High sensitivity top–down proteomics captures single muscle cell heterogeneity in large proteoforms JA Melby, KA Brown, ZR Gregorich, DS Roberts, EA Chapman, LE Ehlers, ... Proceedings of the National Academy of Sciences 120 (19), e2222081120, 2023 | 34 | 2023 |
Defining the sarcomeric proteoform landscape in ischemic cardiomyopathy by top-down proteomics EA Chapman, TJ Aballo, JA Melby, T Zhou, SJ Price, KJ Rossler, I Lei, ... Journal of proteome research 22 (3), 931-941, 2023 | 21 | 2023 |
Top-down proteomics of myosin light chain isoforms define chamber-specific expression in the human heart EF Bayne, KJ Rossler, ZR Gregorich, TJ Aballo, DS Roberts, ... Journal of Molecular and Cellular Cardiology 181, 89-97, 2023 | 7 | 2023 |
Structure and dynamics of endogenous cardiac troponin complex in human heart tissue captured by native nanoproteomics EA Chapman, DS Roberts, TN Tiambeng, J Andrews, MD Wang, ... Nature Communications 14 (1), 8400, 2023 | 6 | 2023 |
Native Top-Down Mass Spectrometry for Characterizing Sarcomeric Proteins Directly from Cardiac Tissue Lysate EA Chapman, BH Li, B Krichel, HJ Chan, KM Buck, DS Roberts, Y Ge Journal of the American Society for Mass Spectrometry 35 (4), 738-745, 2024 | 3 | 2024 |
Online mixed-bed ion exchange chromatography for native top-down proteomics of complex mixtures MS Fischer, HT Rogers, EA Chapman, HJ Chan, B Krichel, Z Gao, ... Journal of Proteome Research 23 (7), 2315-2322, 2024 | 2 | 2024 |
Integrated Proteomics Identifies Troponin I Isoform Switch as a Regulator of a Sarcomere-Metabolism Axis During Cardiac Regeneration TJ Aballo, J Bae, WG Paltzer, EA Chapman, RJ Salamon, MM Mann, Y Ge, ... bioRxiv, 2023 | 2 | 2023 |
Structure and dynamics of endogenous protein complexes in human heart tissue captured by native nanoproteomics EA Chapman, DS Roberts, TN Tiambeng, J Andrews, MD Wang, ... Research Square, 2023 | 1 | 2023 |
In-depth Characterization of S-Glutathionylation in Ventricular Myosin Light Chain 1 Across Species by Top-Down Proteomics EA Chapman, HT Rogers, Z Gao, HJ Chan, F Alvarado, Y Ge bioRxiv, 2024.12. 11.628048, 2024 | | 2024 |