Poly (ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia MJL Eliasson, K Sampei, AS Mandir, PD Hurn, RJ Traystman, J Bao, ... Nature medicine 3 (10), 1089-1095, 1997 | 1287 | 1997 |
Poly (ADP-ribose) polymerase, nitric oxide and cell death AA Pieper, A Verma, J Zhang, SH Snyder Trends in pharmacological sciences 20 (4), 171-181, 1999 | 663 | 1999 |
Discovery of a proneurogenic, neuroprotective chemical AA Pieper, S Xie, E Capota, SJ Estill, J Zhong, JM Long, GL Becker, ... Cell 142 (1), 39-51, 2010 | 429 | 2010 |
Poly (ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes AA Pieper, DJ Brat, DK Krug, CC Watkins, A Gupta, S Blackshaw, ... Proceedings of the National Academy of Sciences 96 (6), 3059-3064, 1999 | 415 | 1999 |
FGF21 mediates endocrine control of simple sugar intake and sweet taste preference by the liver S von Holstein-Rathlou, LD BonDurant, L Peltekian, MC Naber, TC Yin, ... Cell metabolism 23 (2), 335-343, 2016 | 357 | 2016 |
P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage G Wang, T Han, D Nijhawan, P Theodoropoulos, J Naidoo, S Yadavalli, ... Cell 158 (6), 1324-1334, 2014 | 258 | 2014 |
A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome CM Buchovecky, SD Turley, HM Brown, SM Kyle, JG McDonald, B Liu, ... Nature genetics 45 (9), 1013-1020, 2013 | 245 | 2013 |
The neuronal PAS domain protein 3 transcription factor controls FGF-mediated adult hippocampal neurogenesis in mice AA Pieper, X Wu, TW Han, SJ Estill, Q Dang, LC Wu, S Reece-Fincanon, ... Proceedings of the National Academy of Sciences 102 (39), 14052-14057, 2005 | 216 | 2005 |
Development of proneurogenic, neuroprotective small molecules KS MacMillan, J Naidoo, J Liang, L Melito, NS Williams, L Morlock, ... Journal of the American Chemical Society 133 (5), 1428-1437, 2011 | 211 | 2011 |
Myocardial postischemic injury is reduced by polyADPribose polymerase-1 gene disruption AA Pieper, T Walles, G Wei, EE Clements, A Verma, SH Snyder, ... Molecular medicine 6, 271-282, 2000 | 202 | 2000 |
Unesterified cholesterol accumulation in late endosomes/lysosomes causes neurodegeneration and is prevented by driving cholesterol export from this compartment A Aqul, B Liu, CM Ramirez, AA Pieper, SJ Estill, DK Burns, B Liu, JJ Repa, ... Journal of neuroscience 31 (25), 9404-9413, 2011 | 200 | 2011 |
Post-treatment with an inhibitor of poly (ADP-ribose) polymerase attenuates cerebral damage in focal ischemia K Takahashi, AA Pieper, SE Croul, J Zhang, SH Snyder, JH Greenberg Brain research 829 (1-2), 46-54, 1999 | 199 | 1999 |
Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis R Tesla, HP Wolf, P Xu, J Drawbridge, SJ Estill, P Huntington, ... Proceedings of the National Academy of Sciences 109 (42), 17016-17021, 2012 | 178 | 2012 |
The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis AK Walker, PD Rivera, Q Wang, JC Chuang, S Tran, ... Molecular psychiatry 20 (4), 500-508, 2015 | 171 | 2015 |
Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease H De Jesús-Cortés, P Xu, J Drawbridge, SJ Estill, P Huntington, S Tran, ... Proceedings of the National Academy of Sciences 109 (42), 17010-17015, 2012 | 171 | 2012 |
Poly (ADP‐ribose) synthetase activation: an early indicator of neurotoxic DNA damage J Zhang, A Pieper, SH Snyder Journal of neurochemistry 65 (3), 1411-1414, 1995 | 149 | 1995 |
Poly (ADP-ribosyl) ation basally activated by DNA strand breaks reflects glutamate–nitric oxide neurotransmission AA Pieper, S Blackshaw, EE Clements, DJ Brat, DK Krug, AJ White, ... Proceedings of the National Academy of Sciences 97 (4), 1845-1850, 2000 | 137 | 2000 |
Neurotoxicity in preclinical models of occupational exposure to organophosphorus compounds JR Voorhees, DS Rohlman, PJ Lein, AA Pieper Frontiers in neuroscience 10, 590, 2017 | 130 | 2017 |
Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment Y Zhou, J Xu, Y Hou, JB Leverenz, A Kallianpur, R Mehra, Y Liu, H Yu, ... Alzheimer's research & therapy 13 (1), 110, 2021 | 126 | 2021 |
P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury TC Yin, JK Britt, H De Jesús-Cortés, Y Lu, RM Genova, MZ Khan, ... Cell reports 8 (6), 1731-1740, 2014 | 125 | 2014 |