| Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain OK Melemedjian, MN Asiedu, DV Tillu, R Sanoja, J Yan, A Lark, ... Mol Pain 7 (1), 70, 2011 | 229 | 2011 |
| IL-6-and NGF-induced rapid control of protein synthesis and nociceptive plasticity via convergent signaling to the eIF4F complex OK Melemedjian, MN Asiedu, DV Tillu, KA Peebles, J Yan, N Ertz, ... The Journal of Neuroscience 30 (45), 15113-15123, 2010 | 223 | 2010 |
| Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain DV Tillu, OK Melemedjian, MN Asiedu, N Qu, M De Felice, G Dussor, ... Mol Pain 8 (5), 8069-8, 2012 | 190 | 2012 |
| Spinal protein kinase M ζ underlies the maintenance mechanism of persistent nociceptive sensitization MN Asiedu, DV Tillu, OK Melemedjian, A Shy, R Sanoja, B Bodell, ... The Journal of Neuroscience 31 (18), 6646-6653, 2011 | 155 | 2011 |
| Acetazolamide and midazolam act synergistically to inhibit neuropathic pain M Asiedu, MH Ossipov, K Kaila, TJ Price Pain 148 (2), 302-308, 2010 | 128 | 2010 |
| Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity OK Melemedjian, DV Tillu, JK Moy, MN Asiedu, EK Mandell, S Ghosh, ... Mol Pain 10, 45, 2014 | 104 | 2014 |
| mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK OK Melemedjian, A Khoutorsky, RE Sorge, J Yan, MN Asiedu, A Valdez, ... PAIN® 154 (7), 1080-1091, 2013 | 104 | 2013 |
| BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state OK Melemedjian, DV Tillu, MN Asiedu, EK Mandell, JK Moy, VM Blute, ... Mol Pain 9 (12), 1-14, 2013 | 102 | 2013 |
| Spinal Dopaminergic Projections Control the Transition to Pathological Pain Plasticity via a D1/D5-Mediated Mechanism JYV Kim, DV Tillu, TL Quinn, GL Mejia, A Shy, MNK Asiedu, E Murad, ... The Journal of Neuroscience 35 (16), 6307-6317, 2015 | 85 | 2015 |
| Inhibition of Carbonic Anhydrase Augments GABA A Receptor-Mediated Analgesia via a Spinal Mechanism of Action MN Asiedu, GL Mejia, CA Hübner, K Kaila, TJ Price The Journal of Pain 15 (4), 395-406, 2014 | 45 | 2014 |
| Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice MN Asiedu, G Mejia, MK Ossipov, TP Malan, K Kaila, TJ Price The Journal of Pain 13 (6), 546-554, 2012 | 39 | 2012 |
| The protease-activated receptor-2-specific agonists 2-aminothiazol-4-yl-LIGRL-NH2 and 6-aminonicotinyl-LIGRL-NH2 stimulate multiple signaling pathways to induce physiological … AN Flynn, DV Tillu, MN Asiedu, J Hoffman, J Vagner, TJ Price, S Boitano Journal of Biological Chemistry 286 (21), 19076-19088, 2011 | 39 | 2011 |
| Development of highly potent protease-activated receptor 2 agonists via synthetic lipid tethering AN Flynn, J Hoffman, DV Tillu, CL Sherwood, Z Zhang, R Patek, ... The FASEB Journal 27 (4), 1498-1510, 2013 | 37 | 2013 |
| Meningeal norepinephrine produces headache behaviors in rats via actions both on dural afferents and fibroblasts X Wei, J Yan, D Tillu, M Asiedu, N Weinstein, O Melemedjian, T Price, ... Cephalalgia, 0333102414566861, 2015 | 28 | 2015 |
| Development and evaluation of small peptidomimetic ligands to protease-activated receptor-2 (PAR 2) through the use of lipid tethering S Boitano, J Hoffman, DV Tillu, MN Asiedu, Z Zhang, CL Sherwood, ... | 27 | 2014 |
| A weak PAR2 partial agonist that can block PAR2 signaling initiated via protease and/or potent peptidomimetics (794.5) S Boitano, A Flynn, J Hoffman, M Asiedu, Z Zhang, C Sherwood, K DeFea, ... The FASEB Journal 28 (1 Supplement), 794.5, 2014 | | 2014 |
| Spinal Sensitization Mechanisms Promoting Pain: Gabaergic Disinhibition and Pkmζ-Mediated Plasticity MN Asiedu The University of Arizona., 2012 | | 2012 |
| Dysregulation of protein translation in neuropathic pain is resolved by AMP Kinase activators O Melemedjian, D Tillu, M Asiedu, R Sanoja, J Johnson, K Peebles, J Yan, ... The Journal of Pain 12 (4), P32, 2011 | | 2011 |
| Subtype specific modulation of phasic and tonic GABAA receptors in spinal analgesia M Asiedu, G Mejia, K Kaila, T Price The Journal of Pain 12 (4), P42, 2011 | | 2011 |
| Novel and Specific Agonists to Protease-activated Receptor-2 (PAR-2) Stimulate Multiple Signaling Pathways to Induce a Physiological Response in vitro and in vivo A Flynn, DV Tillu, MNK Asiedu, J Hoffman, J Vagner, T Price, S Boitano The FASEB Journal 25 (1_MeetingAbstracts), 829.3, 2011 | | 2011 |
