells during early differentiation initiated with sodium butyrate A Kallas, M Pook, A Trei, T Maimets Stem cells international 2014 (1), 298163, 2014 | 43 | 2014 |
Nocodazole treatment decreases expression of pluripotency markers Nanog and Oct4 in human embryonic stem cells A Kallas, M Pook, M Maimets, K Zimmermann, T Maimets PLoS One 6 (4), e19114, 2011 | 42 | 2011 |
Electroporation and carrier DNA cause p53 activation, cell cycle arrest, and apoptosis D Lepik, V Jaks, L Kadaja, S Värv, T Maimets Analytical biochemistry 318 (1), 52-59, 2003 | 38 | 2003 |
A human tumour-derived mutant p53 protein induces a p34cdc2 reversible growth arrest in fission yeast. P Wagner, V Simanis, T Maimets, E Keenan, C Addison, R Brain, ... Oncogene 6 (9), 1539-1547, 1991 | 33 | 1991 |
Overexpression of leukocyte marker CD43 causes activation of the tumor suppressor proteins p53 and ARF L Kadaja, S Laos, T Maimets Oncogene 23 (14), 2523-2530, 2004 | 32 | 2004 |
Tumour associated mutants of p53 can inhibit transcriptional activity of p53 without heterooligomerization A Joers, A Kristjuhan, L Kadaja, T Maimets Oncogene 17 (18), 2351-2358, 1998 | 28 | 1998 |
miR‐10a‐5p is increased in atopic dermatitis and has capacity to inhibit keratinocyte proliferation H Vaher, T Runnel, E Urgard, A Aab, G Carreras Badosa, J Maslovskaja, ... Allergy 74 (11), 2146-2156, 2019 | 27 | 2019 |
Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14 EH Ervin, M Pook, I Teino, V Kasuk, A Trei, M Pooga, T Maimets Stem Cell Research & Therapy 10, 1-14, 2019 | 26 | 2019 |
p53 protein accumulation in addition to the transactivation activity is required for p53-dependent cell cycle arrest after treatment of cells with camptothecin V Jaks, A Jõers, A Kristjuhan, T Maimets Oncogene 20 (10), 1212-1219, 2001 | 26 | 2001 |
Colon cancer cell differentiation by sodium butyrate modulates metabolic plasticity of Caco-2 cells via alteration of phosphotransfer network L Klepinina, A Klepinin, L Truu, V Chekulayev, H Vija, K Kuus, I Teino, ... PLoS One 16 (1), e0245348, 2021 | 25 | 2021 |
Interim evaluation of the seventh framework programme: report of the expert group R Annerberg, I Begg, H Acherson, S Borrás, A Hallen, T Maimets, ... European Commission, 2010 | 25 | 2010 |