Delivery of self-amplifying mRNA vaccines by cationic lipid nanoparticles: The impact of cationic lipid selection G Lou, G Anderluzzi, ST Schmidt, S Woods, S Gallorini, M Brazzoli, ... Journal of controlled release 325, 370-379, 2020 | 128 | 2020 |
Immunogenetics of Toxoplasma gondii informs vaccine design FL Henriquez, S Woods, H Cong, R McLeod, CW Roberts Trends in parasitology 26 (11), 550-555, 2010 | 57 | 2010 |
A novel microfluidic-based approach to formulate size-tuneable large unilamellar cationic liposomes: Formulation, cellular uptake and biodistribution investigations G Lou, G Anderluzzi, S Woods, CW Roberts, Y Perrie European Journal of Pharmaceutics and Biopharmaceutics 143, 51-60, 2019 | 56 | 2019 |
Salicylanilide inhibitors of Toxoplasma gondii A Fomovska, RD Wood, E Mui, JP Dubey, LR Ferreira, MR Hickman, ... Journal of medicinal chemistry 55 (19), 8375-8391, 2012 | 55 | 2012 |
New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections M McPhillie, Y Zhou, K El Bissati, J Dubey, H Lorenzi, M Capper, ... Scientific reports 6 (1), 29179, 2016 | 54 | 2016 |
Parasites lacking the micronemal protein MIC2 are deficient in surface attachment and host cell egress, but remain virulent in vivo S Gras, A Jackson, S Woods, G Pall, J Whitelaw, JM Leung, GE Ward, ... Wellcome open research 2, 2017 | 51 | 2017 |
Adjuvanted multi-epitope vaccines protect HLA-A* 11: 01 transgenic mice against Toxoplasma gondii K El Bissati, AA Chentoufi, PA Krishack, Y Zhou, S Woods, JP Dubey, ... JCI insight 1 (15), 2016 | 48 | 2016 |
The role of nanoparticle format and route of administration on self-amplifying mRNA vaccine potency G Anderluzzi, G Lou, S Woods, ST Schmidt, S Gallorini, M Brazzoli, ... Journal of Controlled Release 342, 388-399, 2022 | 46 | 2022 |
Toxoplasma gondii HLA-B* 0702-restricted GRA720-28 peptide with adjuvants and a universal helper T cell epitope elicits CD8+ T cells producing interferon-γ and reduces parasite … H Cong, EJ Mui, WH Witola, J Sidney, J Alexander, A Sette, A Maewal, ... Human immunology 73 (1), 1-10, 2012 | 46 | 2012 |
Design of a novel vaccine nanotechnology-based delivery system comprising CpGODN-protein conjugate anchored to liposomes D Chatzikleanthous, ST Schmidt, G Buffi, I Paciello, R Cunliffe, F Carboni, ... Journal of controlled release 323, 125-137, 2020 | 39 | 2020 |
MAP Kinase Phosphatase-2 Plays a Key Role in the Control of Infection with Toxoplasma gondii by Modulating iNOS and Arginase-1 Activities in Mice S Woods, J Schroeder, HA McGachy, R Plevin, CW Roberts, J Alexander PLoS pathogens 9 (8), e1003535, 2013 | 37 | 2013 |
Multi-Omics Studies Demonstrate Toxoplasma gondii-Induced Metabolic Reprogramming of Murine Dendritic Cells KE Hargrave, S Woods, O Millington, S Chalmers, GD Westrop, ... Frontiers in cellular and infection microbiology 9, 309, 2019 | 36 | 2019 |
Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase G Cheng, SP Muench, Y Zhou, GA Afanador, EJ Mui, A Fomovska, BS Lai, ... Bioorganic & medicinal chemistry letters 23 (7), 2035-2043, 2013 | 30 | 2013 |
Potent tetrahydroquinolone eliminates apicomplexan parasites MJ McPhillie, Y Zhou, MR Hickman, JA Gordon, CR Weber, Q Li, PJ Lee, ... Frontiers in cellular and infection microbiology 10, 203, 2020 | 28 | 2020 |
Exploitation of the bilosome platform technology to formulate antibiotics and enhance efficacy of melioidosis treatments RV D'Elia, S Woods, W Butcher, J McGahon, S Khadke, Y Perrie, ... Journal of controlled release 298, 202-212, 2019 | 28 | 2019 |
Modification of Triclosan Scaffold in Search of Improved Inhibitors for Enoyl‐Acyl Carrier Protein (ACP) Reductase in Toxoplasma gondii J Stec, A Fomovska, GA Afanador, SP Muench, Y Zhou, BS Lai, ... ChemMedChem 8 (7), 1138-1160, 2013 | 27 | 2013 |
Acanthamoeba activates macrophages predominantly through Toll-like receptor 4-and MyD88-dependent mechanisms to induce interleukin-12 (IL-12) and IL-6 A Cano, A Mattana, S Woods, FL Henriquez, J Alexander, CW Roberts Infection and immunity 85 (6), 10.1128/iai. 01054-16, 2017 | 22 | 2017 |
Rational design of adjuvants for subunit vaccines: The format of cationic adjuvants affects the induction of antigen-specific antibody responses G Anderluzzi, ST Schmidt, R Cunliffe, S Woods, CW Roberts, D Veggi, ... Journal of controlled release 330, 933-944, 2021 | 16 | 2021 |
Glucosamine-NISV delivers antibody across the blood-brain barrier: Optimization for treatment of encephalitic viruses S Woods, LM O'Brien, W Butcher, JE Preston, AR Georgian, ... Journal of controlled release 324, 644-656, 2020 | 13 | 2020 |
T Cell Hypo-Responsiveness against Leishmania major in MAP Kinase Phosphatase (MKP) 2 Deficient C57BL/6 Mice Does Not Alter the Healer Disease Phenotype J Schroeder, HA McGachy, S Woods, R Plevin, J Alexander PLoS neglected tropical diseases 7 (2), e2064, 2013 | 13 | 2013 |