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Tom G Richardson
Tom G Richardson
在 gsk.com 的电子邮件经过验证
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Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: a multivariable Mendelian randomisation analysis
TG Richardson, E Sanderson, TM Palmer, M Ala-Korpela, BA Ference, ...
PLoS medicine 17 (3), e1003062, 2020
5722020
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
J Zheng, V Haberland, D Baird, V Walker, PC Haycock, MR Hurle, ...
Nature genetics 52 (10), 1122-1131, 2020
4002020
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
A Giri, JN Hellwege, JM Keaton, J Park, C Qiu, HR Warren, ES Torstenson, ...
Nature genetics 51 (1), 51-62, 2019
3752019
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ...
Nature genetics 53 (9), 1311-1321, 2021
2452021
Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study
TG Richardson, E Sanderson, B Elsworth, K Tilling, GD Smith
Bmj 369, 2020
2212020
An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome
TG Richardson, S Harrison, G Hemani, G Davey Smith
Elife 8, e43657, 2019
1822019
Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight
LK Küpers, C Monnereau, GC Sharp, P Yousefi, LA Salas, A Ghantous, ...
Nature communications 10 (1), 1893, 2019
1722019
Combined Effect of PNPLA3, TM6SF2, and HSD17B13 Variants on Risk of Cirrhosis and Hepatocellular Carcinoma in the General Population
H Gellert‐Kristensen, TG Richardson, G Davey Smith, BG Nordestgaard, ...
Hepatology 72 (3), 845-856, 2020
1692020
Plasma proteomic associations with genetics and health in the UK Biobank
BB Sun, J Chiou, M Traylor, C Benner, YH Hsu, TG Richardson, ...
Nature 622 (7982), 329-338, 2023
1492023
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
P Surendran, EV Feofanova, N Lahrouchi, I Ntalla, S Karthikeyan, J Cook, ...
Nature genetics 52 (12), 1314-1332, 2020
1322020
Genetic predictors of participation in optional components of UK Biobank
J Tyrrell, J Zheng, R Beaumont, K Hinton, TG Richardson, AR Wood, ...
Nature communications 12 (1), 886, 2021
1222021
Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging
DL McCartney, JL Min, RC Richmond, AT Lu, MK Sobczyk, G Davies, ...
Genome biology 22, 1-25, 2021
1172021
DNA methylation links prenatal smoking exposure to later life health outcomes in offspring
P Wiklund, V Karhunen, RC Richmond, P Parmar, A Rodriguez, ...
Clinical epigenetics 11, 1-16, 2019
1112019
Associations of mitochondrial and nuclear mitochondrial variants and genes with seven metabolic traits
AT Kraja, C Liu, JL Fetterman, M Graff, CT Have, C Gu, LR Yanek, ...
The American Journal of Human Genetics 104 (1), 112-138, 2019
1112019
Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug development
MV Holmes, TG Richardson, BA Ference, NM Davies, G Davey Smith
Nature Reviews Cardiology 18 (6), 435-453, 2021
1092021
Hypertensive disorders of pregnancy and DNA methylation in newborns: findings from the pregnancy and childhood epigenetics consortium
N Kazmi, GC Sharp, SE Reese, FO Vehmeijer, J Lahti, CM Page, ...
Hypertension 74 (2), 375-383, 2019
942019
Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation
TG Richardson, GM Leyden, Q Wang, JA Bell, B Elsworth, G Davey Smith, ...
PLoS biology 20 (2), e3001547, 2022
902022
Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization
JL Treur, D Demontis, GD Smith, H Sallis, TG Richardson, RW Wiers, ...
Addiction biology 26 (1), e12849, 2021
792021
Genetic regulation of the human plasma proteome in 54,306 UK Biobank participants
BB Sun, J Chiou, M Traylor, C Benner, YH Hsu, TG Richardson, ...
BioRxiv, 2022.06. 17.496443, 2022
752022
Mendelian randomization analysis identifies CpG sites as putative mediators for genetic influences on cardiovascular disease risk
TG Richardson, J Zheng, GD Smith, NJ Timpson, TR Gaunt, CL Relton, ...
The American Journal of Human Genetics 101 (4), 590-602, 2017
752017
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