Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: a multivariable Mendelian randomisation analysis TG Richardson, E Sanderson, TM Palmer, M Ala-Korpela, BA Ference, ... PLoS medicine 17 (3), e1003062, 2020 | 572 | 2020 |
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases J Zheng, V Haberland, D Baird, V Walker, PC Haycock, MR Hurle, ... Nature genetics 52 (10), 1122-1131, 2020 | 400 | 2020 |
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals A Giri, JN Hellwege, JM Keaton, J Park, C Qiu, HR Warren, ES Torstenson, ... Nature genetics 51 (1), 51-62, 2019 | 375 | 2019 |
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ... Nature genetics 53 (9), 1311-1321, 2021 | 245 | 2021 |
Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study TG Richardson, E Sanderson, B Elsworth, K Tilling, GD Smith Bmj 369, 2020 | 221 | 2020 |
An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome TG Richardson, S Harrison, G Hemani, G Davey Smith Elife 8, e43657, 2019 | 182 | 2019 |
Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight LK Küpers, C Monnereau, GC Sharp, P Yousefi, LA Salas, A Ghantous, ... Nature communications 10 (1), 1893, 2019 | 172 | 2019 |
Combined Effect of PNPLA3, TM6SF2, and HSD17B13 Variants on Risk of Cirrhosis and Hepatocellular Carcinoma in the General Population H Gellert‐Kristensen, TG Richardson, G Davey Smith, BG Nordestgaard, ... Hepatology 72 (3), 845-856, 2020 | 169 | 2020 |
Plasma proteomic associations with genetics and health in the UK Biobank BB Sun, J Chiou, M Traylor, C Benner, YH Hsu, TG Richardson, ... Nature 622 (7982), 329-338, 2023 | 149 | 2023 |
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals P Surendran, EV Feofanova, N Lahrouchi, I Ntalla, S Karthikeyan, J Cook, ... Nature genetics 52 (12), 1314-1332, 2020 | 132 | 2020 |
Genetic predictors of participation in optional components of UK Biobank J Tyrrell, J Zheng, R Beaumont, K Hinton, TG Richardson, AR Wood, ... Nature communications 12 (1), 886, 2021 | 122 | 2021 |
Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging DL McCartney, JL Min, RC Richmond, AT Lu, MK Sobczyk, G Davies, ... Genome biology 22, 1-25, 2021 | 117 | 2021 |
DNA methylation links prenatal smoking exposure to later life health outcomes in offspring P Wiklund, V Karhunen, RC Richmond, P Parmar, A Rodriguez, ... Clinical epigenetics 11, 1-16, 2019 | 111 | 2019 |
Associations of mitochondrial and nuclear mitochondrial variants and genes with seven metabolic traits AT Kraja, C Liu, JL Fetterman, M Graff, CT Have, C Gu, LR Yanek, ... The American Journal of Human Genetics 104 (1), 112-138, 2019 | 111 | 2019 |
Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug development MV Holmes, TG Richardson, BA Ference, NM Davies, G Davey Smith Nature Reviews Cardiology 18 (6), 435-453, 2021 | 109 | 2021 |
Hypertensive disorders of pregnancy and DNA methylation in newborns: findings from the pregnancy and childhood epigenetics consortium N Kazmi, GC Sharp, SE Reese, FO Vehmeijer, J Lahti, CM Page, ... Hypertension 74 (2), 375-383, 2019 | 94 | 2019 |
Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation TG Richardson, GM Leyden, Q Wang, JA Bell, B Elsworth, G Davey Smith, ... PLoS biology 20 (2), e3001547, 2022 | 90 | 2022 |
Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization JL Treur, D Demontis, GD Smith, H Sallis, TG Richardson, RW Wiers, ... Addiction biology 26 (1), e12849, 2021 | 79 | 2021 |
Genetic regulation of the human plasma proteome in 54,306 UK Biobank participants BB Sun, J Chiou, M Traylor, C Benner, YH Hsu, TG Richardson, ... BioRxiv, 2022.06. 17.496443, 2022 | 75 | 2022 |
Mendelian randomization analysis identifies CpG sites as putative mediators for genetic influences on cardiovascular disease risk TG Richardson, J Zheng, GD Smith, NJ Timpson, TR Gaunt, CL Relton, ... The American Journal of Human Genetics 101 (4), 590-602, 2017 | 75 | 2017 |