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Lizbé Koekemoer
Lizbé Koekemoer
CMD
在 cmd.ox.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ...
Cell stem cell 29 (2), 217-231. e8, 2022
1852022
A pantetheinase-resistant pantothenamide with potent, on-target, and selective antiplasmodial activity
CJ Macuamule, ET Tjhin, CE Jana, L Barnard, L Koekemoer, M De Villiers, ...
Antimicrobial agents and chemotherapy 59 (6), 3666-3668, 2015
522015
COVID moonshot: open science discovery of SARS-CoV-2 main protease inhibitors by combining crowdsourcing, high-throughput experiments, computational simulations, and machine …
H Achdout, A Aimon, E Bar-David, GM Morris
BioRxiv, 2020
502020
Novel and improved crystal structures of H. influenzae, E. coli and P. aeruginosa penicillin-binding protein 3 (PBP3) and N. gonorrhoeae PBP2: toward a better understanding of …
D Bellini, L Koekemoer, H Newman, CG Dowson
Journal of molecular biology 431 (18), 3501-3519, 2019
462019
Variation in pantothenate kinase type determines the pantothenamide mode of action and impacts on coenzyme A salvage biosynthesis
M de Villiers, L Barnard, L Koekemoer, JL Snoep, E Strauss
The FEBS journal 281 (20), 4731-4753, 2014
462014
Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors
COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ...
BioRxiv, 2020.10. 29.339317, 2020
392020
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors
ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ...
Science 382 (6671), eabo7201, 2023
372023
The low-cost Shifter microscope stage transforms the speed and robustness of protein crystal harvesting
ND Wright, P Collins, L Koekemoer, T Krojer, R Talon, E Nelson, M Ye, ...
Acta Crystallographica Section D: Structural Biology 77 (1), 62-74, 2021
342021
Spiropyrimidinetrione DNA gyrase inhibitors with potent and selective antituberculosis activity
P Govender, R Muller, K Singh, V Reddy, CJ Eyermann, S Fienberg, ...
Journal of medicinal chemistry 65 (9), 6903-6925, 2022
212022
3‐Fluoroaspartate and Pyruvoyl‐Dependant Aspartate Decarboxylase: Exploiting the Unique Characteristics of Fluorine To Probe Reactivity and Binding
J de Villiers, L Koekemoer, E Strauss
Chemistry–A European Journal 16 (33), 10030-10041, 2010
182010
An in-solution snapshot of SARS-COV-2 main protease maturation process and inhibition
GD Noske, Y Song, RS Fernandes, R Chalk, H Elmassoudi, L Koekemoer, ...
Nature Communications 14 (1), 1545, 2023
102023
The coenzyme A level modulator hopantenate (HoPan) inhibits phosphopantotenoylcysteine synthetase activity
KJ Mostert, N Sharma, M Van Der Zwaag, R Staats, L Koekemoer, ...
ACS chemical biology 16 (11), 2401-2414, 2021
92021
Expanding the Repertoire of Low‐Molecular‐Weight Pentafluorosulfanyl‐Substituted Scaffolds
A Jose, D Guest, R LeGay, GJ Tizzard, SJ Coles, M Derveni, E Wright, ...
ChemMedChem 17 (7), e202100641, 2022
72022
Analysis of the diverse antigenic landscape of the malaria invasion protein RH5 identifies a potent vaccine-induced human public antibody clonotype
JR Barrett, D Pipini, ND Wright, AJR Cooper, G Gorini, D Quinkert, ...
bioRxiv, 2023.10. 04.560576, 2023
32023
Multifaceted Target Specificity Analysis as a Tool in Antimicrobial Drug Development: Type III Pantothenate Kinases as a Case Study
SE Brigg, L Koekemoer, LA Brand, E Strauss
ChemMedChem 18 (7), e202200630, 2023
22023
High-throughput crystallography for rapid fragment growth from crude arrays by low-cost robotics
H Grosjean, A Aimon, S Hassell-Hart, W Thompson, L Koekemoer, ...
12023
Studies towards the selective inhibition of β-alanine pathways in Mycobacterium tuberculosis
L Koekemoer
Stellenbosch: University of Stellenbosch, 2006
12006
Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype
JR Barrett, D Pipini, ND Wright, AJR Cooper, G Gorini, D Quinkert, ...
Cell, 2024
2024
High-throughput crystallographic fragment screening of Zika virus NS3 Helicase
AS Godoy, NCMR Mesquita, GD Noske, VO Gawriljuk, RM Lithgo, ...
bioRxiv, 2024
2024
Crystallization of Zika virus NS2B-NS3 protease
P Marples, D Fearon, L Koekemoer
2024
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