Differential roles of Smad2 and Smad3 in the regulation of TGF-β1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1 H Ungefroren, S Groth, S Sebens, H Lehnert, F Gieseler, F Fändrich Molecular cancer 10, 1-16, 2011 | 141 | 2011 |
Anti-p200 pemphigoid S Goletz, T Hashimoto, D Zillikens, E Schmidt Journal of the American Academy of Dermatology 71 (1), 185-191, 2014 | 130 | 2014 |
Structural proteins of the dermal‐epidermal junction targeted by autoantibodies in pemphigoid diseases S Goletz, D Zillikens, E Schmidt Experimental dermatology 26 (12), 1154-1162, 2017 | 110 | 2017 |
IL-17A is functionally relevant and a potential therapeutic target in bullous pemphigoid L Chakievska, MM Holtsche, A Künstner, S Goletz, BS Petersen, D Thaci, ... Journal of autoimmunity 96, 104-112, 2019 | 102 | 2019 |
Regulatory T-cell deficiency leads to pathogenic bullous pemphigoid antigen 230 autoantibody and autoimmune bullous disease S Haeberle, X Wei, K Bieber, S Goletz, RJ Ludwig, E Schmidt, AH Enk, ... Journal of Allergy and Clinical Immunology 142 (6), 1831-1842. e7, 2018 | 94 | 2018 |
Autoimmune pre-disease K Bieber, JE Hundt, X Yu, M Ehlers, F Petersen, CM Karsten, J Köhl, ... Autoimmunity reviews 22 (2), 103236, 2023 | 80 | 2023 |
Fcγ receptors III and IV mediate tissue destruction in a novel adult mouse model of bullous pemphigoid FS Schulze, T Beckmann, F Nimmerjahn, A Ishiko, M Collin, J Köhl, ... The American journal of pathology 184 (8), 2185-2196, 2014 | 78 | 2014 |
A sensitive and specific assay for the serological diagnosis of antilaminin 332 mucous membrane pemphigoid S Goletz, C Probst, L Komorowski, W Schlumberger, K Fechner, ... British Journal of Dermatology 180 (1), 149-156, 2019 | 77 | 2019 |
Pathogenicity of autoantibodies in anti-p200 pemphigoid K Vafia, S Groth, T Beckmann, M Hirose, J Dworschak, A Recke, ... PLoS One 7 (7), e41769, 2012 | 66 | 2012 |
Experimental laminin 332 mucous membrane pemphigoid critically involves C5aR1 and reflects clinical and immunopathological characteristics of the human disease EN Heppe, S Tofern, FS Schulze, A Ishiko, A Shimizu, C Sina, D Zillikens, ... Journal of Investigative Dermatology 137 (8), 1709-1718, 2017 | 63 | 2017 |
Prospective studies on the routine use of a novel multivariant enzyme-linked immunosorbent assay for the diagnosis of autoimmune bullous diseases N van Beek, C Dähnrich, N Johannsen, S Lemcke, S Goletz, F Hübner, ... Journal of the American Academy of Dermatology 76 (5), 889-894. e5, 2017 | 62 | 2017 |
Enzymatic autoantibody glycan hydrolysis alleviates autoimmunity against type VII collagen M Hirose, K Vafia, K Kalies, S Groth, J Westermann, D Zillikens, ... Journal of autoimmunity 39 (4), 304-314, 2012 | 61 | 2012 |
Dissecting the role of TGF-beta type I receptor/ALK5 in pancreatic ductal adenocarcinoma: Smad activation is crucial for both the tumor suppressive and prometastatic function B Schniewind, S Groth, S Sebens Müerköster, B Sipos, H Schäfer, ... Oncogene 26 (33), 4850-4862, 2007 | 60 | 2007 |
Transforming growth factor-β (TGF-β) type I receptor/ALK5-dependent activation of the GADD45β gene mediates the induction of biglycan expression by TGF-β H Ungefroren, S Groth, M Ruhnke, H Kalthoff, F Fändrich Journal of Biological Chemistry 280 (4), 2644-2652, 2005 | 60 | 2005 |
Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling H Ungefroren, S Sebens, K Giehl, O Helm, S Groth, F Fändrich, C Röcken, ... Oncotarget 5 (1), 277, 2014 | 59 | 2014 |
Differential roles of Src in transforming growth factor-ß regulation of growth arrest, epithelial-to-mesenchymal transition and cell migration in pancreatic ductal … H Ungefroren, S Sebens, S Groth, F Gieseler, F Fändrich International journal of oncology 38 (3), 797-805, 2011 | 55 | 2011 |
The Src family kinase inhibitors PP2 and PP1 block TGF-beta1-mediated cellular responses by direct and differential inhibition of type I and type II TGF-beta receptors H Ungefroren, S Sebens, S Groth, F Gieseler, F Fandrich Current cancer drug targets 11 (4), 524-535, 2011 | 52 | 2011 |
Adhesion and Rac1-dependent regulation of biglycan gene expression by transforming growth factor-β: Evidence for oxidative signaling through NADPH oxidase S Groth, M Schulze, H Kalthoff, F Fändrich, H Ungefroren Journal of Biological Chemistry 280 (39), 33190-33199, 2005 | 51 | 2005 |
Aberrant expression and secretion of heat shock protein 90 in patients with bullous pemphigoid S Tukaj, K Kleszczyński, K Vafia, S Groth, D Meyersburg, P Trzonkowski, ... PLoS One 8 (7), e70496, 2013 | 50 | 2013 |
Prospective study in bullous pemphigoid: association of high serum anti‐BP180 IgG levels with increased mortality and reduced Karnofsky score MM Holtsche, S Goletz, N van Beek, D Zillikens, S Benoit, K Harman, ... British Journal of Dermatology 179 (4), 918-924, 2018 | 42 | 2018 |