Nanometric three-dimensional tracking of individual quantum dots in cells L Holtzer, T Meckel, T Schmidt Applied Physics Letters 90 (5), 2007 | 314 | 2007 |
Accurate determination of elastic parameters for multicomponent membranes S Semrau, T Idema, L Holtzer, T Schmidt, C Storm Physical review letters 100 (8), 088101, 2008 | 146 | 2008 |
Polarized endosome dynamics by spindle asymmetry during asymmetric cell division E Derivery, C Seum, A Daeden, S Loubéry, L Holtzer, F Jülicher, ... Nature 528 (7581), 280-285, 2015 | 129 | 2015 |
Nucleic acid templated chemical reaction in a live vertebrate L Holtzer, I Oleinich, M Anzola, E Lindberg, KK Sadhu, ... ACS central science 2 (6), 394-400, 2016 | 77 | 2016 |
Anthrax toxin receptor 2a controls mitotic spindle positioning I Castanon, L Abrami, L Holtzer, CP Heisenberg, FG Van Der Goot, ... Nature cell biology 15 (1), 28-39, 2013 | 56 | 2013 |
Enabling precision medicine by unravelling disease pathophysiology: quantifying signal transduction pathway activity across cell and tissue types A Van De Stolpe, L Holtzer, H van Ooijen, MA Inda, W Verhaegh Scientific reports 9 (1), 1603, 2019 | 54 | 2019 |
Quantification of biological interactions with particle image cross-correlation spectroscopy (PICCS) S Semrau, L Holtzer, M González-Gaitán, T Schmidt Biophysical journal 100 (7), 1810-1818, 2011 | 43 | 2011 |
BMP signaling gradient scaling in the zebrafish pectoral fin R Mateus, L Holtzer, C Seum, Z Hadjivasiliou, M Dubois, F Jülicher, ... Cell reports 30 (12), 4292-4302. e7, 2020 | 35 | 2020 |
Atomic force microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in a cooperative fashion F Moreno-Herrero, L Holtzer, DA Koster, S Shuman, C Dekker, NH Dekker Nucleic acids research 33 (18), 5945-5953, 2005 | 31 | 2005 |
Measurement of cellular immune response to viral infection and vaccination W Bouwman, W Verhaegh, L Holtzer, A Van de Stolpe Frontiers in immunology 11, 575074, 2020 | 25 | 2020 |
A molecular test for quantifying functional Notch signaling pathway activity in human cancer K Canté-Barrett, L Holtzer, H van Ooijen, R Hagelaar, V Cordo’, ... Cancers 12 (11), 3142, 2020 | 16 | 2020 |
Sara phosphorylation state controls the dispatch of endosomes from the central spindle during asymmetric division S Loubéry, A Daeden, C Seum, L Holtzer, A Moraleda, N Damond, ... Nature communications 8 (1), 15285, 2017 | 14 | 2017 |
The tracking of individual molecules in cells and tissues L Holtzer, T Schmidt Single Particle Tracking and Single Molecule Energy Transfer, 25-42, 2010 | 13 | 2010 |
Quantitative imaging of morphogen gradients in Drosophila imaginal discs A Kicheva, L Holtzer, O Wartlick, T Schmidt, M González-Gaitán Cold Spring Harbor Protocols 2013 (5), pdb. top074237, 2013 | 5 | 2013 |
Quantitative measurement of activity of JAK-STAT signaling pathways in blood samples and immune cells to predict innate and adaptive cellular immune response to viral infection … W Bouwman, W Verhaegh, L Holtzer, A van de Stolpe bioRxiv, 2020.05. 13.092759, 2020 | 4 | 2020 |
Measurement of activity of developmental signal transduction pathways to quantify stem cell pluripotency and phenotypically characterize differentiated cells Y Wesseling-Rozendaal, L Holtzer, W Verhaegh, A van de Stolpe bioRxiv, 2021.04. 14.439771, 2021 | 2 | 2021 |
Development of a Notch pathway assay and quantification of functional Notch pathway activity in T-cell acute lymphoblastic leukemia K Canté-Barrett, L Holtzer, H van Ooijen, R Hagelaar, V Cordo, ... bioRxiv, 2020.07. 10.183731, 2020 | 2 | 2020 |
Abstract A131: fulvestrant resistance in an MCF-7 model for breast cancer is associated with complete loss of ER pathway activity and gain of MAPK-AP1 pathway activity Y Wesseling-Rozendaal, A Stolpe, L Holtzer, MA Inda, P Wiel Molecular Cancer Therapeutics 18 (12_Supplement), A131-A131, 2019 | 2 | 2019 |
Signal transduction pathway activity during neoadjuvant treatment in esophageal adenocarcinomas A Creemers, SL Meijer, M Stoffels, GKJ Hooijer, L Holtzer, H van Ooijen, ... Annals of Oncology 29, viii211, 2018 | 2 | 2018 |
Morphogen Gradient Formation Unraveled Using In Vivo Three-dimensional Single Molecule Microscopy L Holtzer, A Kicheva, M Gonzalez-Gaitan, T Schmidt Biophysical Journal 96 (3), 33a, 2009 | 2 | 2009 |