Precise gene editing preserves hematopoietic stem cell function following transient p53-mediated DNA damage response G Schiroli, A Conti, S Ferrari, L Della Volpe, A Jacob, L Albano, S Beretta, ... Cell stem cell 24 (4), 551-565. e8, 2019 | 268 | 2019 |
Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking S Ferrari, A Jacob, S Beretta, G Unali, L Albano, V Vavassori, D Cittaro, ... Nature biotechnology 38 (11), 1298-1308, 2020 | 132 | 2020 |
HIV-1-mediated insertional activation of STAT5B and BACH2 trigger viral reservoir in T regulatory cells D Cesana, FR Santoni de Sio, L Rudilosso, P Gallina, A Calabria, ... Nature communications 8 (1), 498, 2017 | 104 | 2017 |
Learning the structure of Bayesian Networks: A quantitative assessment of the effect of different algorithmic schemes S Beretta, M Castelli, I Gonçalves, R Henriques, D Ramazzotti Complexity 2018, 2018 | 63 | 2018 |
Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells S Ferrari, A Jacob, D Cesana, M Laugel, S Beretta, A Varesi, G Unali, ... Cell Stem Cell 29 (10), 1428-1444. e9, 2022 | 59 | 2022 |
Genotoxic effects of base and prime editing in human hematopoietic stem cells M Fiumara, S Ferrari, A Omer-Javed, S Beretta, L Albano, D Canarutto, ... Nature biotechnology, 1-15, 2023 | 46 | 2023 |
ASGAL: aligning RNA-Seq data to a splicing graph to detect novel alternative splicing events L Denti, R Rizzi, S Beretta, GD Vedova, M Previtali, P Bonizzoni BMC bioinformatics 19, 1-21, 2018 | 43 | 2018 |
Overlap graphs and de Bruijn graphs: data structures for de novo genome assembly in the big data era R Rizzi, S Beretta, M Patterson, Y Pirola, M Previtali, G Della Vedova, ... Quantitative Biology 7, 278-292, 2019 | 41 | 2019 |
Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper‐IgM syndrome V Vavassori, E Mercuri, GE Marcovecchio, MC Castiello, G Schiroli, ... EMBO Molecular Medicine 13 (3), e13545, 2021 | 40 | 2021 |
Targeted inducible delivery of immunoactivating cytokines reprograms glioblastoma microenvironment and inhibits growth in mouse models F Birocchi, M Cusimano, F Rossari, S Beretta, PMV Rancoita, A Ranghetti, ... Science translational medicine 14 (653), eabl4106, 2022 | 39 | 2022 |
Further steps in TANGO: improved taxonomic assignment in metagenomics D Alonso-Alemany, A Barré, S Beretta, P Bonizzoni, M Nikolski, ... Bioinformatics 30 (1), 17-23, 2014 | 35 | 2014 |
Integrated multiomic profiling identifies the epigenetic regulator PRC2 as a therapeutic target to counteract leukemia immune escape and relapse V Gambacorta, S Beretta, M Ciccimarra, L Zito, K Giannetti, A Andrisani, ... Cancer Discovery 12 (6), 1449-1461, 2022 | 30 | 2022 |
Hematopoietic stem cell function in β-thalassemia is impaired and is rescued by targeting the bone marrow niche A Aprile, A Gulino, M Storto, I Villa, S Beretta, I Merelli, A Rubinacci, ... Blood, The Journal of the American Society of Hematology 136 (5), 610-622, 2020 | 26 | 2020 |
VISPA2: a scalable pipeline for high-throughput identification and annotation of vector integration sites G Spinozzi, A Calabria, S Brasca, S Beretta, I Merelli, L Milanesi, ... BMC bioinformatics 18, 1-12, 2017 | 26 | 2017 |
Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis R Biavasco, E Lettera, K Giannetti, D Gilioli, S Beretta, A Conti, S Scala, ... Nature Communications 12 (1), 4559, 2021 | 23 | 2021 |
Modeling alternative splicing variants from RNA-Seq data with isoform graphs S Beretta, P Bonizzoni, GD Vedova, Y Pirola, R Rizzi Journal of Computational Biology 21 (1), 16-40, 2014 | 22 | 2014 |
Premature senescence and increased oxidative stress in the thymus of down syndrome patients GE Marcovecchio, F Ferrua, E Fontana, S Beretta, M Genua, I Bortolomai, ... Frontiers in Immunology 12, 669893, 2021 | 20 | 2021 |
In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases T Kerzel, G Giacca, S Beretta, C Bresesti, M Notaro, GM Scotti, ... Cancer Cell 41 (11), 1892-1910. e10, 2023 | 18 | 2023 |
A hybrid genetic algorithm for the repetition free longest common subsequence problem M Castelli, S Beretta, L Vanneschi Operations Research Letters 41 (6), 644-649, 2013 | 17 | 2013 |
HapCHAT: adaptive haplotype assembly for efficiently leveraging high coverage in long reads S Beretta, MD Patterson, S Zaccaria, G Della Vedova, P Bonizzoni Bmc Bioinformatics 19, 1-19, 2018 | 14 | 2018 |