Histone deacetylase 1 can repress transcription by binding to Sp1 A Doetzlhofer, H Rotheneder, G Lagger, M Koranda, V Kurtev, G Brosch, ... Molecular and cellular biology 19 (8), 5504-5511, 1999 | 507 | 1999 |
Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells PM White, A Doetzlhofer, YS Lee, AK Groves, N Segil Nature 441 (7096), 984-987, 2006 | 485 | 2006 |
Math1-driven GFP expression in the developing nervous system of transgenic mice EA Lumpkin, T Collisson, P Parab, A Omer-Abdalla, H Haeberle, P Chen, ... Gene Expression Patterns 3 (4), 389-395, 2003 | 327 | 2003 |
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti A Doetzlhofer, ML Basch, T Ohyama, M Gessler, AK Groves, N Segil Developmental cell 16 (1), 58-69, 2009 | 273 | 2009 |
The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene G Lagger, A Doetzlhofer, B Schuettengruber, E Haidweger, E Simboeck, ... Molecular and cellular biology 23 (8), 2669-2679, 2003 | 257 | 2003 |
In vitro growth and differentiation of mammalian sensory hair cell progenitors: a requirement for EGF and periotic mesenchyme A Doetzlhofer, PM White, JE Johnson, N Segil, AK Groves Developmental biology 272 (2), 432-447, 2004 | 126 | 2004 |
p19Ink4d and p21Cip1 collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis H Laine, A Doetzlhofer, J Mantela, J Ylikoski, M Laiho, MF Roussel, ... Journal of Neuroscience 27 (6), 1434-1444, 2007 | 105 | 2007 |
Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochlea S Korrapati, I Roux, E Glowatzki, A Doetzlhofer PloS one 8 (8), e73276, 2013 | 94 | 2013 |
Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates ML Basch, RM Brown, HI Jen, F Semerci, F Depreux, RK Edlund, H Zhang, ... Elife 5, e19921, 2016 | 79 | 2016 |
Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling A Benito-Gonzalez, A Doetzlhofer Journal of Neuroscience 34 (38), 12865-12876, 2014 | 64 | 2014 |
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus PQ Duy, SC Weise, C Marini, XJ Li, D Liang, PJ Dahl, S Ma, A Spajic, ... Nature neuroscience 25 (4), 458-473, 2022 | 63 | 2022 |
LIN28B/ let-7 control the ability of neonatal murine auditory supporting cells to generate hair cells through mTOR signaling XJ Li, A Doetzlhofer Proc Natl Acad Sci U S A . 117 (36), 22225-22236, 2020 | 48 | 2020 |
The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea EJ Golden, A Benito-Gonzalez, A Doetzlhofer Proceedings of the National Academy of Sciences 112 (29), E3864-E3873, 2015 | 47 | 2015 |
Insights into inner ear-specific gene regulation: Epigenetics and non-coding RNAs in inner ear development and regeneration A Doetzlhofer, KB Avraham Seminars in cell & developmental biology 65, 69-79, 2017 | 41 | 2017 |
Prospective identification and purification of hair cell and supporting cell progenitors from the embryonic cochlea A Doetzlhofer, P White, YS Lee, A Groves, N Segil Brain research 1091 (1), 282-288, 2006 | 41 | 2006 |
Alternate Activation of Two Divergently Transcribed Mouse Genes from a Bidirectional Promoter Is Linked to Changes in Histone Modification B Schuettengruber, A Doetzlhofer, K Kroboth, E Wintersberger, C Seiser Journal of Biological Chemistry 278 (3), 1784-1793, 2003 | 34 | 2003 |
Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea XJ Li, C Morgan, LA Goff, A Doetzlhofer Science Advances 8 (6), eabj7651, 2022 | 30 | 2022 |
Canonical Notch signaling plays an instructive role in auditory supporting cell development DP Campbell, E Chrysostomou, A Doetzlhofer Scientific reports 6 (1), 19484, 2016 | 30 | 2016 |
Growth-regulated antisense transcription of the mouse thymidine kinase gene H Sutterluety, B Stefan, A Doetzlhofer, H Khier, E Wintersberger, C Seiser Nucleic acids research 26 (21), 4989-4995, 1998 | 23 | 1998 |
A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea M Prajapati-DiNubila, A Benito-Gonzalez, EJ Golden, S Zhang, ... Elife 8, e47613, 2019 | 22 | 2019 |