Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR JJ Liu, R Horst, V Katritch, RC Stevens, K Wüthrich Science 335 (6072), 1106-1110, 2012 | 767 | 2012 |
NMR structure reveals intramolecular regulation mechanism for pheromone binding and release R Horst, F Damberger, P Luginbühl, P Güntert, G Peng, L Nikonova, ... Proceedings of the National Academy of Sciences 98 (25), 14374-14379, 2001 | 335 | 2001 |
Allosteric coupling of drug binding and intracellular signaling in the A2A adenosine receptor MT Eddy, MY Lee, ZG Gao, KL White, T Didenko, R Horst, M Audet, ... Cell 172 (1), 68-80. e12, 2018 | 206 | 2018 |
NMR characterization of a pH-dependent equilibrium between two folded solution conformations of the pheromone-binding protein from Bombyx mori F Damberger, L Nikonova, R Horst, G Peng, WS LEAL, K WÜTHRICH Protein Science 9 (5), 1038-1041, 2000 | 151 | 2000 |
Direct NMR observation of a substrate protein bound to the chaperonin GroEL R Horst, EB Bertelsen, J Fiaux, G Wider, AL Horwich, K Wüthrich Proceedings of the National Academy of Sciences 102 (36), 12748-12753, 2005 | 144 | 2005 |
Structural basis of chaperone–subunit complex recognition by the type 1 pilus assembly platform FimD M Nishiyama, R Horst, O Eidam, T Herrmann, O Ignatov, M Vetsch, ... The EMBO journal 24 (12), 2075-2086, 2005 | 140 | 2005 |
NMR structure of the unliganded Bombyx mori pheromone-binding protein at physiological pH D Lee, FF Damberger, G Peng, R Horst, P Güntert, L Nikonova, WS Leal, ... FEBS letters 531 (2), 314-318, 2002 | 127 | 2002 |
Fluorine-19 NMR of integral membrane proteins illustrated with studies of GPCRs T Didenko, JJ Liu, R Horst, RC Stevens, K Wüthrich Current opinion in structural biology 23 (5), 740-747, 2013 | 104 | 2013 |
Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus P Serrano, MA Johnson, MS Almeida, R Horst, T Herrmann, JS Joseph, ... Journal of virology 81 (21), 12049-12060, 2007 | 96 | 2007 |
β2-adrenergic receptor activation by agonists studied with 19F-NMR R Horst, JJ Liu, RC Stevens, K Wüthrich Angewandte Chemie (International ed. in English) 52 (41), 10762, 2013 | 94 | 2013 |
Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes J Schiemer, R Horst, Y Meng, JI Montgomery, Y Xu, X Feng, K Borzilleri, ... Nature Chemical Biology 17 (2), 152-160, 2021 | 70 | 2021 |
Microscale NMR screening of new detergents for membrane protein structural biology Q Zhang, R Horst, M Geralt, X Ma, WX Hong, MG Finn, RC Stevens Journal of the American Chemical Society 130 (23), 7357-7363, 2008 | 61 | 2008 |
The catalytic mechanism of cyclic GMP‐AMP synthase (cGAS) and implications for innate immunity and inhibition J Hall, EC Ralph, S Shanker, H Wang, LJ Byrnes, R Horst, J Wong, ... Protein Science 26 (12), 2367-2380, 2017 | 60 | 2017 |
Folding trajectories of human dihydrofolate reductase inside the GroEL–GroES chaperonin cavity and free in solution R Horst, WA Fenton, SW Englander, K Wüthrich, AL Horwich Proceedings of the National Academy of Sciences 104 (52), 20788-20792, 2007 | 59 | 2007 |
Solution‐NMR Characterization of Outer‐Membrane Protein A from E. coli in Lipid Bilayer Nanodiscs and Detergent Micelles L Sušac, R Horst, K Wüthrich Chembiochem 15 (7), 995-1000, 2014 | 52 | 2014 |
Managing the solvent water polarization to obtain improved NMR spectra of large molecular structures S Hiller, G Wider, T Etezady-Esfarjani, R Horst, K Wüthrich Journal of biomolecular NMR 32, 61-70, 2005 | 52 | 2005 |
Proton–proton Overhauser NMR spectroscopy with polypeptide chains in large structures R Horst, G Wider, J Fiaux, EB Bertelsen, AL Horwich, K Wüthrich Proceedings of the National Academy of Sciences 103 (42), 15445-15450, 2006 | 42 | 2006 |
NMR polypeptide backbone conformation of the E. coli outer membrane protein W R Horst, P Stanczak, K Wüthrich Structure 22 (8), 1204-1209, 2014 | 33 | 2014 |
Translational diffusion of macromolecular assemblies measured using transverse-relaxation-optimized pulsed field gradient NMR R Horst, AL Horwich, K Wüthrich Journal of the American Chemical Society 133 (41), 16354-16357, 2011 | 33 | 2011 |
NMR Characterization of Membrane Protein− Detergent Micelle Solutions by Use of Microcoil Equipment P Stanczak, R Horst, P Serrano, K Wüthrich Journal of the American Chemical Society 131 (51), 18450-18456, 2009 | 33 | 2009 |