| Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs MP Lokugamage, D Vanover, J Beyersdorf, MZC Hatit, L Rotolo, ... Nature biomedical engineering 5 (9), 1059-1068, 2021 | 242 | 2021 |
| Species-dependent in vivo mRNA delivery and cellular responses to nanoparticles MZC Hatit, MP Lokugamage, CN Dobrowolski, K Paunovska, H Ni, ... Nature nanotechnology 17 (3), 310-318, 2022 | 78 | 2022 |
| Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo H Ni, MZC Hatit, K Zhao, D Loughrey, MP Lokugamage, HE Peck, AD Cid, ... Nature Communications 13 (1), 4766, 2022 | 72 | 2022 |
| Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery C Dobrowolski, K Paunovska, E Schrader Echeverri, D Loughrey, ... Nature Nanotechnology 17 (8), 871-879, 2022 | 53 | 2022 |
| Nanoparticles containing constrained phospholipids deliver mRNA to liver immune cells in vivo without targeting ligands Z Gan, MP Lokugamage, MZC Hatit, D Loughrey, K Paunovska, M Sato, ... Bioengineering & translational medicine 5 (3), e10161, 2020 | 49 | 2020 |
| Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver CD Sago, MP Lokugamage, D Loughrey, KE Lindsay, R Hincapie, ... Nature biomedical engineering 6 (2), 157-167, 2022 | 45 | 2022 |
| Therapeutic RNA delivery for COVID and other diseases C Dobrowolski, K Paunovska, MZC Hatit, MP Lokugamage, JE Dahlman Advanced healthcare materials 10 (15), 2002022, 2021 | 38 | 2021 |
| A flow platform for degradation-free CuAAC bioconjugation MZC Hatit, LF Reichenbach, JM Tobin, F Vilela, GA Burley, AJB Watson Nature Communications 9 (1), 4021, 2018 | 35 | 2018 |
| The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in Vivo A Radmand, MP Lokugamage, H Kim, C Dobrowolski, R Zenhausern, ... Nano letters 23 (3), 993-1002, 2023 | 30 | 2023 |
| Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery MZC Hatit, CN Dobrowolski, MP Lokugamage, D Loughrey, H Ni, C Zurla, ... Nature Chemistry 15 (4), 508-515, 2023 | 27 | 2023 |
| Strategy for conditional orthogonal sequential CuAAC reactions using a protected aromatic ynamine MZC Hatit, CP Seath, AJB Watson, GA Burley The Journal of Organic Chemistry 82 (10), 5461-5468, 2017 | 25 | 2017 |
| Chemoselective sequential click ligations directed by enhanced reactivity of an aromatic ynamine MZC Hatit, JC Sadler, LA McLean, BC Whitehurst, CP Seath, ... Organic letters 18 (7), 1694-1697, 2016 | 25 | 2016 |
| Substituting racemic ionizable lipids with stereopure ionizable lipids can increase mRNA delivery AJDS Sanchez, K Zhao, SG Huayamares, MZC Hatit, MP Lokugamage, ... Journal of Controlled Release 353, 270-277, 2023 | 24 | 2023 |
| Universal Barcoding Predicts In Vivo ApoE-Independent Lipid Nanoparticle Delivery AJ Da Silva Sanchez, C Dobrowolski, A Cristian, ES Echeverri, K Zhao, ... Nano Letters 22 (12), 4822-4830, 2022 | 24 | 2022 |
| The extent to which lipid nanoparticles require apolipoprotein E and low-density lipoprotein receptor for delivery changes with ionizable lipid structure K Paunovska, AJ Da Silva Sanchez, MP Lokugamage, D Loughrey, ... Nano letters 22 (24), 10025-10033, 2022 | 17 | 2022 |
| Modular, step-efficient palladium-catalyzed cross-coupling strategy to access C6-heteroaryl 2-aminopurine ribonucleosides HS Buchanan, SM Pauff, TD Kosmidis, A Taladriz-Sender, OI Rutherford, ... Organic letters 19 (14), 3759-3762, 2017 | 17 | 2017 |
| Chemoselective Organoclick–Click Sequence M Belkheira, D El Abed, JM Pons, C Bressy Synthesis 50 (21), 4254-4262, 2018 | 10 | 2018 |
| Cationic cholesterol-dependent LNP delivery to lung stem cells, the liver, and heart A Radmand, H Kim, J Beyersdorf, CN Dobrowolski, R Zenhausern, ... Proceedings of the National Academy of Sciences 121 (11), e2307801120, 2024 | 7 | 2024 |
| Substituting Poly (ethylene glycol) Lipids with Poly (2‐ethyl‐2‐oxazoline) Lipids Improves Lipid Nanoparticle Repeat Dosing AJDS Sanchez, D Loughrey, ES Echeverri, SG Huayamares, A Radmand, ... Advanced Healthcare Materials, 2304033, 2024 | 6 | 2024 |
| Aromatic ynamines: a new bio-orthogonal reactive group for step-efficient, sequential bioconjugation M Hatit | | 2018 |
