Telomere shortening and tumor formation by mouse cells lacking telomerase RNA MA Blasco, HW Lee, MP Hande, E Samper, PM Lansdorp, RA DePinho, ... Cell 91 (1), 25-34, 1997 | 2680 | 1997 |
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts S Parrinello, E Samper, A Krtolica, J Goldstein, S Melov, J Campisi Nature cell biology 5 (8), 741-747, 2003 | 1338 | 2003 |
Conservation of the Notch signalling pathway in mammalian neurogenesis J Luis de la Pompa, A Wakeham, KM Correia, E Samper, S Brown, ... Development 124 (6), 1139-1148, 1997 | 805 | 1997 |
Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum JL de La Pompa, LA Timmerman, H Takimoto, H Yoshida, AJ Elia, ... Nature 392 (6672), 182-186, 1998 | 780 | 1998 |
Disease states associated with telomerase deficiency appear earlier in mice with short telomeres E Herrera, E Samper, J Martín‐Caballero, JM Flores, HW Lee, MA Blasco The EMBO journal, 1999 | 575 | 1999 |
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes E González‐Suárez, E Samper, A Ramírez, JM Flores, J Martín‐Caballero, ... The EMBO journal, 2001 | 446 | 2001 |
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis E González-Suárez, E Samper, JM Flores, MA Blasco Nature genetics 26 (1), 114-117, 2000 | 432 | 2000 |
Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice MP Hande, E Samper, P Lansdorp, MA Blasco The Journal of cell biology 144 (4), 589-601, 1999 | 426 | 1999 |
Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G‐strand overhang E Samper, FA Goytisolo, P Slijepcevic, PPW van Buul, MA Blasco EMBO reports, 2000 | 395 | 2000 |
Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc−/− mice with short telomeres E Samper, JM Flores, MA Blasco EMBO reports, 2001 | 334 | 2001 |
Culture of human mesenchymal stem cells at low oxygen tension improves growth and genetic stability by activating glycolysis JC Estrada, C Albo, A Benguria, A Dopazo, P Lopez-Romero, ... Cell Death & Differentiation 19 (5), 743-755, 2012 | 308 | 2012 |
Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals FA Goytisolo, E Samper, J Martín-Caballero, P Finnon, E Herrera, ... The Journal of experimental medicine 192 (11), 1625-1636, 2000 | 280 | 2000 |
Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy JC Estrada, Y Torres, A Benguria, A Dopazo, E Roche, ... Cell death & disease 4 (6), e691-e691, 2013 | 258 | 2013 |
The absence of the DNA-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G … FA Goytisolo, E Samper, S Edmonson, GE Taccioli, MA Blasco Molecular and cellular biology 21 (11), 3642-3651, 2001 | 243 | 2001 |
Telomere shortening in mTR−/− embryos is associated with failure to close the neural tube E Herrera, E Samper, MA Blasco The EMBO journal, 1999 | 185 | 1999 |
Telomere length abnormalities in mammalian radiosensitive cells J McIlrath, SD Bouffler, E Samper, A Cuthbert, A Wojcik, I Szumiel, ... Cancer research 61 (3), 912-915, 2001 | 178 | 2001 |
Long-term repopulating ability of telomerase-deficient murine hematopoietic stem cells E Samper, P Fernández, R Eguıa, L Martın-Rivera, A Bernad, MA Blasco, ... Blood, The Journal of the American Society of Hematology 99 (8), 2767-2775, 2002 | 170 | 2002 |
Mitochondrial oxidative stress causes chromosomal instability of mouse embryonic fibroblasts E Samper, DG Nicholls, S Melov Aging cell 2 (5), 277-285, 2003 | 146 | 2003 |
Breaks at telomeres and TRF2-independent end fusions in Fanconi anemia E Callén, E Samper, MJ Ramírez, A Creus, R Marcos, JJ Ortega, T Olivé, ... Human molecular genetics 11 (4), 439-444, 2002 | 122 | 2002 |
Normal telomere length and chromosomal end capping in poly (ADP-ribose) polymerase–deficient mice and primary cells despite increased chromosomal instability E Samper, FA Goytisolo, JM Murcia, E González-Suárez, JC Cigudosa, ... The Journal of Cell Biology 154 (1), 49-60, 2001 | 121 | 2001 |